PIPA5104665
Phospho-Tau (Ser733) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5104665-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5104665 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
Phospho-Tau (Ser733)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MAPT
Gene Alias
AI413597; AW045860; DDPAC; FLJ31424; FTDP17; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; map tau; Mapt; MAPTL; MGC138549; microtubule associated protein tau; microtubule-associated protein tau; microtubule-associated protein tau, isoform 4; microtubules; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; neurofibrillary tangles; Neuronal Marker; paired helical filament-tau; PHFtau; PHF-tau; PPND; PPP1R103; protein phosphatase 1, regulatory subunit 103; pTau; RNPTAU; Tau; Tau microtubule-associated protein; tau protein; Tau-4; Tau5; Unknown (protein for MGC:134287)
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17762, 29477, 4137
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P10636, P10637, P19332
Gene Symbols
MAPT
Immunogen
A synthesized peptide derived from human MAPT(Accession P10636), corresponding to amino acid residues around phosphorylated Ser733.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Description
- Antibody detects endogenous levels of Tau only when phosphorylated at Ser733, which site historically referenced as Ser416
- Tau is a neuronal microtubule-associated protein found predominantly on axons
- The function of Tau is to promote tubulin polymerization and stabilize microtubules
- The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both
- Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome
- The short isoforms allow plasticity of the cytoskeleton while the longer isoforms may preferentially play a role in its stabilization
- In its hyper-phosphorylated form, Tau is the major component of paired helical filaments (PHF), the building block of neurofibrillary lesions in Alzheimer's diseases (AD) brain
- Hyper-phosphorylation impairs the microtubule binding function of Tau, resulting in the destabilization of microtubules in AD brains, μgtimately leading to the degeneration of the affected neurons
- Numerous serine/threonine kinases phosphorylate Tau, including GSK-3beta, protein kinase A (PKA), cyclin-dependent kinase 5 (cdk5) and casein kinase II
- Hyper-phosphorylated Tau is found in neurofibrillary lesions in a range and other central nervous system disorders such as Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
Compare Similar Items
Show Difference
Antigen: Phospho-Tau (Ser733)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MAPT
Gene Alias: AI413597; AW045860; DDPAC; FLJ31424; FTDP17; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; map tau; Mapt; MAPTL; MGC138549; microtubule associated protein tau; microtubule-associated protein tau; microtubule-associated protein tau, isoform 4; microtubules; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; neurofibrillary tangles; Neuronal Marker; paired helical filament-tau; PHFtau; PHF-tau; PPND; PPP1R103; protein phosphatase 1, regulatory subunit 103; pTau; RNPTAU; Tau; Tau microtubule-associated protein; tau protein; Tau-4; Tau5; Unknown (protein for MGC:134287)
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17762, 29477, 4137
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P10636, P10637, P19332
Gene Symbols: MAPT
Immunogen: A synthesized peptide derived from human MAPT(Accession P10636), corresponding to amino acid residues around phosphorylated Ser733.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-Tau (Ser733)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MAPT
Gene Alias:
AI413597; AW045860; DDPAC; FLJ31424; FTDP17; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; map tau; Mapt; MAPTL; MGC138549; microtubule associated protein tau; microtubule-associated protein tau; microtubule-associated protein tau, isoform 4; microtubules; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; neurofibrillary tangles; Neuronal Marker; paired helical filament-tau; PHFtau; PHF-tau; PPND; PPP1R103; protein phosphatase 1, regulatory subunit 103; pTau; RNPTAU; Tau; Tau microtubule-associated protein; tau protein; Tau-4; Tau5; Unknown (protein for MGC:134287)
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17762, 29477, 4137
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P10636, P10637, P19332
Gene Symbols:
MAPT
Immunogen:
A synthesized peptide derived from human MAPT(Accession P10636), corresponding to amino acid residues around phosphorylated Ser733.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-TBC1D1 (Ser237)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TBC1D1
Gene Alias: 1110062G02Rik; AI385682; AW555803; Kiaa1108; LYN; Lyncein; mKIAA1108; TBC; Tbc1; TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1; TBC1 domain family member 1; TBC1 domain family, member 1; Tbc1d1; tre-2/USP6, BUB2, cdc16) domain family, member 1
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23216, 360937, 57915
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q60949, Q86TI0
Gene Symbols: TBC1D1
Immunogen: A synthesized peptide derived from mouse TBC1D1 around the phosphorylation site of Ser237.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-TBC1D1 (Ser237)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TBC1D1
Gene Alias:
1110062G02Rik; AI385682; AW555803; Kiaa1108; LYN; Lyncein; mKIAA1108; TBC; Tbc1; TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1; TBC1 domain family member 1; TBC1 domain family, member 1; Tbc1d1; tre-2/USP6, BUB2, cdc16) domain family, member 1
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23216, 360937, 57915
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q60949, Q86TI0
Gene Symbols:
TBC1D1
Immunogen:
A synthesized peptide derived from mouse TBC1D1 around the phosphorylation site of Ser237.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-TBC1D1 (Thr590)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TBC1D1
Gene Alias: 1110062G02Rik; AI385682; AW555803; Kiaa1108; LYN; Lyncein; mKIAA1108; TBC; Tbc1; TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1; TBC1 domain family member 1; TBC1 domain family, member 1; Tbc1d1; tre-2/USP6, BUB2, cdc16) domain family, member 1
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23216, 360937, 57915
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q60949, Q86TI0
Gene Symbols: TBC1D1
Immunogen: A synthesized peptide derived from mouse TBC1D1 around the phosphorylation site of Thr590.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-TBC1D1 (Thr590)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TBC1D1
Gene Alias:
1110062G02Rik; AI385682; AW555803; Kiaa1108; LYN; Lyncein; mKIAA1108; TBC; Tbc1; TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1; TBC1 domain family member 1; TBC1 domain family, member 1; Tbc1d1; tre-2/USP6, BUB2, cdc16) domain family, member 1
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23216, 360937, 57915
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q60949, Q86TI0
Gene Symbols:
TBC1D1
Immunogen:
A synthesized peptide derived from mouse TBC1D1 around the phosphorylation site of Thr590.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-TNK1 (Tyr277)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TNK1
Gene Alias: CD38 negative kinase 1; Kinase of embryonic stem cells; Kos1; MGC46193; non-receptor tyrosine kinase; non-receptor tyrosine-protein kinase TNK1; TNK1; Tnk1a; Tnk1b; tyrosine kinase non receptor 1; tyrosine kinase, non-receptor 1; tyrosine kinase, non-receptor, 1
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 303247, 83813, 8711
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q13470, Q99ML2
Gene Symbols: TNK1
Immunogen: A synthesized peptide derived from human TNK1(Accession Q13470), corresponding to amino acid residues around phosphorylated Tyr277.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-TNK1 (Tyr277)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TNK1
Gene Alias:
CD38 negative kinase 1; Kinase of embryonic stem cells; Kos1; MGC46193; non-receptor tyrosine kinase; non-receptor tyrosine-protein kinase TNK1; TNK1; Tnk1a; Tnk1b; tyrosine kinase non receptor 1; tyrosine kinase, non-receptor 1; tyrosine kinase, non-receptor, 1
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
303247, 83813, 8711
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q13470, Q99ML2
Gene Symbols:
TNK1
Immunogen:
A synthesized peptide derived from human TNK1(Accession Q13470), corresponding to amino acid residues around phosphorylated Tyr277.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG