PIPA5104654

Phospho-SKP2 (Ser64) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5104654-Each-of-1 In Stock ₹ 43,592.82

PIPA5104654 - Each of 1

₹ 43,592.82

In Stock

Quantity

1

Base Price: ₹ 43,592.82

GST (18%): ₹ 7,846.708

Total Price: ₹ 51,439.528

Antigen

Phospho-SKP2 (Ser64)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SKP2

Gene Alias

4930500A04Rik; CDK2/cyclin A-associated protein p45; cyclin A/CDK2-associated protein p45; Cyclin-A/CDK2-associated protein p45; FBL1; F-box protein Skp2; F-box/LRR-repeat protein 1; F-box/WD-40 protein 1; FBXL1; FLB1; FWD1; MGC1366; OTTHUMP00000221389; p45; p45skp2; RGD1562456; Skp2; S-phase kinase-associated protein 2; S-phase kinase-associated protein 2 (p45); S-phase kinase-associated protein 2, E3 ubiquitin protein ligase

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

27401, 294790, 6502

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q13309, Q9Z0Z3

Gene Symbols

SKP2

Immunogen

A synthesized peptide derived from human SKP2(Accession Q13309), corresponding to amino acid residues around phosphorylated Ser64.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of SKP2/p45 only when phosphorylated at Ser64
  • Skp2 (S-phase Kinase-associated Protein 2) belongs to the family of F-box proteins that interact with the Cyclin A-Cdk2 complex
  • Skp2 is essential for the G1-S transition in both transformed cells and diploid fibroblasts
  • Biochemical and genetic experiments have demonstrated that Skp2 is required for the ubiquitination and consequent degradation of p27 in cultured mammalian cells and in vitro reconstitution assays
  • In normal tissues, Skp2 is expressed in tonsil and placenta
  • In tumor tissues, Skp2 is expressed widely, in some colon, prostate, pancreas, and skin cancers, with high expression in lung, breast, ovarian, and endometrial cancers
  • Research suggests that Skp2 plays a role in oncogenesis, particularly in the pathogenesis of lymphomas and breast cancers.

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Img

Thermo Scientific

PIPA5104654

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Antigen:
Phospho-SKP2 (Ser64)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SKP2

Gene Alias:
4930500A04Rik; CDK2/cyclin A-associated protein p45; cyclin A/CDK2-associated protein p45; Cyclin-A/CDK2-associated protein p45; FBL1; F-box protein Skp2; F-box/LRR-repeat protein 1; F-box/WD-40 protein 1; FBXL1; FLB1; FWD1; MGC1366; OTTHUMP00000221389; p45; p45skp2; RGD1562456; Skp2; S-phase kinase-associated protein 2; S-phase kinase-associated protein 2 (p45); S-phase kinase-associated protein 2, E3 ubiquitin protein ligase

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
27401, 294790, 6502

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q13309, Q9Z0Z3

Gene Symbols:
SKP2

Immunogen:
A synthesized peptide derived from human SKP2(Accession Q13309), corresponding to amino acid residues around phosphorylated Ser64.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5104655

--


Antigen:
Phospho-SMAD1 (Ser206)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SMAD1

Gene Alias:
AI528653, BSP1, BSP-1, dwarfin-A, Dwf-A, DWFC, hSMAD1, JV41, JV4-1, JV5-1, MAD (mothers against decapentaplegic, Drosophila) homolog 1, MAD homolog 1, MAD homolog1 (mothers against decapentaplegic, Drosophila), MAD, mothers against decapentaplegic homolog 1, Madh1, MADH5, MADR1, Mad-related protein 1, Mlp1, mMad1, mothers against decapentaplegic homolog 1, mothers against DPP homolog 1, mothers-against-DPP-related 1, Mothers-against-DPP-related-1, MusMLP, OTTHUMP00000220456, SMAD, Smad 1, SMAD family member 1, SMAD, mothers against DPP homolog 1, Smad1, SMAD5, TGF-beta signaling protein 1, transforming growth factor-beta signaling protein 1, Transforming growth factor-beta-signaling protein 1

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17125, 25671, 4086

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P70340, P97588, Q15797

Gene Symbols:
SMAD1

Immunogen:
A synthesized peptide derived from human SMAD1(Accession Q15797), corresponding to amino acid residues around phosphorylated Ser206.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5104658

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Antigen:
Phospho-SRC3 (Thr24)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NCOA3

Gene Alias:
2010305B15Rik; Actr; AIB1; AIB-1; amplified in breast cancer 1 protein; amplified in breast cancer-1 protein homolog; AW321064; BHLHE42; CAGH16; CBP-interacting protein; class E basic helix-loop-helix protein 42; CTG26; KAT13B; MGC141848; NCOA3; NCoA-3; Nuclear receptor coactivator 3; OTTHUMP00000031716; p/Cip; pCip; Rac3; RAC-3; Receptor-associated coactivator 3; RP5-1049G16.3; Src3; SRC-3; steroid receptor coactivator protein 3; Thyroid hormone receptor activator molecule 1; TNRC14; TNRC16; Tram1; Tram-1

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17979, 8202, 84584

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O09000, Q9EPU2, Q9Y6Q9

Gene Symbols:
NCOA3

Immunogen:
A synthesized peptide derived from human NCOA3(Accession Q9Y6Q9), corresponding to amino acid residues around phosphorylated Thr24.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5104660

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Antigen:
Phospho-Survivin (Thr34)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Birc5

Gene Alias:
AAC-11; AP14; Api4; apoptosis inhibitor 4; Apoptosis inhibitor survivin; baculoviral IAP repeat containing 5; baculoviral IAP repeat-containing 5; baculoviral IAP repeat-containing 5 (survivin); baculoviral IAP repeat-containing protein 5; BIRC 5; BIRC5; EPR 1; EPR-1; Iap4; inhibitor of apoptosis; survivin; survivin variant 3 alpha; survivin40; SVV; TIAP

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11799, 332, 64041

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O15392, O70201, Q9JHY7

Gene Symbols:
Birc5

Immunogen:
A synthesized peptide derived from human BIRC5(Accession O15392), corresponding to amino acid residues around phosphorylated Thr34.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG