PIPA5104444

RyR2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5104444-Each-of-1 In Stock ₹ 44,191.74

PIPA5104444 - Each of 1

₹ 44,191.74

In Stock

Quantity

1

Base Price: ₹ 44,191.74

GST (18%): ₹ 7,954.513

Total Price: ₹ 52,146.253

Antigen

RyR2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Ryr2

Gene Alias

9330127I20Rik; ARVC2; ARVD2; calcium release channel; cardiac muscle ryanodine receptor; Cardiac muscle ryanodine receptor-calcium release channel; cardiac ryanodine receptor 2; cardiac-type ryanodine receptor; hRYR-2; islet-type ryanodine receptor; kidney-type ryanodine receptor; Ryanodine receptor; ryanodine receptor 2; ryanodine receptor 2 (cardiac); ryanodine receptor 2, cardiac; ryanodine receptor type 2; ryanodine receptor type II; RyR; RYR2; RYR-2; Type 2 ryanodine receptor; VTSIP

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20191, 6262, 689560

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

B0LPN4, E9Q401, Q92736

Gene Symbols

Ryr2

Immunogen

A synthesized peptide derived from human RYR2(Accession Q92736), corresponding to amino acid residues M2782-T2832.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • Antibody detects endogenous levels of total RYR2
  • Dihydropyridine receptor (DHPR) is a surface membrane protein critical for the excitation-contraction coupling of striated muscle
  • DHPR and the sarcoplasmic reticulum ryanodine receptor (RyR) are two key components of the intracellular junctions, where depolarization of the surface membrane is converted into the release of Ca2+ from internal stores
  • The alpha1-subunit of the DHPR contains a cytoplasmic loop which is thought to be involved in the interactions with RyR
  • Phosphorylation of the DHPR alpha1-subunit is also thought to play a role in the functional interaction of DHPR and RyR
  • Mutation in DHPR alpha1 results in excitation-contraction uncoupling, leading to muscular dysgenesis, a complete inactivity in developing skeletal muscles
  • Cells that do not express RyR also lack excitation-contraction coupling and exhibit a severalfold reduction in Ca2+ current density.

Compare Similar Items

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Thermo Scientific

PIPA5104444

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Antigen:
RyR2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ryr2

Gene Alias:
9330127I20Rik; ARVC2; ARVD2; calcium release channel; cardiac muscle ryanodine receptor; Cardiac muscle ryanodine receptor-calcium release channel; cardiac ryanodine receptor 2; cardiac-type ryanodine receptor; hRYR-2; islet-type ryanodine receptor; kidney-type ryanodine receptor; Ryanodine receptor; ryanodine receptor 2; ryanodine receptor 2 (cardiac); ryanodine receptor 2, cardiac; ryanodine receptor type 2; ryanodine receptor type II; RyR; RYR2; RYR-2; Type 2 ryanodine receptor; VTSIP

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20191, 6262, 689560

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
B0LPN4, E9Q401, Q92736

Gene Symbols:
Ryr2

Immunogen:
A synthesized peptide derived from human RYR2(Accession Q92736), corresponding to amino acid residues M2782-T2832.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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Thermo Scientific

PIPA5104446

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Antigen:
Phospho-Glucocorticoid Receptor (Ser203)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Nr3c1

Gene Alias:
cytosolic/nuclear receptor; fb13f09; GCCR; Gcr; GCRST; glucocorticoid nuclear receptor variant 1; glucocorticoid receptor; glucocorticoid receptor 1; glucocorticoid receptor alpha; GR; gr alpha; GR Kit; Grl; Grl1; Grl-1; Nr3c1; Nuclear receptor subfamily 3 group C member 1; nuclear receptor subfamily 3, group C, member 1; nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor); OTTHUMP00000222854; OTTHUMP00000222858; utouto; utut; wu:fb13f09; zgc:113038

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14815, 2908

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P04150, P06537

Gene Symbols:
Nr3c1

Immunogen:
A synthesized peptide derived from human NR3C1(Accession P04150), corresponding to amino acid residues around phosphorylated Ser203.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA5104450

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Antigen:
CARD6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CARD6

Gene Alias:
Card6; CARD-containing inhibitor of Nod1 and Cardiak-induced NF-kB activation; caspase recruitment domain family member 6; caspase recruitment domain family, member 6; caspase recruitment domain protein 6; caspase recruitment domain-containing protein 6; CINCIN1; D730008L15

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
239319, 294770, 84674

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9BX69

Gene Symbols:
CARD6

Immunogen:
A synthesized peptide derived from human CARD6(Accession Q9BX69), corresponding to amino acid residues M1-L33.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5104451

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Antigen:
Factor VIII

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
F8

Gene Alias:
AHF; Antihemophilic factor; CF8; Cf-8; coagulation factor VIII; coagulation factor VIII A1 domain; coagulation factor VIII C2 domain; coagulation factor VIII, procoagulant component; coagulation factor VIII, procoagulant component (hemophilia A); coagulation factor VIIIc; DXS1253E; F8; F8B; F8C; Factor 8; Factor VIII; Factor VIII B chain; factor VIII F8B; factor VIII precursor; Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIIIa light chain; factor8; FVIII; HEMA; Procoagulant component; RP11-115M6.7

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14069, 2157

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P00451, Q06194

Gene Symbols:
F8

Immunogen:
A synthesized peptide derived from human F8(Accession P00451), corresponding to amino acid residues H2174-P2224.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG