PIPA5104574

Phospho-BAP1 (Ser592) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5104574-Each-of-1 In Stock ₹ 44,705.10

PIPA5104574 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-BAP1 (Ser592)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

BAP1

Gene Alias

2300006C11Rik; AA989761; AW553466; BAP1; Brca1 associated protein 1; BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase); BRCA1-associated protein 1; Cerebral protein 6; cerebral protein-13; DKFZp686N04275; FLJ35406; FLJ37180; HUCEP-13; hucep-6; KIAA0272; mKIAA0272; Ubiquitin carboxyl-terminal hydrolase BAP1; ubiquitin C-terminal hydrolase X4; UCHL2; uch-x4

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

104416, 8314

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q92560, Q99PU7

Gene Symbols

BAP1

Immunogen

A synthesized peptide derived from human BAP1(Accession Q92560), corresponding to amino acid residues around phosphorylated Ser592.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of BAP1 only when phosphorylated at Ser592
  • BRCA1-associated protein-1, or BAP1, interacts with the RING finger domain of BRCA1
  • The N-terminal 240 amino acids of the predicted 729-amino acid human protein show homology to ubiquitin C-terminal hydrolases (UCHs), thiol proteases that catalyze proteolytic processing of ubiquitin
  • In addition, BAP1 contains an acidic region, a highly charged C-terminal region, and 2 putative nuclear localization signals
  • BAP1 and BRCA1 associate in vivo and have overlapping subnuclear localization patterns
  • BAP1 enhances BRCA1-mediated inhibition of breast cancer cell growth
  • Northern blot analysis indicates that BAP1 is expressed as a 4-kb mRNA in all human tissues tested, with A 4
  • 8-kb transcript expressed exclusively in testis
  • Northern blot analysis and in situ hybridization reveal that BAP1 and BRCA1 are coexpressed during murine breast development and remodeling
  • The BAP1 gene has been mapped to 3p21
  • 3, a region of loss of heterozygosity for breast cancer as well as frequently deleted in lung carcinomas
  • Intragenic homozygous rearrangements and deletions of BAP1 appear in lung carcinoma cell lines
  • It has been postulated that BAP1 is a tumor suppressor gene that functions in the BRCA1 growth control pathway.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5104574

--


Antigen:
Phospho-BAP1 (Ser592)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BAP1

Gene Alias:
2300006C11Rik; AA989761; AW553466; BAP1; Brca1 associated protein 1; BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase); BRCA1-associated protein 1; Cerebral protein 6; cerebral protein-13; DKFZp686N04275; FLJ35406; FLJ37180; HUCEP-13; hucep-6; KIAA0272; mKIAA0272; Ubiquitin carboxyl-terminal hydrolase BAP1; ubiquitin C-terminal hydrolase X4; UCHL2; uch-x4

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
104416, 8314

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q92560, Q99PU7

Gene Symbols:
BAP1

Immunogen:
A synthesized peptide derived from human BAP1(Accession Q92560), corresponding to amino acid residues around phosphorylated Ser592.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5104575

--


Antigen:
Phospho-BCL9L (Ser915)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BCL9L

Gene Alias:
B cell CLL/lymphoma 9-like; B9L; BC003321; B-cell CLL/lymphoma 9-like; B-cell CLL/lymphoma 9-like protein; B-cell lymphoma 9-like protein; BCL9-2; BCL9L; BCL9-like protein; BCL9-related beta-catenin-binding protein; DLNB11; nuclear co-factor of beta-catenin signalling; protein BCL9-2

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
283149, 300673, 80288

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q67FY2, Q86UU0

Gene Symbols:
BCL9L

Immunogen:
A synthesized peptide derived from human BCL9L(Accession Q86UU0), corresponding to amino acid residues around phosphorylated Ser915.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5104576

--


Antigen:
Phospho-Beclin 1 (Ser15)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BECN1

Gene Alias:
4921513J16Rik; 5430417M23Rik; APG6; Atg6; ATG6 autophagy related 6 homolog; Bcl-2-interacting protein beclin; beclin 1; beclin 1 (coiled-coil, moesin-like BCL2-interacting protein); beclin 1 (coiled-coil, myosin-like BCL2 interacting protein); beclin 1 (coiled-coil, myosin-like BCL2-interacting protein); beclin 1, autophagy related; beclin1; beclin-1; Beclin-1; beclin-1; Beclin-1-C 35 kDa; Beclin-1-C 37 kDa; becn1; Coiled-coil myosin-like BCL2-interacting protein; coiled-coil, myosin-like BCL2-interacting protein; GT197; hypothetical protein MGC73097; myosin-like BCL2 interacting protein; Protein GT197; testis secretory sperm-binding protein Li 215e; VPS30; zgc:73097

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
114558, 56208, 8678

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O88597, Q14457, Q91XJ1

Gene Symbols:
BECN1

Immunogen:
A synthesized peptide derived from human BECN1(Accession Q14457), corresponding to amino acid residues around phosphorylated Ser15.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5104577

--


Antigen:
Phospho-Bim (Ser69)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BCL2L11

Gene Alias:
1500006F24Rik; BAM; Bcl2 interacting mediator of cell death; bcl-2 interacting mediator of cell death; bcl-2 interacting protein Bim; BCL2 like 11; Bcl-2 like 11; Bcl-2 related apoptotic gene product BimL; bcl2-interacting mediator of cell death; BCL2L11; Bcl2-L-11; BCL2-like 11 (apoptosis facilitator); bcl-2-like protein 11; bcl-2-like protein 11-like; bcl-2-related ovarian death agonist; bcl-2-related ovarian death protein; BIM; Bim EL; Bim-A; BIM-alpha6; BIM-beta6; BIM-beta7; BIMEL; BimEL protein; BimL; BOD; OTTHUMP00000197013; OTTHUMP00000204247; Unknown (protein for MGC:134444)

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10018, 12125, 64547

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O43521, O54918, O88498

Gene Symbols:
BCL2L11

Immunogen:
A synthesized peptide derived from human BCL2L11(Accession O43521), corresponding to amino acid residues around phosphorylated Ser69.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG