PIPA5103788

POLE2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5103788-Each-of-1 In Stock ₹ 44,705.10

PIPA5103788 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

POLE2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

POLE2

Gene Alias

DNA pol epsilon2; DNA pol epsilonB; DNA polymerase epsilon 2, accessory subunit; DNA polymerase epsilon small subunit; DNA polymerase epsilon subunit 2; DNA polymerase epsilon subunit B; DNA polymerase epsilon, subunit 2; DNA polymerase II subunit 2; DNApol epsilon2; DNApol epsilonB; DPE2; POLE2; polymerase (DNA directed), epsilon 2 (p59 subunit); polymerase (DNA directed), epsilon 2, accessory subunit; polymerase (DNA) epsilon 2, accessory subunit

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

18974, 5427

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O54956, P56282

Gene Symbols

POLE2

Immunogen

A synthesized peptide derived from human POLE2(Accession P56282), corresponding to amino acid residues L477-F527.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Description

  • Antibody detects endogenous levels of total POLE2
  • DNA replication, recombination and repair, all of which are necessary for genome stability, require the presence of exonucleases
  • In DNA replication, these enzymes are involved in the processing of Okazaki fragments, whereas in DNA repair, they function to excise damaged DNA fragments and correct recombinational mismatches
  • Exonucleases involved in these processes include DNA polymerases, including DNA pol delta and epsilon
  • DNA pol delta consists of two subunits-p125 which interacts directly with the sliding DNA clamp protein PCNA, and p50
  • DNA pol delta can be regulated by cell cycle proteins
  • DNA pol epsilon is a multiple subunit enzyme, the catalytic subunit of which is encoded by the POL2 gene
  • The exact reactions catalyzed by DNA pol delta and epsilon on leading and lagging strands have not yet been elucidated.

Compare Similar Items

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Thermo Scientific

PIPA5103788

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Antigen:
POLE2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
POLE2

Gene Alias:
DNA pol epsilon2; DNA pol epsilonB; DNA polymerase epsilon 2, accessory subunit; DNA polymerase epsilon small subunit; DNA polymerase epsilon subunit 2; DNA polymerase epsilon subunit B; DNA polymerase epsilon, subunit 2; DNA polymerase II subunit 2; DNApol epsilon2; DNApol epsilonB; DPE2; POLE2; polymerase (DNA directed), epsilon 2 (p59 subunit); polymerase (DNA directed), epsilon 2, accessory subunit; polymerase (DNA) epsilon 2, accessory subunit

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18974, 5427

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O54956, P56282

Gene Symbols:
POLE2

Immunogen:
A synthesized peptide derived from human POLE2(Accession P56282), corresponding to amino acid residues L477-F527.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5103791

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Antigen:
POLG

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
POLG

Gene Alias:
AA409516; DNA polymerase gamma; DNA polymerase gamma subunit 1 (Mitochondrial DNA polymerase catalytic subunit) (PolG-alpha); DNA polymerase gamma, catalytic subunit; DNA polymerase subunit gamma-1; DNA-directed DNA polymerase gamma; FLJ27114; MDP1; Mip1; MIRAS; Mitochondrial DNA polymerase catalytic subunit; mitochondrial DNA polymerase gamma; mitochondrial DNA polymerase gamma catalytic subunit; mitochondrial DNA polymerase-gamma; mitochondrial polymerase gamma; MTDPS4A; MTDPS4B; PEO; Pol gamma; Polg; POLG1; POLGA; PolG-alpha; polymerase (DNA directed), gamma; polymerase (DNA) gamma, catalytic subunit; polymerase, gamma; SANDO; SCAE; truncated mitochondrial DNA polymerase gamma catalytic subunit

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18975, 5428, 85472

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P54098, P54099, Q9QYV8

Gene Symbols:
POLG

Immunogen:
A synthesized peptide derived from human POLG(Accession P54098), corresponding to amino acid residues Y452-K502.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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Thermo Scientific

PIPA5103795

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Antigen:
ZNRD1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ZNRD1

Gene Alias:
1110014N07Rik; DNA-directed RNA polymerase I subunit RPA12; HTEX6; HTEX-6; hZR14; nuclear RNA polymerase I small specific subunit; nuclear RNA polymerase I small specific subunit Rpa12 like; RNA polymerase I small specific subunit Rpa12; Rpa12; Tctex6; tctex-6; TEX6; transcription-associated zinc ribbon protein; zinc ribbon domain containing 1; zinc ribbon domain containing, 1; zinc ribbon domain-containing protein 1; ZNRD1; ZR14

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
30834, 361784, 66136

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q6MFY5, Q791N7, Q9P1U0

Gene Symbols:
ZNRD1

Immunogen:
A synthesized peptide derived from human ZNRD1(Accession Q9P1U0), corresponding to amino acid residues M68-C118.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5103796

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Antigen:
TWISTNB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TWISTNB

Gene Alias:
2410173G11; 2810024J17Rik; D16Wsu83e; DNA-directed RNA polymerase I subunit RPA43; POLR1F; RNA polymerase I subunit F; twist basic helix-loop-helix transcription factor 1 neighbor; TWIST neighbor; twist neighbor protein; TWISTNB

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
221830

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q3B726

Gene Symbols:
TWISTNB

Immunogen:
A synthesized peptide derived from human TWISTNB(Accession Q3B726), corresponding to amino acid residues E272-T322.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG