PIPA5104558
Phospho-RyR2 (Ser2814) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5104558-Each-of-1 | In Stock | ₹ 43,592.82 |
PIPA5104558 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,592.82
GST (18%): ₹ 7,846.708
Total Price: ₹ 51,439.528
Antigen
Phospho-RyR2 (Ser2814)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Ryr2
Gene Alias
9330127I20Rik; ARVC2; ARVD2; calcium release channel; cardiac muscle ryanodine receptor; Cardiac muscle ryanodine receptor-calcium release channel; cardiac ryanodine receptor 2; cardiac-type ryanodine receptor; hRYR-2; islet-type ryanodine receptor; kidney-type ryanodine receptor; Ryanodine receptor; ryanodine receptor 2; ryanodine receptor 2 (cardiac); ryanodine receptor 2, cardiac; ryanodine receptor type 2; ryanodine receptor type II; RyR; RYR2; RYR-2; Type 2 ryanodine receptor; VTSIP
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
403615, 6262
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q92736
Gene Symbols
Ryr2
Immunogen
A synthesized peptide derived from human RYR2(Accession Q92736), corresponding to amino acid residues around phosphorylated Ser2814.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Canine, Human
Product Type
Antibody
Isotype
IgG
Description
- Antibody detects endogenous levels of RYR2 only when phosphorylated at Ser2814
- Dihydropyridine receptor (DHPR) is a surface membrane protein critical for the excitation-contraction coupling of striated muscle
- DHPR and the sarcoplasmic reticulum ryanodine receptor (RyR) are two key components of the intracellular junctions, where depolarization of the surface membrane is converted into the release of Ca2+ from internal stores
- The alpha1-subunit of the DHPR contains a cytoplasmic loop which is thought to be involved in the interactions with RyR
- Phosphorylation of the DHPR alpha1-subunit is also thought to play a role in the functional interaction of DHPR and RyR
- Mutation in DHPR alpha1 results in excitation-contraction uncoupling, leading to muscular dysgenesis, a complete inactivity in developing skeletal muscles
- Cells that do not express RyR also lack excitation-contraction coupling and exhibit a severalfold reduction in Ca2+ current density.
Compare Similar Items
Show Difference
Antigen: Phospho-RyR2 (Ser2814)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Ryr2
Gene Alias: 9330127I20Rik; ARVC2; ARVD2; calcium release channel; cardiac muscle ryanodine receptor; Cardiac muscle ryanodine receptor-calcium release channel; cardiac ryanodine receptor 2; cardiac-type ryanodine receptor; hRYR-2; islet-type ryanodine receptor; kidney-type ryanodine receptor; Ryanodine receptor; ryanodine receptor 2; ryanodine receptor 2 (cardiac); ryanodine receptor 2, cardiac; ryanodine receptor type 2; ryanodine receptor type II; RyR; RYR2; RYR-2; Type 2 ryanodine receptor; VTSIP
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 403615, 6262
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q92736
Gene Symbols: Ryr2
Immunogen: A synthesized peptide derived from human RYR2(Accession Q92736), corresponding to amino acid residues around phosphorylated Ser2814.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Canine, Human
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-RyR2 (Ser2814)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Ryr2
Gene Alias:
9330127I20Rik; ARVC2; ARVD2; calcium release channel; cardiac muscle ryanodine receptor; Cardiac muscle ryanodine receptor-calcium release channel; cardiac ryanodine receptor 2; cardiac-type ryanodine receptor; hRYR-2; islet-type ryanodine receptor; kidney-type ryanodine receptor; Ryanodine receptor; ryanodine receptor 2; ryanodine receptor 2 (cardiac); ryanodine receptor 2, cardiac; ryanodine receptor type 2; ryanodine receptor type II; RyR; RYR2; RYR-2; Type 2 ryanodine receptor; VTSIP
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
403615, 6262
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q92736
Gene Symbols:
Ryr2
Immunogen:
A synthesized peptide derived from human RYR2(Accession Q92736), corresponding to amino acid residues around phosphorylated Ser2814.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Canine, Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-GRK2 (Ser29)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: GRK2
Gene Alias: ADRBK1; Adrbk-1; adrenergic beta receptor kinase 1; adrenergic receptor kinase, beta 1; adrenergic, beta, receptor kinase 1; BARK; BARK1; Bark-1; beta ARK; Beta-adrenergic receptor kinase 1; beta-adrenergic receptor kinase 1 beta ARK1; beta-AR kinase-1; betaARK1; BETA-ARK1; beta-ARK-1; EC 2.7.1.126; G protein-coupled receptor kinase 2; G-protein coupled receptor kinase 2; G-protein-coupled receptor kinase 2; grk 2; Grk2; GRK-2
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 110355, 156, 25238
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P25098, P26817, Q99MK8
Gene Symbols: GRK2
Immunogen: A synthesized peptide derived from human GRK2(Accession P25098), corresponding to amino acid residues around phosphorylated Ser29.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-GRK2 (Ser29)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
GRK2
Gene Alias:
ADRBK1; Adrbk-1; adrenergic beta receptor kinase 1; adrenergic receptor kinase, beta 1; adrenergic, beta, receptor kinase 1; BARK; BARK1; Bark-1; beta ARK; Beta-adrenergic receptor kinase 1; beta-adrenergic receptor kinase 1 beta ARK1; beta-AR kinase-1; betaARK1; BETA-ARK1; beta-ARK-1; EC 2.7.1.126; G protein-coupled receptor kinase 2; G-protein coupled receptor kinase 2; G-protein-coupled receptor kinase 2; grk 2; Grk2; GRK-2
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
110355, 156, 25238
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P25098, P26817, Q99MK8
Gene Symbols:
GRK2
Immunogen:
A synthesized peptide derived from human GRK2(Accession P25098), corresponding to amino acid residues around phosphorylated Ser29.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-ALK (Tyr1604)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ALK
Gene Alias: Alk; ALK tyrosine kinase receptor; ALK/NPM1 fusion gene; anaplastic lymphoma kinase; Anaplastic lymphoma kinase Ki1; Anaplastic Lymphoma Kinase p80; anaplastic lymphoma receptor tyrosine kinase; CD246; CD246 antigen; EC 2.7.10.1; kinase ALK; mutant anaplastic lymphoma kinase; NBLST3; npm-alk; p80; Tcrz; TFG/ALK
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11682, 238, 266802
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P97793, Q9UM73
Gene Symbols: ALK
Immunogen: A synthesized peptide derived from human ALK(Accession Q9UM73), corresponding to amino acid residues around phosphorylated Tyr1604.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-ALK (Tyr1604)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ALK
Gene Alias:
Alk; ALK tyrosine kinase receptor; ALK/NPM1 fusion gene; anaplastic lymphoma kinase; Anaplastic lymphoma kinase Ki1; Anaplastic Lymphoma Kinase p80; anaplastic lymphoma receptor tyrosine kinase; CD246; CD246 antigen; EC 2.7.10.1; kinase ALK; mutant anaplastic lymphoma kinase; NBLST3; npm-alk; p80; Tcrz; TFG/ALK
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11682, 238, 266802
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P97793, Q9UM73
Gene Symbols:
ALK
Immunogen:
A synthesized peptide derived from human ALK(Accession Q9UM73), corresponding to amino acid residues around phosphorylated Tyr1604.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-PKD2 (Ser812)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PKD2
Gene Alias: A MGC138466; APKD2; Autosomal dominant polycystic kidney disease type II protein; C030034P18Rik; MGC138468; PC2; Pc-2; PKD2; PKD4; polycystic kidney disease 2; polycystic kidney disease 2 (autosomal dominant); polycystic kidney disease 2 homolog; Polycystic kidney disease 2 protein; Polycystic kidney disease 2 protein homolog; polycystin 2; polycystin 2, transient receptor potential cation channel; polycystin-2; Polycystwin; R48321; RGD1559992; transient receptor potential cation channel subfamily P member 2; transient receptor potential cation channel, subfamily P, member 2; TRPP1; TRPP2
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18764, 498328, 5311
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: O35245, Q13563
Gene Symbols: PKD2
Immunogen: A synthesized peptide derived from human PKD2(Accession Q13563), corresponding to amino acid residues around phosphorylated Ser812.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-PKD2 (Ser812)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PKD2
Gene Alias:
A MGC138466; APKD2; Autosomal dominant polycystic kidney disease type II protein; C030034P18Rik; MGC138468; PC2; Pc-2; PKD2; PKD4; polycystic kidney disease 2; polycystic kidney disease 2 (autosomal dominant); polycystic kidney disease 2 homolog; Polycystic kidney disease 2 protein; Polycystic kidney disease 2 protein homolog; polycystin 2; polycystin 2, transient receptor potential cation channel; polycystin-2; Polycystwin; R48321; RGD1559992; transient receptor potential cation channel subfamily P member 2; transient receptor potential cation channel, subfamily P, member 2; TRPP1; TRPP2
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18764, 498328, 5311
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
O35245, Q13563
Gene Symbols:
PKD2
Immunogen:
A synthesized peptide derived from human PKD2(Accession Q13563), corresponding to amino acid residues around phosphorylated Ser812.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG