PIPA5104628

Phospho-PAK1/PAK2 (Ser199, Ser204, Ser192, Ser197) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5104628-Each-of-1 In Stock ₹ 39,999.30

PIPA5104628 - Each of 1

₹ 39,999.30

In Stock

Quantity

1

Base Price: ₹ 39,999.30

GST (18%): ₹ 7,199.874

Total Price: ₹ 47,199.174

Antigen

Phospho-PAK1/PAK2 (Ser199, Ser204, Ser192, Ser197)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Pak1

Gene Alias

5330420P17Rik; A130002K10Rik; activated protein kinase alpha; AI836325; Alpha-PAK; AW045634; Beta-PAK; CDC42/RAC effector kinase PAK-A; C-t-PAK2; D16Ertd269e; gamma pak; gamma-PAK; mKIAA4182; Oligophrenin-3; OPHN3; p21 (CDKN1A)-activated kinase 1; p21 (CDKN1A)-activated kinase 2; p21 (RAC1) activated kinase 1; p21 (RAC1) activated kinase 2; p21 protein (Cdc42/Rac)-activated kinase 1; p21 protein (Cdc42/Rac)-activated kinase 2; p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast); p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related); p21-activated kinase 1; p21-activated kinase 2; p27; p34; p58; p65-PAK; p68-PAK; PAK alpha; PAK beta; PAK gamma; PAK1; PAK-1; Pak2; PAK-2; PAK-2p27; PAK-2p34; PAK3; PAK-3; PAK65; Paka; PAKalpha; PAKgamma; Protein kinase MUK2; S6/H4 kinase; Serine/threonine-protein kinase PAK 1; serine/threonine-protein kinase PAK 2; STE20 homolog, yeast

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

18479, 224105, 29431, 29432, 5058, 5062

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O88643, P35465, Q13153, Q13177, Q64303, Q8CIN4

Gene Symbols

Pak1, PAK2

Immunogen

A synthesized peptide derived from human PAK1(Accession Q13153), corresponding to amino acid residues around phosphorylated Ser204.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • Antibody detectsAntibody detects endogenous levels of PAK1 when phosphorylated at Ser199/204 or PAK2 when phosphorylated at Ser192/197
  • Three isoforms of serine/threonine kinases, designated alphaPAK p68, betaPAK p65 and gammaPAK p62, have been shown to exhibit a high degree of sequence homology with the S
  • cerevisiae kinase Ste 20, involved in pheromone signaling
  • The alpha, beta and gammaPAK isoforms complex specifically with Rac1 and Cdc42 in their active GTP-bound state, inhibiting their intrinsic GTPase activity leading to their autophosphorylation
  • There are eight sites of autophosphorylation on gammaPAK, including Ser 19, Ser 141 and Thr 402, and phosphorylation of Ser 141 and Thr 402 is correlated with gammaPAK activation
  • Once phosphorylated and their affinity for Rac/Cdc42 reduced, the PAK isoforms disassociate from the complex to seek downstream substrates.

Compare Similar Items

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Img

Thermo Scientific

PIPA5104628

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Antigen:
Phospho-PAK1/PAK2 (Ser199, Ser204, Ser192, Ser197)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Pak1

Gene Alias:
5330420P17Rik; A130002K10Rik; activated protein kinase alpha; AI836325; Alpha-PAK; AW045634; Beta-PAK; CDC42/RAC effector kinase PAK-A; C-t-PAK2; D16Ertd269e; gamma pak; gamma-PAK; mKIAA4182; Oligophrenin-3; OPHN3; p21 (CDKN1A)-activated kinase 1; p21 (CDKN1A)-activated kinase 2; p21 (RAC1) activated kinase 1; p21 (RAC1) activated kinase 2; p21 protein (Cdc42/Rac)-activated kinase 1; p21 protein (Cdc42/Rac)-activated kinase 2; p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast); p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related); p21-activated kinase 1; p21-activated kinase 2; p27; p34; p58; p65-PAK; p68-PAK; PAK alpha; PAK beta; PAK gamma; PAK1; PAK-1; Pak2; PAK-2; PAK-2p27; PAK-2p34; PAK3; PAK-3; PAK65; Paka; PAKalpha; PAKgamma; Protein kinase MUK2; S6/H4 kinase; Serine/threonine-protein kinase PAK 1; serine/threonine-protein kinase PAK 2; STE20 homolog, yeast

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18479, 224105, 29431, 29432, 5058, 5062

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O88643, P35465, Q13153, Q13177, Q64303, Q8CIN4

Gene Symbols:
Pak1, PAK2

Immunogen:
A synthesized peptide derived from human PAK1(Accession Q13153), corresponding to amino acid residues around phosphorylated Ser204.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5104629

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Antigen:
Phospho-PAK2 (Ser20)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Pak2

Gene Alias:
5330420P17Rik; A130002K10Rik; AI836325; Alpha-PAK; Beta-PAK; C-t-PAK2; D16Ertd269e; gamma pak; gamma-PAK; mKIAA4182; Oligophrenin-3; OPHN3; p21 (CDKN1A)-activated kinase 2; p21 (RAC1) activated kinase 2; p21 protein (Cdc42/Rac)-activated kinase 2; p21-activated kinase 2; p27; p34; p58; p65-PAK; PAK alpha; PAK beta; PAK gamma; PAK1; PAK-1; Pak2; PAK-2; PAK-2p27; PAK-2p34; PAK3; PAK-3; PAK65; PAKgamma; S6/H4 kinase; serine/threonine-protein kinase PAK 2

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
224105, 29432, 5062

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q13177, Q64303, Q8CIN4

Gene Symbols:
Pak2

Immunogen:
A synthesized peptide derived from human PAK2(Accession Q13177), corresponding to amino acid residues around phosphorylated Ser20.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5104630

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Antigen:
Phospho-PBK (Thr9)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PBK

Gene Alias:
2810434B10Rik; AW538537; Cancer/testis antigen 84; CT84; D14Ertd732e; epididymis luminal protein 164; HEL164; Lymphokine-activated killer T-cell-originated protein kinase; MAPKK-like protein kinase; Nori-3; PBK; PDZ binding kinase; PDZ-binding kinase; serine/threonine protein kinase; spermatogenesis-related protein kinase; SPK; T-LAK cell-originated protein kinase; TOPK

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
52033, 55872

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q96KB5, Q9JJ78

Gene Symbols:
PBK

Immunogen:
A synthesized peptide derived from human PBK(Accession Q96KB5), corresponding to amino acid residues around phosphorylated Thr9.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5104631

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Antigen:
Phospho-PLCB3 (Ser1105)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Plcb3

Gene Alias:
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3; EC 3.1.4.11; mKIAA4098; Phosphoinositide phospholipase C-beta-3; phosphoinositide-specific phospholipase c; phospholipase C beta 3; phospholipase C, beta 3; phospholipase C, beta 3 (phosphatidylinositol-specific); phospholipase C-beta-3; PLC beta 3; Plcb3; PLCbeta3; PLC-beta3; PLC-beta-3

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18797, 29322, 5331

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P51432, Q01970, Q99JE6

Gene Symbols:
Plcb3

Immunogen:
A synthesized peptide derived from human PLCB3(Accession Q01970), corresponding to amino acid residues around phosphorylated Ser1105.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG