PIPA5104796

Phospho-Cyclin B1 (Ser147) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5104796-Each-of-1 In Stock ₹ 44,705.10

PIPA5104796 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-Cyclin B1 (Ser147)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Ccnb1

Gene Alias

Ccn-2; CCNB; Ccnb1; Ccnb1-rs1; Ccnb1-rs13; Cycb; Cycb1; Cycb1-rs1; Cycb-4; Cycb-5; cyclin B; cyclin B1; cyclin B1, related sequence 1; cyclin B1, related sequence 13; G2/mitotic-specific cyclin B1; G2/mitotic-specific cyclin-B1; I79_013589; OTTHUMP00000221981; OTTHUMP00000223023

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

25203, 268697, 891

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P14635, P24860, P30277

Gene Symbols

Ccnb1

Immunogen

A synthesized peptide derived from human CCNB1(Accession P14635), corresponding to amino acid residues around phosphorylated Ser147.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of Cyclin B1 only when phosphorylated at Serine 147
  • Cyclins bind to and regulate the activity of the Cyclin dependent protein kinases (CDKs)
  • Cyclin B1 or CCNB1 is a regulatory protein involved in mitosis
  • It is essential for the control of the cell cycle at the G2/M transition
  • Cyclin B1 complexes with p34 (cdc2) to form the maturation-promoting factor (MPF)
  • Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase
  • Cyclin B1 is not ubiquitinated during G2/M phase, resulting in its steady accumulation during G2 phase, followed by abrupt APC dependent destruction at the end of mitosis
  • Destruction of Cyclin B1 is required for cell cycle progression
  • Cyclin B1 is overexpressed in various cancers, including breast, prostate, and non-small cell lung cancer.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5104796

--


Antigen:
Phospho-Cyclin B1 (Ser147)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ccnb1

Gene Alias:
Ccn-2; CCNB; Ccnb1; Ccnb1-rs1; Ccnb1-rs13; Cycb; Cycb1; Cycb1-rs1; Cycb-4; Cycb-5; cyclin B; cyclin B1; cyclin B1, related sequence 1; cyclin B1, related sequence 13; G2/mitotic-specific cyclin B1; G2/mitotic-specific cyclin-B1; I79_013589; OTTHUMP00000221981; OTTHUMP00000223023

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
25203, 268697, 891

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P14635, P24860, P30277

Gene Symbols:
Ccnb1

Immunogen:
A synthesized peptide derived from human CCNB1(Accession P14635), corresponding to amino acid residues around phosphorylated Ser147.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5104797

--


Antigen:
Phospho-B-RAF (Ser446)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BRAF

Gene Alias:
94 kDa B-raf protein; 9930012E13Rik; AA120551; AA387315; AA473386; Braf; B-raf; B-raf protein; B-raf protein isoform 1; B-raf protein isoform 2; B-Raf proto-oncogene serine/threonine-protein kinase; B-Raf proto-oncogene serine/threonine-protein kinase (p94); B-Raf proto-oncogene, serine/threonine kinase; Braf transforming gene; BRAF1; B-RAF1; Braf2; Braf-2; C230098H17; C87398; C-RMIL; D6Ertd631e; FLJ95109; MGC126806; murine sarcoma viral (v-raf) oncogene homolog B1; NS7; p94; Proto-oncogene B-Raf; proto-oncogene c-Rmil; RAFB1; RMIL; rmil serine/threonine-protein kinase; serine/threonine kinase; serine/threonine-protein kinase B-raf; Serine/threonine-protein kinase Rmil; v-raf murine sarcoma viral oncogene homolog B; v-raf murine sarcoma viral oncogene homolog B1

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
109880, 673

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P15056, P28028

Gene Symbols:
BRAF

Immunogen:
A synthesized peptide derived from human BRAF(Accession P15056), corresponding to amino acid residues around phosphorylated Ser446.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA5104798

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Antigen:
Phospho-Ezrin (Thr567)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ezr

Gene Alias:
AW146364; CVIL; CVL; Cytovillin; cytovillin 2; DKFZp762H157; epididymis secretory protein Li 105; ezr; ezr.L; ezr.S; EZRI; Ezrin; ezrin L homeolog; ezrin L homeolog; ezrin S homeolog; FLJ26216; HEL-S-105; MGC1584; p81; R75297; VIL2; villin 2; villin 2 (ezrin); villin-2; XELAEV_18027043mg

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22350, 54319, 7430

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P15311, P26040, P31977

Gene Symbols:
Ezr

Immunogen:
A synthesized peptide derived from human EZR(Accession P15311), corresponding to amino acid residues around phosphorylated Thr567.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5104799

--


Antigen:
Phospho-Ezrin (Tyr354)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ezr

Gene Alias:
AW146364; CVIL; CVL; Cytovillin; cytovillin 2; DKFZp762H157; epididymis secretory protein Li 105; ezr; ezr.L; ezr.S; EZRI; Ezrin; ezrin L homeolog; ezrin L homeolog; ezrin S homeolog; FLJ26216; HEL-S-105; MGC1584; p81; R75297; VIL2; villin 2; villin 2 (ezrin); villin-2; XELAEV_18027043mg

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22350, 54319, 7430

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P15311, P26040, P31977

Gene Symbols:
Ezr

Immunogen:
A synthesized peptide derived from human EZR(Accession P15311), corresponding to amino acid residues around phosphorylated Tyr354.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG