PIPA5104340

cGAS Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5104340-Each-of-1 In Stock ₹ 44,705.10

PIPA5104340 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

cGAS

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CGAS

Gene Alias

C6orf150; h-cGAS; MB21D1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

115004

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q8N884

Gene Symbols

CGAS

Immunogen

A synthesized peptide derived from human MB21D1(Accession Q8N884), corresponding to amino acid residues E103-L153.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total C6orf150
  • cGAS (Cyclic GMP-AMP synthase) is a nucleotidyltransferase that catalyzes the formation of cyclic GMP-AMP (cGAMP) from ATP and GTP and plays a key role in innate immunity
  • Catalysis involves both the formation of 2', 5' phosphodiester linkage at the GpA step and the formation of 3', 5' phosphodiester linkage at the ApG step
  • This produces c[G(2',5')pA(3'5')p] responses
  • cGAS also binds cytosolic DNA directly, leading to the activation and synthesis of cGAMP
  • Then, a second messenger binds to and activates TMEM173/STING thereby triggering type-I interferon production
  • cGAS is also involved in innate immune sensorship of infection, detection of DNA from bacteria, response to cellular stress, DNA damage, and regulation of cellular senescence.

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Thermo Scientific

PIPA5104340

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Antigen:
cGAS

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CGAS

Gene Alias:
C6orf150; h-cGAS; MB21D1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
115004

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q8N884

Gene Symbols:
CGAS

Immunogen:
A synthesized peptide derived from human MB21D1(Accession Q8N884), corresponding to amino acid residues E103-L153.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5104341

--


Antigen:
CPLX3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cplx3

Gene Alias:
BC016632; complexin 3; complexin III; Complexin-3; CPLX3; CPX III; CpxIII; CPX-III; ERGIC-53L; ERGL; Lamn1l; lectin, mannose-binding, 1 like; Lman1l; Nbla11589; RGD1560104

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
235415, 501005, 594855

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q8R1B5, Q8WVH0

Gene Symbols:
Cplx3

Immunogen:
A synthesized peptide derived from human CPLX3(Accession Q8WVH0), corresponding to amino acid residues M1-Q48.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5104342

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Antigen:
DNAJB12

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DNAJB12

Gene Alias:
DJ10; DKFZp586B2023; DnaJ (Hsp40) homolog, subfamily B, member 12; DnaJ heat shock protein family (Hsp40) member B12; DnaJ homolog 10; dnaJ homolog subfamily B member 12; DnaJ subfamily B member 12-like protein; Dnajb12; LOW QUALITY PROTEIN: dnaJ homolog subfamily B member 12; mDj10

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
294513, 54788, 56709

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9NXW2, Q9QYI4

Gene Symbols:
DNAJB12

Immunogen:
A synthesized peptide derived from human DNAJB12(Accession Q9NXW2), corresponding to amino acid residues A147-D197.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5104344

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Antigen:
FAM195A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MCRIP2

Gene Alias:
9530058B02Rik; C16orf14; c349E10.1; FAM195A; family with sequence similarity 195 member A; family with sequence similarity 195, member A; MAPK regulated corepressor interacting protein 2; MAPK regulated co-repressor interacting protein 2; MCRIP2; Protein FAM195A

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
68241, 685545, 84331

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9BUT9, Q9CQB2

Gene Symbols:
MCRIP2

Immunogen:
A synthesized peptide derived from human MCRIP2(Accession Q9BUT9), corresponding to amino acid residues R15-R65.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG