PIPA5103887

HLA-DMB Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5103887-Each-of-1 In Stock ₹ 44,705.10

PIPA5103887 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

HLA-DMB

Classification

Polyclonal

Conjugate

Unconjugated

Gene

HLA-DMB

Gene Alias

class II histocompatibility antigen, M beta chain; D6S221E; DAAP-27A1.4; DMB; HLA class II histocompatibility antigen, DM beta chain; HLA-DMB; major histocompatibility complex, class II, DM beta; MHC class II antigen DMB; MHC class II antigen HLA-DM beta chain; MHC class II HLA-DMB; really interesting new gene 7 protein; RING7

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3109

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P28068

Gene Symbols

HLA-DMB

Immunogen

A synthesized peptide derived from human HLA-DMB(Accession P28068), corresponding to amino acid residues G229-S263.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Antibody detects endogenous levels of total HLA-DMB
  • HLA-DMB (major histocompatibility complex, class II, DM beta), also known as D6S221E, RING7, HLA-DM histocompatibility type, beta chain, HLADMB or RING7, is a protein that in humans is encoded by the HLA-DMB gene
  • The HLA-DMB gene is mapped on 6p21.32
  • HLA-DMB belongs to the HLA class II beta chain paralogues
  • This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane
  • It is located in intracellular vesicles
  • DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site
  • Class II molecules are expressed in antigen presenting cells
  • The beta chain is approximately 26-28 kDa and its gene contains 6 exons
  • HLA-DMA and -DMB appear to encode subunits of a functional heterodimer that is critical in the pathway of class II antigen presentation
  • HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

Compare Similar Items

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Img

Thermo Scientific

PIPA5103887

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Antigen:
HLA-DMB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HLA-DMB

Gene Alias:
class II histocompatibility antigen, M beta chain; D6S221E; DAAP-27A1.4; DMB; HLA class II histocompatibility antigen, DM beta chain; HLA-DMB; major histocompatibility complex, class II, DM beta; MHC class II antigen DMB; MHC class II antigen HLA-DM beta chain; MHC class II HLA-DMB; really interesting new gene 7 protein; RING7

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3109

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P28068

Gene Symbols:
HLA-DMB

Immunogen:
A synthesized peptide derived from human HLA-DMB(Accession P28068), corresponding to amino acid residues G229-S263.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5103888

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Antigen:
HLA-DQB2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HLA-DQB2

Gene Alias:
DV19.1 (major histocompatibility complex, class II, DQ beta 2 (HLA-DXB)); HLA class II histocompatibility antigen, DQ beta 2 chain; HLA class II histocompatibility antigen, DX beta chain; HLA-DQB1; HLA-DQB2; HLA-DXB; major histocompatibility complex, class II, DQ beta 1; major histocompatibility complex, class II, DQ beta 2; MHC class II antigen DQB2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3120

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P05538

Gene Symbols:
HLA-DQB2

Immunogen:
A synthesized peptide derived from human HLA-DQB2(Accession P05538), corresponding to amino acid residues G233-H268.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5103889

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Antigen:
HOXB1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Hoxb1

Gene Alias:
HCFP3, homeo box B1, homeobox B1, homeobox protein Hox-2.9, Homeobox protein Hox-2I, homeobox protein Hox-B1, HOX2, Hox-2.9, Hox-29, HOX2I, Hoxb1, Hoxb-1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15407, 3211

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P14653, P17919

Gene Symbols:
Hoxb1

Immunogen:
A synthesized peptide derived from human HOXB1(Accession P14653), corresponding to amino acid residues S78-G128.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5103890

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Antigen:
HOXB3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HOXB3

Gene Alias:
homeo box 2G; homeo box B3; homeobox B3; homeobox protein Hox-2.7; Homeobox protein Hox-2G; homeobox protein Hox-B3; Homeobox protein MH-23; HOX2; Hox-2.7; HOX2G; HOXB3; Hoxb-3

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15410, 303488, 3213

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P09026, P14651

Gene Symbols:
HOXB3

Immunogen:
A synthesized peptide derived from human HOXB3(Accession P14651), corresponding to amino acid residues A359-D409.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG