PIPA5104129

SRPK2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5104129-Each-of-1 In Stock ₹ 44,705.10

PIPA5104129 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

SRPK2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SRPK2

Gene Alias

AW226533; AW492537; AW547358; H_RG152G17.1a; H_RG152G17.1b; mSRPK2; serine kinase SRPK2; serine/arginine-rich protein specific kinase 2; serine/arginine-rich protein-specific kinase 2; serine/arginine-rich splicing factor kinase 2; serine/threonine-protein kinase SRPK2; SFRS protein kinase 2; SFRSK2; SR protein kinase 2; SRPK2; SR-protein-specific kinase 2; SRSF protein kinase 2; SRSF protein kinase 2 C-terminal; SRSF protein kinase 2 N-terminal; Wbp6; WUGSC:H_RG152G17.1a; WW domain binding protein 6

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20817, 296753, 6733

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O54781, P78362

Gene Symbols

SRPK2

Immunogen

A synthesized peptide derived from human SRPK2(Accession P78362), corresponding to amino acid residues S454-A504.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG

Description

  • Antibody detects endogenous levels of total SRPK2
  • SRPK2, along with SRPK1, is most likely the cellular protein kinase mediating HBV core protein phosphorylation during viral infection
  • It therefore represents an important host cell target for therapeutic intervention in HBV infection
  • Promotes neuronal apoptosis by up-regulating cyclin-D1 (CCND1) expression
  • This is done by the phosphorylation of SRSF2, leading to the suppression of p53/TP53 phosphorylation thereby relieving the repressive effect of p53/TP53 on cyclin-D1 (CCND1) expression
  • Phosphorylates ACIN1, and redistributes it from the nuclear speckles to the nucleoplasm, resulting in cyclin A1 but not cyclin A2 up-regulation
  • Plays an essential role in spliceosomal B complex formation via the phosphorylation of DDX23/PRP28
  • Plays a negative role in the regulation of HBV replication through a mechanism not involving the phosphorylation of the core protein but by reducing the packaging efficiency of the pregenomic RNA (pgRNA) without affecting the formation of the viral core particles .

Compare Similar Items

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Img

Thermo Scientific

PIPA5104129

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Antigen:
SRPK2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SRPK2

Gene Alias:
AW226533; AW492537; AW547358; H_RG152G17.1a; H_RG152G17.1b; mSRPK2; serine kinase SRPK2; serine/arginine-rich protein specific kinase 2; serine/arginine-rich protein-specific kinase 2; serine/arginine-rich splicing factor kinase 2; serine/threonine-protein kinase SRPK2; SFRS protein kinase 2; SFRSK2; SR protein kinase 2; SRPK2; SR-protein-specific kinase 2; SRSF protein kinase 2; SRSF protein kinase 2 C-terminal; SRSF protein kinase 2 N-terminal; Wbp6; WUGSC:H_RG152G17.1a; WW domain binding protein 6

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20817, 296753, 6733

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O54781, P78362

Gene Symbols:
SRPK2

Immunogen:
A synthesized peptide derived from human SRPK2(Accession P78362), corresponding to amino acid residues S454-A504.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5104132

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Antigen:
SERPINB10

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SERPINB10

Gene Alias:
9830131G07; BB233602; Bomapin; peptidase inhibitor 10; PI10; PI-10; protease inhibitor 10 (ovalbumin type, bomapin); serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 10; serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 10, pseudogene; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 10; serpin B10; serpin family B member 10; serpin peptidase inhibitor, clade B (ovalbumin), member 10; SERPINB10; Serpinb10-ps; TGF-beta-repressible serine proteinase inhibitor; transforming growth factor beta repressible serpin; Trespin

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
241197, 266775, 5273

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P48595, Q8K1K6, Q8K3K4

Gene Symbols:
SERPINB10

Immunogen:
A synthesized peptide derived from human SERPINB10(Accession P48595), corresponding to amino acid residues I182-E232.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5104133

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Antigen:
SCML2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SCML2

Gene Alias:
4932420G07Rik; Scm polycomb group protein like 2; SCML2; sex comb on midleg-like 2 (Drosophila); sex comb on midleg-like protein 2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10389, 107815

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9UQR0

Gene Symbols:
SCML2

Immunogen:
A synthesized peptide derived from human SCML2(Accession Q9UQR0), corresponding to amino acid residues F448-R498.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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Thermo Scientific

PIPA5104137

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Antigen:
SH3TC2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SH3TC2

Gene Alias:
CMT4C; D430044G18Rik; KIAA1985; MNMN; PP12494; RGD1309038; SH3 domain and tetratricopeptide repeat-containing protein 2; SH3 domain and tetratricopeptide repeats 2; SH3 domain and tetratricopeptide repeats-containing protein 2; SH3TC2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
225608, 79628

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q80VA5, Q8TF17

Gene Symbols:
SH3TC2

Immunogen:
A synthesized peptide derived from human SH3TC2(Accession Q8TF17), corresponding to amino acid residues L1244-L1288.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG