PIPA5103976

DFNA5 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5103976-Each-of-1 In Stock ₹ 44,705.10

PIPA5103976 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

DFNA5

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Gsdme

Gene Alias

2310037D07Rik; 4932441K13Rik; deafness, autosomal dominant 5; deafness, autosomal dominant 5 (human); deafness, autosomal dominant 5 homolog; Dfna5; DFNA5, deafness associated tumor suppressor; Dfna5h; EG14210; Fin15; Gasdermin-E; Gasdermin-E, C-terminal; Gasdermin-E, N-terminal; GSDME; GSDME-CT; GSDME-NT; ICERE1; ICERE-1; Inversely correlated with estrogen receptor expression 1; nonsyndromic hearing impairment protein; non-syndromic hearing impairment protein 5; Non-syndromic hearing impairment protein 5 homolog

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1687, 54722

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O60443, Q9Z2D3

Gene Symbols

Gsdme

Immunogen

A synthesized peptide derived from human DFNA5(Accession O60443), corresponding to amino acid residues L403-A453.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Description

  • Antibody detects endogenous levels of total DFNA5/GSDME
  • DFNA5 (deafness, autosomal dominant 5), also known as ICERE-1, is a 496 amino acid protein that is expressed in cochlea tissue, as well as in placenta, brain, heart, liver, lung and pancreas as two alternatively spliced isoforms, designated short and long
  • Defects in the gene encoding DFNA5 are the cause of non-syndromic sensorineural deafness autosomal dominant type 5 (DFNA5), a form of sensorineural hearing loss that results from damage to one of various structures that receive sound information in the brain
  • The gene encoding DFNA5 maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome
  • Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.

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Img

Thermo Scientific

PIPA5103976

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Antigen:
DFNA5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Gsdme

Gene Alias:
2310037D07Rik; 4932441K13Rik; deafness, autosomal dominant 5; deafness, autosomal dominant 5 (human); deafness, autosomal dominant 5 homolog; Dfna5; DFNA5, deafness associated tumor suppressor; Dfna5h; EG14210; Fin15; Gasdermin-E; Gasdermin-E, C-terminal; Gasdermin-E, N-terminal; GSDME; GSDME-CT; GSDME-NT; ICERE1; ICERE-1; Inversely correlated with estrogen receptor expression 1; nonsyndromic hearing impairment protein; non-syndromic hearing impairment protein 5; Non-syndromic hearing impairment protein 5 homolog

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1687, 54722

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O60443, Q9Z2D3

Gene Symbols:
Gsdme

Immunogen:
A synthesized peptide derived from human DFNA5(Accession O60443), corresponding to amino acid residues L403-A453.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5103977

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Antigen:
NUP133

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NUP133

Gene Alias:
133 kDa nucleoporin; hNUP133; mermaid; Nuclear pore complex protein Nup133; nucleoporin 133; nucleoporin 133kD; nucleoporin 133kDa; nucleoporin Nup133; NUP133

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
234865, 292085, 55746

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q8R0G9, Q8WUM0

Gene Symbols:
NUP133

Immunogen:
A synthesized peptide derived from human NUP133(Accession Q8WUM0), corresponding to amino acid residues L857-E907.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5103979

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Antigen:
NUP205

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NUP205

Gene Alias:
205 kDa nucleoporin; 3830404O05Rik; AV248391; C7orf14; KIAA0225; mKIAA0225; NPHS13; Nuclear pore complex protein Nup205; nucleoporin 205; nucleoporin 205kDa; nucleoporin Nup205; NUP205

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23165, 362335, 70699

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q92621

Gene Symbols:
NUP205

Immunogen:
A synthesized peptide derived from human NUP205(Accession Q92621), corresponding to amino acid residues L1129-R1179.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5103980

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Antigen:
NUP88

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NUP88

Gene Alias:
88 kDa nuclear pore complex protein; 88 kDa nucleoporin; karyoporin; nuclear pore complex protein 88; nuclear pore complex protein Nup88; nucleoporin 88; nucleoporin 88kDa; nucleoporin Nup84; Nucleoporin Nup88; Nup84; NUP88; Prei2; preimplantation protein 2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19069, 4927

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q8CEC0, Q99567

Gene Symbols:
NUP88

Immunogen:
A synthesized peptide derived from human NUP88(Accession Q99567), corresponding to amino acid residues D436-T486.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG