PIPA5104607

Phospho-KSR1 (Ser392) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5104607-Each-of-1 In Stock ₹ 39,999.30

PIPA5104607 - Each of 1

₹ 39,999.30

In Stock

Quantity

1

Base Price: ₹ 39,999.30

GST (18%): ₹ 7,199.874

Total Price: ₹ 47,199.174

Antigen

Phospho-KSR1 (Ser392)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

KSR1

Gene Alias

AW492498; B-KSR1; CAP kinase; D11Bhm183e; D11Bhm184e; hb; HB protein; kinase KSR1; Kinase suppressor of Ras 1; Ksr; KSR1; mKSR1; OTTHUMP00000162931; protein Hb; RSU2

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16706, 8844

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q61097, Q8IVT5

Gene Symbols

KSR1

Immunogen

A synthesized peptide derived from mouse KSR1(Accession Q61097), corresponding to amino acid residues around phosphorylated Ser392.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Description

  • Antibody detects endogenous levels of KSR1 only when phosphorylated at Ser460, which site historically referenced as Ser392
  • Part of a multiprotein signaling complex which promotes phosphorylation of Raf family members and activation of downstream MAP kinases
  • Independently of its kinase activity, acts as MAP2K1/MEK1 and MAP2K2/MEK2-dependent allosteric activator of BRAF; upon binding to MAP2K1/MEK1 or MAP2K2/MEK2, dimerizes with BRAF and promotes BRAF-mediated phosphorylation of MAP2K1/MEK1 and/or MAP2K2/MEK2 (PubMed:29433126)
  • Promotes activation of MAPK1 and/or MAPK3, both in response to EGF and to cAMP
  • Its kinase activity is unsure
  • Some protein kinase activity has been detected in vitro, however the physiological relevance of this activity is unknown
  • [UniProt]

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Img

Thermo Scientific

PIPA5104607

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Antigen:
Phospho-KSR1 (Ser392)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KSR1

Gene Alias:
AW492498; B-KSR1; CAP kinase; D11Bhm183e; D11Bhm184e; hb; HB protein; kinase KSR1; Kinase suppressor of Ras 1; Ksr; KSR1; mKSR1; OTTHUMP00000162931; protein Hb; RSU2

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16706, 8844

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q61097, Q8IVT5

Gene Symbols:
KSR1

Immunogen:
A synthesized peptide derived from mouse KSR1(Accession Q61097), corresponding to amino acid residues around phosphorylated Ser392.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5104608

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Antigen:
Phospho-LAT (Tyr200)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LAT

Gene Alias:
36 kDa phospho-tyrosine adapter protein; 36 kDa phospho-tyrosine adaptor protein; Lat; LAT1; linker for activation of T cells; linker for activation of T cells, transmembrane adaptor; linker for activation of T-cells; linker for activation of T-cells family member 1; linker protein; p36-38; pp36

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16797, 27040

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O43561, O54957

Gene Symbols:
LAT

Immunogen:
A synthesized peptide derived from human LAT(Accession O43561), corresponding to amino acid residues around phosphorylated Tyr200.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5104609

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Antigen:
Phospho-L-Plastin (Tyr28)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LCP1

Gene Alias:
65 kDa macrophage protein; AW536232; bA139H14.1 (lymphocyte cytosolic protein 1 (L-plastin)); cb245; CP64; D14Ertd310e; DKFZp781A23186; epididymis secretory protein Li 37; fj24b12; FLJ25423; FLJ26114; FLJ39956; HEL-S-37; LC64P; LCP1; LCP-1; leucocyte-specific plastin 1; L-fimbrin; LPL; L-plastin; L-plastin (Lymphocyte cytosolic protein 1) (LCP-1) (65 kDa macrophage protein) (PP65); L-plastin (Lymphocyte cytosolic protein 1) (LCP-1) (LC64P); lymphocyte cytosolic plastin 1; lymphocyte cytosolic protein 1; lymphocyte cytosolic protein 1 (L-plastin); Lymphocyte cytosolic protein-1 (plasmin); plastin 2; plastin 2, L; plastin-2; Pls2; pp65; wu:fj24b12

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18826, 3936

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P13796, Q61233

Gene Symbols:
LCP1

Immunogen:
A synthesized peptide derived from human LCP1(Accession P13796), corresponding to amino acid residues around phosphorylated Tyr28.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5104611

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Antigen:
Phospho-MCM3 (Ser112)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MCM3

Gene Alias:
AL033361; C80350; cervical cancer proto-oncogene 5; DNA polymerase alpha holoenzyme-associated protein P1; DNA replication factor MCM3; DNA replication licensing factor MCM3; HCC5; hRlf beta subunit; MCM3; MCM3 minichromosome maintenance deficient 3; Mcmd; Mcmd3; MGC1157; mini chromosome maintenance deficient; minichromosome maintenance complex component 3; minichromosome maintenance deficient 3; minichromosome maintenance deficient 3 (S. cerevisiae); P1; P1.h; p1.m; p102; P1-MCM3; replication licensing factor, beta subunit; RLF subunit beta; RLFB; RP1-108C2.3

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17215, 316273, 4172

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P25205, P25206

Gene Symbols:
MCM3

Immunogen:
A synthesized peptide derived from human MCM3(Accession P25205), corresponding to amino acid residues around phosphorylated Ser112.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG