PIPA5104639

Phospho-PTPRA (Tyr798) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5104639-Each-of-1 In Stock ₹ 39,999.30

PIPA5104639 - Each of 1

₹ 39,999.30

In Stock

Quantity

1

Base Price: ₹ 39,999.30

GST (18%): ₹ 7,199.874

Total Price: ₹ 47,199.174

Antigen

Phospho-PTPRA (Tyr798)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Ptpra

Gene Alias

HEPTP; HLPR; Hptp alpha; HPTPA; HPTPalpha; LCA-related phosphatase; Leukocyte common antigen-related peptide (protein tyrosine phosphate); Lrp; protein tyrosine phosphatase alpha; protein tyrosine phosphatase, receptor type A; protein tyrosine phosphatase, receptor type, A; protein tyrosine phosphatase, receptor type, alpha polypeptide; protein-tyrosine phosphatase alpha; PTP alpha; Ptpa; Ptpalpha; PTPase-alpha; PTPLCA-related phosphatase; PTPRA; PTPRL2; PTPTY-28; Receptor-type tyrosine-protein phosphatase alpha; RPTP alpha; RPTPA; Rptpalpha; R-PTP-alpha; Rptra; Rptralpha; tyrosine phosphatase alpha

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

19262, 25167, 5786

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P18052, P18433, Q03348

Gene Symbols

Ptpra

Immunogen

A synthesized peptide derived from human PTPRA(Accession P18433), corresponding to amino acid residues around phosphorylated Tyr798.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG

Description

  • Antibody detects endogenous levels of PTP alpha only when phosphorylated at Tyr798
  • Phosphorylation of receptors by protein kinases is a process that can be reversed by a group of enzymes called protein phosphatases
  • Coordinated control of kinases and phosphatases provides the cell with the capacity to rapidly switch between phosphorylated and dephosphorylated protein states in dynamic response to environmental stimuli
  • Activation of critical enzymes by kinase phosphorylation alone is not enough to provide adequate regulation - it is the combination with phosphatase dephosphorylation that effectively creates on/off switches to control cellular events
  • Errors in control, either through kinases or their counterpart phosphatases, can lead to unchecked cell growth attributable to human cancers and developmental disorders
  • Potential mechanisms to control dephosphorylation include changes in the expression of protein phosphatases, their subcellular localization, phosphorylation of phosphatase catalytic and regulatory subunits and regulation by endogenous phosphatase inhibitors
  • Most protein phosphatases are not stringently specific for their substrates
  • Consequently, changes in phosphatase activity may have a broad impact on dephosphorylation and turnover of phosphoproteins that are substrates for different kinases
  • This may be an important point of control to connect cellular circuitry of interrelated signaling pathways, and to synchronize physiological responses.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5104639

--


Antigen:
Phospho-PTPRA (Tyr798)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ptpra

Gene Alias:
HEPTP; HLPR; Hptp alpha; HPTPA; HPTPalpha; LCA-related phosphatase; Leukocyte common antigen-related peptide (protein tyrosine phosphate); Lrp; protein tyrosine phosphatase alpha; protein tyrosine phosphatase, receptor type A; protein tyrosine phosphatase, receptor type, A; protein tyrosine phosphatase, receptor type, alpha polypeptide; protein-tyrosine phosphatase alpha; PTP alpha; Ptpa; Ptpalpha; PTPase-alpha; PTPLCA-related phosphatase; PTPRA; PTPRL2; PTPTY-28; Receptor-type tyrosine-protein phosphatase alpha; RPTP alpha; RPTPA; Rptpalpha; R-PTP-alpha; Rptra; Rptralpha; tyrosine phosphatase alpha

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19262, 25167, 5786

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P18052, P18433, Q03348

Gene Symbols:
Ptpra

Immunogen:
A synthesized peptide derived from human PTPRA(Accession P18433), corresponding to amino acid residues around phosphorylated Tyr798.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5104640

--


Antigen:
Phospho-RAC1 (Ser71)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Rac1

Gene Alias:
AL023026; cell migration-inducing gene 5 protein; D5Ertd559e; GTPase; MGC111543; MIG5; p21-Rac1; Rac 1b; Rac family small GTPase 1; RAC1; Rac-1; Rac2; rac2 GTP-binding protein; ras-like protein TC25; RAS-related C3 botulinum substrate 1; ras-related C3 botulinum toxin substrate 1; ras-related C3 botulinum toxin substrate 1 (rho family small GTP binding protein Rac1); ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1); rho family, small GTP binding protein Rac1; TC25; TC-25

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19353, 363875, 5879

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P63000, P63001, Q6RUV5

Gene Symbols:
Rac1

Immunogen:
A synthesized peptide derived from human RAC1(Accession P63000), corresponding to amino acid residues around phosphorylated Ser71.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5104643

--


Antigen:
Phospho-REPS1 (Ser709)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
REPS1

Gene Alias:
BB161292; MIG2; RALBP1; RalBP1 associated Eps domain containing 1; RalBP1 associated Eps domain containing protein; ralBP1-associated Eps domain-containing protein 1; RalBP1-interacting protein 1; Reps1

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19707, 85021

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O54916, Q96D71

Gene Symbols:
REPS1

Immunogen:
A synthesized peptide derived from human REPS1(Accession Q96D71), corresponding to amino acid residues around phosphorylated Ser709.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5104644

--


Antigen:
Phospho-RICTOR (Thr1135)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Rictor

Gene Alias:
4921505C17Rik; 6030405M08Rik; AVO3; AVO3 homolog; AW492497; D530039E11Rik; DKFZp686B11164; Fyb; FYN binding protein; hAVO3; Kiaa1999; mAVO3; MGC39830; PIA; pianissimo; protein pianissimo; Rapamycin-insensitive companion of mTOR; rictor; RPTOR independent companion of MTOR complex 2; RPTOR independent companion of MTOR, complex 2; TORC2-specific protein AVO3

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
253260, 78757

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q6QI06, Q6R327

Gene Symbols:
Rictor

Immunogen:
A synthesized peptide derived from human RICTOR(Accession Q6R327), corresponding to amino acid residues around phosphorylated Thr1135.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG