PIPA5103928
MPP8 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5103928-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5103928 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
MPP8
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MPHOSPH8
Gene Alias
1500035L22Rik; 4930548G07Rik; Ab2-008; AU040635; HSMPP8; M-phase phosphoprotein 8; M-phase phosphoprotein, mpp; M-phase phosphoprotein, mpp8; Mphosph8; MPP8; RGD1305133; TWA3; Two hybrid-associated protein 3 with RanBPM
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
290270, 54737, 75339
Content And Storage
-20°C
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
G3V8T1, Q3TYA6, Q99549
Gene Symbols
MPHOSPH8
Immunogen
A synthesized peptide derived from human MPHOSPH8(Accession Q99549), corresponding to amino acid residues M318-R368.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Description
- Antibody detects endogenous levels of total MPHOSPH8
- Heterochromatin component that specifically recognizes and binds methylated 'Lys-9' of histone H3 (H3K9me) and promotes recruitment of proteins that mediate epigenetic repression (PubMed:20871592, PubMed:26022416)
- Mediates recruitment of the HUSH complex to H3K9me3 sites: the HUSH complex is recruited to genomic loci rich in H3K9me3 and is required to maintain transcriptional silencing by promoting recruitment of SETDB1, a histone methyltransferase that mediates further deposition of H3K9me3, as well as MORC2 (PubMed:26022416, PubMed:28581500)
- Binds H3K9me and promotes DNA methylation by recruiting DNMT3A to target CpG sites; these can be situated within the coding region of the gene (PubMed:20871592)
- Mediates down-regulation of CDH1 expression (PubMed:20871592)
- Also represses L1 retrotransposons in collaboration with MORC2 and, probably, SETDB1, the silencing is dependent of repressive epigenetic modifications, such as H3K9me3 mark
- Silencing events often occur within introns of transcriptionally active genes, and lead to the down-regulation of host gene expression (PubMed:29211708)
- The HUSH complex is also involved in the silencing of unintegrated retroviral DNA by being recruited by ZNF638: some part of the retroviral DNA formed immediately after infection remains unintegrated in the host genome and is transcriptionally repressed (PubMed:30487602)
- [UniProt]
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Antigen: MPP8
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MPHOSPH8
Gene Alias: 1500035L22Rik; 4930548G07Rik; Ab2-008; AU040635; HSMPP8; M-phase phosphoprotein 8; M-phase phosphoprotein, mpp; M-phase phosphoprotein, mpp8; Mphosph8; MPP8; RGD1305133; TWA3; Two hybrid-associated protein 3 with RanBPM
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 290270, 54737, 75339
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: G3V8T1, Q3TYA6, Q99549
Gene Symbols: MPHOSPH8
Immunogen: A synthesized peptide derived from human MPHOSPH8(Accession Q99549), corresponding to amino acid residues M318-R368.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
MPP8
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MPHOSPH8
Gene Alias:
1500035L22Rik; 4930548G07Rik; Ab2-008; AU040635; HSMPP8; M-phase phosphoprotein 8; M-phase phosphoprotein, mpp; M-phase phosphoprotein, mpp8; Mphosph8; MPP8; RGD1305133; TWA3; Two hybrid-associated protein 3 with RanBPM
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
290270, 54737, 75339
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
G3V8T1, Q3TYA6, Q99549
Gene Symbols:
MPHOSPH8
Immunogen:
A synthesized peptide derived from human MPHOSPH8(Accession Q99549), corresponding to amino acid residues M318-R368.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: MUC4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MUC4
Gene Alias: 4933405I11Rik; Ascites sialoglycoprotein; Ascites sialoglycoprotein 1; Ascites sialoglycoprotein 2; ASGP; ASGP1; ASGP-1; ASGP-2; HSA276359; MUC4; MUC-4; mucin 4; mucin 4, ASGP; mucin 4, cell surface associated; mucin 4, tracheobronchial; Mucin4; mucin-4; Mucin-4 alpha chain; Mucin-4 beta chain; Pancreatic adenocarcinoma mucin; pre-sialomucin complex; Psmc; sialomucin ascites sialoglycoprotein-1; sialomucin complex; testis mucin; Tracheobronchial mucin
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4585
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q99102
Gene Symbols: MUC4
Immunogen: A synthesized peptide derived from human MUC4(Accession Q99102), corresponding to amino acid residues S1581-I1631.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
MUC4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MUC4
Gene Alias:
4933405I11Rik; Ascites sialoglycoprotein; Ascites sialoglycoprotein 1; Ascites sialoglycoprotein 2; ASGP; ASGP1; ASGP-1; ASGP-2; HSA276359; MUC4; MUC-4; mucin 4; mucin 4, ASGP; mucin 4, cell surface associated; mucin 4, tracheobronchial; Mucin4; mucin-4; Mucin-4 alpha chain; Mucin-4 beta chain; Pancreatic adenocarcinoma mucin; pre-sialomucin complex; Psmc; sialomucin ascites sialoglycoprotein-1; sialomucin complex; testis mucin; Tracheobronchial mucin
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4585
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q99102
Gene Symbols:
MUC4
Immunogen:
A synthesized peptide derived from human MUC4(Accession Q99102), corresponding to amino acid residues S1581-I1631.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: MUC7
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MUC7
Gene Alias: apo-MG2; MG2; MUC7; MUC-7; mucin 7, salivary; mucin 7, secreted; mucin-7; Salivary mucin-7
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4589
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q8TAX7
Gene Symbols: MUC7
Immunogen: A synthesized peptide derived from human MUC7(Accession Q8TAX7), corresponding to amino acid residues S62-P112.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
MUC7
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MUC7
Gene Alias:
apo-MG2; MG2; MUC7; MUC-7; mucin 7, salivary; mucin 7, secreted; mucin-7; Salivary mucin-7
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4589
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q8TAX7
Gene Symbols:
MUC7
Immunogen:
A synthesized peptide derived from human MUC7(Accession Q8TAX7), corresponding to amino acid residues S62-P112.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: ABCC6
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ABCC6
Gene Alias: ABC34; Abcc1b; ABCC6; Anthracycline resistance-associated protein; ARA; ATP binding cassette subfamily C member 6; ATP-binding cassette sub-family C member 6; ATP-binding cassette, subfamily C (CFTR/MRP), member 6; ATP-binding cassette, sub-family C (CFTR/MRP), member 6; ATP-binding cassette, sub-family C, member 6; DCC; dyscalc; Dyscalc1; EST349056; GACI2; liver multidrug resistance-associated protein 6; Mlp1; MLP-1; MOATE; MOAT-E; Mrp6; MRP-like protein 1; Multidrug resistance-associated protein 6; multidrug resistance-associated protein-6; multi-specific organic anion transporter E; PXE; PXE1; URG7; URG7 protein; multidrug resistance-associated protein 6
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 27421, 368, 81642
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: O88269, O95255, Q9R1S7
Gene Symbols: ABCC6
Immunogen: A synthesized peptide derived from human ABCC6(Accession O95255), corresponding to amino acid residues L316-F366.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ABCC6
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ABCC6
Gene Alias:
ABC34; Abcc1b; ABCC6; Anthracycline resistance-associated protein; ARA; ATP binding cassette subfamily C member 6; ATP-binding cassette sub-family C member 6; ATP-binding cassette, subfamily C (CFTR/MRP), member 6; ATP-binding cassette, sub-family C (CFTR/MRP), member 6; ATP-binding cassette, sub-family C, member 6; DCC; dyscalc; Dyscalc1; EST349056; GACI2; liver multidrug resistance-associated protein 6; Mlp1; MLP-1; MOATE; MOAT-E; Mrp6; MRP-like protein 1; Multidrug resistance-associated protein 6; multidrug resistance-associated protein-6; multi-specific organic anion transporter E; PXE; PXE1; URG7; URG7 protein; multidrug resistance-associated protein 6
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
27421, 368, 81642
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
O88269, O95255, Q9R1S7
Gene Symbols:
ABCC6
Immunogen:
A synthesized peptide derived from human ABCC6(Accession O95255), corresponding to amino acid residues L316-F366.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG