PIPA5103914

MED11 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5103914-Each-of-1 In Stock ₹ 43,592.82

PIPA5103914 - Each of 1

₹ 43,592.82

In Stock

Quantity

1

Base Price: ₹ 43,592.82

GST (18%): ₹ 7,846.708

Total Price: ₹ 51,439.528

Antigen

MED11

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MED11

Gene Alias

1110030J09Rik; AI465144; AW545069; HSPC296; MED11; Mediator complex subunit 11; mediator of RNA polymerase II transcription subunit 11; mediator of RNA polymerase II transcription, subunit 11 homolog; RGD1563202

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

287456, 400569, 66172

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q9D8C6, Q9P086

Gene Symbols

MED11

Immunogen

A synthesized peptide derived from human MED11(Accession Q9P086), corresponding to amino acid residues A13-L63.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • Antibody detects endogenous levels of total MED11
  • In mammalian cells, transcription is regulated in part by high molecular weight co-activating complexes that mediate signals between transcriptional activators and RNA polymerase II (Pol II)
  • The mediator complex is one such multiprotein structure that functions as a bridge between regulatory proteins and Pol II, thereby regulating Pol II-dependent transcription
  • Med11 (mediator complex subunit 11) is a 117 amino acid nuclear protein and component of the mediator complex
  • The gene encoding Med11 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes
  • Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1
  • Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome
  • Like p53, BRCA1 is directly involved in DNA repair, and is associated with predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.

Compare Similar Items

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Img

Thermo Scientific

PIPA5103914

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Antigen:
MED11

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MED11

Gene Alias:
1110030J09Rik; AI465144; AW545069; HSPC296; MED11; Mediator complex subunit 11; mediator of RNA polymerase II transcription subunit 11; mediator of RNA polymerase II transcription, subunit 11 homolog; RGD1563202

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
287456, 400569, 66172

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9D8C6, Q9P086

Gene Symbols:
MED11

Immunogen:
A synthesized peptide derived from human MED11(Accession Q9P086), corresponding to amino acid residues A13-L63.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5103915

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Antigen:
PCQAP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MED15

Gene Alias:
A230074L19Rik; Activator-recruited cofactor 105 kDa component; activator-recruited cofactor, 105-kD; ARC105; AW536074; CAG7A; CTG repeat protein 7a; CTG7A; DKFZp686A2214; DKFZp762B1216; FLJ42282; FLJ42935; MED15; Mediator complex subunit 15; mediator of RNA polymerase II transcription subunit 15; mPcqap; PC2 (positive cofactor 2, multiprotein complex) glutamine/Q-rich-associated protein; PC2 glutamine/Q-rich-associated protein; PC2-glutamine-rich-associated protein; PCQAP; Positive cofactor 2 glutamine/Q-rich-associated protein; positive cofactor 2, glutamine/Q-rich-associated protein; positive cofactor 2, multiprotein complex, glutamine/Q-rich-associated protein; TIG1; TIG-1; TNRC7; TPA inducible gene-1; TPA inducible protein; TPA-inducible gene 1 protein; trinucleotide repeat containing 7; trinucleotide repeat-containing gene 7 protein

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
360743, 51586, 94112

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q924H2, Q96RN5

Gene Symbols:
MED15

Immunogen:
A synthesized peptide derived from human MED15(Accession Q96RN5), corresponding to amino acid residues C698-F748.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5103916

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Antigen:
MED22

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MED22

Gene Alias:
AW212655; AW558812; MED22; MED24; Mediator complex subunit 22; mediator of RNA polymerase II transcription subunit 22; MGC48682; RGD1564893; si:ch73-278c20.1; si:dkey-226m8.2; surf5; Surf-5; surfeit 5; surfeit 5 isoform b; surfeit gene 5; surfeit locus protein 5; wu:fj45h07; zgc:86721

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20933, 499762, 6837

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
A0JPN6, Q15528, Q62276

Gene Symbols:
MED22

Immunogen:
A synthesized peptide derived from human MED22(Accession Q15528), corresponding to amino acid residues L119-P169.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5103917

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Antigen:
MED28

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MED28

Gene Alias:
1500003D12Rik; AI451633; AU045690; EG1; endothelial-derived; endothelial-derived gene 1; endothelial-derived protein 1; Fksg20; Magicin; Med28; Mediator complex subunit 28; mediator of RNA polymerase II transcription subunit 28; mediator of RNA polymerase II transcription, subunit 28 homolog; merlin and Grb2-interacting cytoskeletal protein; RGD1305875; Tumor angiogenesis marker EG-1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
305391, 66999, 80306

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P68943, Q920D3, Q9H204

Gene Symbols:
MED28

Immunogen:
A synthesized peptide derived from human MED28(Accession Q9H204), corresponding to amino acid residues T43-C93.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG