PIPA5103957

UNC5A Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5103957-Each-of-1 In Stock ₹ 43,592.82

PIPA5103957 - Each of 1

₹ 43,592.82

In Stock

Quantity

1

Base Price: ₹ 43,592.82

GST (18%): ₹ 7,846.708

Total Price: ₹ 51,439.528

Antigen

UNC5A

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Unc5a

Gene Alias

Kiaa1976; mKIAA1976; netrin receptor UNC5A; netrin receptor Unc5h1; protein unc-5 homolog 1; Protein unc-5 homolog A; transmembrane receptor Unc5H1; unc5 (C.elegans homolog) a; unc5 homolog 1; unc-5 homolog 1; unc-5 homolog A; unc-5 homolog A (C. elegans); unc-5 netrin receptor A; UNC5A; Unc5h1; UNC5H1FLJ16449

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

107448, 60629, 90249

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O08721, Q6ZN44, Q8K1S4

Gene Symbols

Unc5a

Immunogen

A synthesized peptide derived from human UNC5A(Accession Q6ZN44), corresponding to amino acid residues S356-G406.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total UNC5A
  • The UNC5H family of proteins act as transmembrane receptors for netrin-1 and play a crucial role in axon guidance and migration of neural cells
  • Additionally, when cleaved by a caspase to produce an intracellular fragment containing a death domain, UNC5H receptors induce apoptosis
  • This activity is blocked by the binding of netrin-1
  • In the absence of netrin-1, UNC5H receptors act as tumor suppressors by inhibiting anchorage-independent growth and invasion, but mutation of these receptors provides a potential mechanism for tumorigenicity
  • The expression of UNC5H receptors is downregulated in multiple carcinomas, including colorectal, breast, ovary, uterus, stomach, lung and kidney cancers
  • UNC5H1, also known as UNC5HA (unc-5 homolog A), is a member of the UNC5H family of proteins and is localized to the cell membrane
  • Three isoforms of UNC5H1 exist due to alternative splicing events.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA5103957

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Antigen:
UNC5A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Unc5a

Gene Alias:
Kiaa1976; mKIAA1976; netrin receptor UNC5A; netrin receptor Unc5h1; protein unc-5 homolog 1; Protein unc-5 homolog A; transmembrane receptor Unc5H1; unc5 (C.elegans homolog) a; unc5 homolog 1; unc-5 homolog 1; unc-5 homolog A; unc-5 homolog A (C. elegans); unc-5 netrin receptor A; UNC5A; Unc5h1; UNC5H1FLJ16449

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
107448, 60629, 90249

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O08721, Q6ZN44, Q8K1S4

Gene Symbols:
Unc5a

Immunogen:
A synthesized peptide derived from human UNC5A(Accession Q6ZN44), corresponding to amino acid residues S356-G406.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5103958

--


Antigen:
NGRN

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NGRN

Gene Alias:
AW552001; DSC92; FI58G; FI58Gm; HT020; mesenchymal stem cell protein DSC92; m-Neugrin; Neugrin; neugrin, neurite outgrowth associated; neurite outgrowth associated protein; neurite outgrowth-associated protein; NGRN; Spinal cord-derived protein FI58G

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
51335

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9NPE2

Gene Symbols:
NGRN

Immunogen:
A synthesized peptide derived from human NGRN(Accession Q9NPE2), corresponding to amino acid residues V17-Q67.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5103959

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Antigen:
Neurensin 2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NRSN2

Gene Alias:
C20orf98; dJ1103G7.6; FLJ23329; Gm123; neurensin 2; Neurensin2; Neurensin-2; NRSN2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
80023

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9GZP1

Gene Symbols:
NRSN2

Immunogen:
A synthesized peptide derived from human NRSN2(Accession Q9GZP1), corresponding to amino acid residues E167-S204.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5103961

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Antigen:
NBPF3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NBPF3

Gene Alias:
AE2; L7; NBPF3; Neuroblastoma breakpoint family member 3; neuroblastoma breakpoint family, member 3; Protein AE2; Protein SHIIIa4

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
84224

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9H094

Gene Symbols:
NBPF3

Immunogen:
A synthesized peptide derived from human NBPF3(Accession Q9H094), corresponding to amino acid residues S480-F530.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG