PIPA5104476

BCKDK Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5104476-Each-of-1 In Stock ₹ 44,705.10

PIPA5104476 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

BCKDK

Classification

Polyclonal

Conjugate

Unconjugated

Gene

BCKDK

Gene Alias

[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial; AI327402; BCKDHKIN; BCKDK; BCKDKD; BCKD-kinase; BDK; branched chain alpha-ketoacid dehydrogenase kinase; branched chain ketoacid dehydrogenase kinase; branched-chain alpha-ketoacid dehydrogenase kinase; EC 2.7.11.4

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10295, 12041, 29603

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O14874, O55028, Q00972

Gene Symbols

BCKDK

Immunogen

A synthesized peptide derived from human BCKDK(Accession O14874), corresponding to amino acid residues L21-T71.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA5104538

--

Img

Thermo Scientific

PIPA5101420

--

Img

Thermo Scientific

PIPA5101411

--

Img

Thermo Scientific

PIPA5101493

--

Img

Thermo Scientific

PIPA5101417

--

Img

Thermo Scientific

PIPA5104289

--

Img

Thermo Scientific

PIPA5104372

--

Img

Thermo Scientific

PIPA5101491

--

Description

  • Antibody detects endogenous levels of total BCKD
  • The second major step in the catabolism of the branched-chain amino acids, isoleucine, leucine, and valine, is irreversibly catalyzed by the branched-chain alpha-keto acid dehydrogenase complex (BCKD), an inner-mitochondrial enzyme complex composed of 3 catalytic components: a branched-chain alpha-keto acid decarboxylase (E1), a dihydrolipoyl transacylase (E2), and a dihydrolipoamide dehydrogenase (E3)
  • The complex also contains 2 enzymes that regulated the state of activity of the BCKD complex: a kinase (BCKDK), and a phosphorylase
  • The ubiquitously expressed kinase contains 1 histidine kinase domain
  • Maple syrup urine disease (MSUD) is a pathology secondary to an enzyme defect in the catabolic pathway of leucine, isoleucine, and valine
  • Accumulation of these amino acids and their corresponding keto acids results in encephalopathy and progressive neurodegeneration in infants not treated for MSUD.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5104476

--


Antigen:
BCKDK

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BCKDK

Gene Alias:
[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial; AI327402; BCKDHKIN; BCKDK; BCKDKD; BCKD-kinase; BDK; branched chain alpha-ketoacid dehydrogenase kinase; branched chain ketoacid dehydrogenase kinase; branched-chain alpha-ketoacid dehydrogenase kinase; EC 2.7.11.4

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10295, 12041, 29603

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O14874, O55028, Q00972

Gene Symbols:
BCKDK

Immunogen:
A synthesized peptide derived from human BCKDK(Accession O14874), corresponding to amino acid residues L21-T71.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5104478

--


Antigen:
PDZD2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PDZD2

Gene Alias:
4930537L06Rik; A930022H17Rik; activated in prostate cancer protein; AIPC; Gm82; KIAA0300; mKIAA0300; PAPIN; PDZ domain containing 2; PDZ domain containing 3; PDZ domain-containing protein 2; PDZ domain-containing protein 3; PDZD2; PDZK3; Pin1; Plakophilin-related armadillo repeat protein-interacting PDZ protein; plakophilin-related armadillo repeat protein-interactive PDZ protein; Processed PDZ domain-containing protein 2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23037, 65034, 68070

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O15018, Q9QZR8

Gene Symbols:
PDZD2

Immunogen:
A synthesized peptide derived from human PDZD2(Accession O15018), corresponding to amino acid residues E67-G117.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5104479

--


Antigen:
LIGHT

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TNFSF14

Gene Alias:
CD258; Herpes virus entry mediator ligand; herpesvirus entry mediator ligand; HVEML; HVEM-L; Light; LTg; Ly113; sCD258; sLIGHT; soluble CD258; soluble LIGHT; Tnfsf14; TR2; tumor necrosis factor (ligand) superfamily, member 14; tumor necrosis factor ligand 1D; tumor necrosis factor ligand superfamily member 14; Tumor necrosis factor ligand superfamily member 14, membrane form; Tumor necrosis factor ligand superfamily member 14, soluble form; tumor necrosis factor superfamily member 14; UNQ391/PRO726

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
50930, 8740

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O43557, Q9QYH9

Gene Symbols:
TNFSF14

Immunogen:
A synthesized peptide derived from human TNFSF14(Accession O43557), corresponding to amino acid residues L61-P111.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5104480

--


Antigen:
Hairless

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HR

Gene Alias:
ALUNC; AU; ba; bldy; HAIR; hair growth associated; hairless; hairless homolog; Hairless protein; hr; HSA277165; HYPT4; Lysine-specific demethylase hairless; MUHH; MUHH1; N; protein hairless; rh; rh-bmh; rhino

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15460, 55806

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O43593, Q61645

Gene Symbols:
HR

Immunogen:
A synthesized peptide derived from human HR(Accession O43593), corresponding to amino acid residues V1014-R1064.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG