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PIPA5103836

eIF3a Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5103836-Each-of-1 In Stock ₹ 44,705.10

PIPA5103836 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

eIF3a

Classification

Polyclonal

Conjugate

Unconjugated

Gene

EIF3A

Gene Alias

150/170; A830012B05Rik; Centrosomin; centrosomin homolog; Csma; cytoplasmic protein p167; Eif3; eIF3 p167; eIF3 p180; eIF3 p185; EIF3, p180 subunit; eIF3a; eIF3a {ECO:0000255; eIF3-p170; EIF3S10; eIF-3-theta; eIF3-theta; eIF-3-theta {ECO:0000255; eukaryotic translation initiation factor 3 subunit 10; EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 10 (EIF-3 THETA) (EIF3 P167) (EIF3 P180) (EIF3 P185) (P162 PROTEIN) (CENTROSOMIN); eukaryotic translation initiation factor 3 subunit 10 {ECO:0000255; eukaryotic translation initiation factor 3 subunit A; eukaryotic translation initiation factor 3 subunit A {ECO:0000255; eukaryotic translation initiation factor 3, subunit 10 (theta); eukaryotic translation initiation factor 3, subunit 10 (theta, 150/170kD); eukaryotic translation initiation factor 3, subunit 10 (theta, 170kD); eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa; eukaryotic translation initiation factor 3, subunit 10, 170kD; eukaryotic translation initi

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

13669, 292148, 8661

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P23116, Q14152, Q1JU68

Gene Symbols

EIF3A

Immunogen

A synthesized peptide derived from human EIF3A(Accession Q14152), corresponding to amino acid residues D1271-V1321.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • Antibody detects endogenous levels of total EIF3A
  • RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:17581632, PubMed:25849773)
  • The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC)
  • The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition
  • The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632, PubMed:11169732)
  • The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773, PubMed:27462815)
  • [UniProt]

Compare Similar Items

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Img

Thermo Scientific

PIPA5103836

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Antigen:
eIF3a
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
EIF3A
Gene Alias:
150/170; A830012B05Rik; Centrosomin; centrosomin homolog; Csma; cytoplasmic protein p167; Eif3; eIF3 p167; eIF3 p180; eIF3 p185; EIF3, p180 subunit; eIF3a; eIF3a {ECO:0000255; eIF3-p170; EIF3S10; eIF-3-theta; eIF3-theta; eIF-3-theta {ECO:0000255; eukaryotic translation initiation factor 3 subunit 10; EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 10 (EIF-3 THETA) (EIF3 P167) (EIF3 P180) (EIF3 P185) (P162 PROTEIN) (CENTROSOMIN); eukaryotic translation initiation factor 3 subunit 10 {ECO:0000255; eukaryotic translation initiation factor 3 subunit A; eukaryotic translation initiation factor 3 subunit A {ECO:0000255; eukaryotic translation initiation factor 3, subunit 10 (theta); eukaryotic translation initiation factor 3, subunit 10 (theta, 150/170kD); eukaryotic translation initiation factor 3, subunit 10 (theta, 170kD); eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa; eukaryotic translation initiation factor 3, subunit 10, 170kD; eukaryotic translation initi
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
13669, 292148, 8661
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P23116, Q14152, Q1JU68
Gene Symbols:
EIF3A
Immunogen:
A synthesized peptide derived from human EIF3A(Accession Q14152), corresponding to amino acid residues D1271-V1321.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG

Img

Thermo Scientific

PIPA5103840

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Antigen:
KHSRP
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
KHSRP
Gene Alias:
6330409F21Rik; Far upstream element-binding protein 2; FBP2; Fubp2; FUSE binding protein 2; FUSE-binding protein 2; KH type-splicing regulatory protein; KHE3; KHSRP; KH-type splicing regulatory protein; KH-type splicing regulatory protein (FUSE binding protein 2); KSRP; MAP2 RNA trans-acting protein 1; MAP2 RNA trans-acting protein MARTA1; MARTA1; p75
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16549, 171137, 8570
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q3U0V1, Q92945, Q99PF5
Gene Symbols:
KHSRP
Immunogen:
A synthesized peptide derived from human KHSRP(Accession Q92945), corresponding to amino acid residues I84-L134.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG

Img

Thermo Scientific

PIPA5103841

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Antigen:
Fibulin 1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Fbln1
Gene Alias:
Basement-membrane protein 90; BM-90; BM-90/fibulin extracellular matrix glyroprotein; extracellular matrix; extracellular matrix and blood protein; FBLN; Fbln1; fbln1c; fbln1d; FIBL1; FIBL-1; fibulin 1; fibulin 1C; fibulin 1D; Fibulin1; fibulin-1; fibulin-1 C varible region; fibulin-1 D; LOW QUALITY PROTEIN: fibulin-1; PP213; wu:fc52c06
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14114, 2192, 315191
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P23142, Q08879
Gene Symbols:
Fbln1
Immunogen:
A synthesized peptide derived from human FBLN1(Accession P23142), corresponding to amino acid residues S316-P366.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG

Img

Thermo Scientific

PIPA5103845

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Antigen:
FOXD4L5
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
FOXD4L5
Gene Alias:
bA15J10.2; forkhead box D4-like 5; forkhead box protein D4-like 5; FOXD4L5; FOXD4-like 5
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
653427
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q5VV16
Gene Symbols:
FOXD4L5
Immunogen:
A synthesized peptide derived from human FOXD4L5(Accession Q5VV16), corresponding to amino acid residues P233-K283.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG