PIPA5103741

CHD8 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5103741-Each-of-1 In Stock ₹ 43,592.82

PIPA5103741 - Each of 1

₹ 43,592.82

In Stock

Quantity

1

Base Price: ₹ 43,592.82

GST (18%): ₹ 7,846.708

Total Price: ₹ 51,439.528

Antigen

CHD8

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Chd8

Gene Alias

5830451P18Rik; ATP-dependent helicase CHD8; AU015341; AUTS18; Axis duplication inhibitor; beta-catenin binding protein; CHD8; CHD-8; chromodomain helicase DNA binding protein 8; chromodomain-helicase-DNA-binding protein 8; Duplin; helicase with SNF2 domain 1; HELSNF1; Kiaa1564; mKIAA1564

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

57680, 65027, 67772

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q09XV5, Q9HCK8, Q9JIX5

Gene Symbols

Chd8

Immunogen

A synthesized peptide derived from human CHD8(Accession Q9HCK8), corresponding to amino acid residues R2334-V2384.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total CHD8
  • DNA helicase that acts as a chromatin remodeling factor and regulates transcription
  • Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes
  • Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity
  • Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity
  • Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive genes
  • Involved in both enhancer blocking and epigenetic remodeling at chromatin boundary via its interaction with CTCF
  • Acts as a suppressor of STAT3 activity by suppressing the LIF-induced STAT3 transcriptional activity
  • Also acts as a transcription activator via its interaction with ZNF143 by participating in efficient U6 RNA polymerase III transcription.

Compare Similar Items

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Img

Thermo Scientific

PIPA5103741

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Antigen:
CHD8

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Chd8

Gene Alias:
5830451P18Rik; ATP-dependent helicase CHD8; AU015341; AUTS18; Axis duplication inhibitor; beta-catenin binding protein; CHD8; CHD-8; chromodomain helicase DNA binding protein 8; chromodomain-helicase-DNA-binding protein 8; Duplin; helicase with SNF2 domain 1; HELSNF1; Kiaa1564; mKIAA1564

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57680, 65027, 67772

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q09XV5, Q9HCK8, Q9JIX5

Gene Symbols:
Chd8

Immunogen:
A synthesized peptide derived from human CHD8(Accession Q9HCK8), corresponding to amino acid residues R2334-V2384.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5103742

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Antigen:
CHD9

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Chd9

Gene Alias:
1810014J18Rik; 9030205D12Rik; A330063D19Rik; AD013; AD-013; ATP-dependent helicase CHD9; BC022889; Chd9; CHD-9; chromatin remodeling factor CHROM1; chromatin-related mesenchymal modulator; Chromatin-remodeling factor CHROM1; chromodomain helicase DNA binding protein 9; chromodomain-helicase-DNA-binding protein 9; ciprofibrate bound protein p240; ciprofibrate-bound protein PRIC320; CReMM; FLJ12178; Kiaa0308; KISH2; Kismet homolog 2; mKIAA0308; peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein; PPAR{gamma}-interacting cofactor 320 kDa; PPAR-alpha-interacting complex protein 320 kDa; PRIC320; proteinx0008; x0008

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
109151, 80205

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q3L8U1, Q8BYH8

Gene Symbols:
Chd9

Immunogen:
A synthesized peptide derived from human CHD9(Accession Q3L8U1), corresponding to amino acid residues I1450-K1500.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5103743

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Antigen:
KIF4B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KIF4B

Gene Alias:
chromokinesin-B; Chromosome-associated kinesin KIF4B; KIF4B; kinesin family member 4B

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
285643

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q2VIQ3

Gene Symbols:
KIF4B

Immunogen:
A synthesized peptide derived from human KIF4B(Accession Q2VIQ3), corresponding to amino acid residues I1041-K1091.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5103746

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Antigen:
Claudin 20

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CLDN20

Gene Alias:
claudin 20; claudin-20; CLDN20; EG621628; testis secretory sperm-binding protein Li 229n

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
49861, 680178

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P56880

Gene Symbols:
CLDN20

Immunogen:
A synthesized peptide derived from human CLDN20(Accession P56880), corresponding to amino acid residues I166-K216.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG