PIPA5104891
Phospho-TPL2 (Thr290) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5104891-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5104891 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
Phospho-TPL2 (Thr290)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MAP3K8
Gene Alias
augmented in rheumatoid arthritis 2; AURA2; Cancer Osaka thyroid oncogene; cancer Osaka thyroid, oncogene; CCOT; c-COT; COT; cot (cancer Osaka thyroid) oncogene; COT proto-oncogene serine/threonine-protein kinase; Cot/Tpl2; D17TPL2; EC 1.14.16.2; Est; Estf; Ewing sarcoma transformant; FLJ10486; M3K8; MAP3K 8; Map3k8; MEKK8; mitogen activated protein kinase kinase kinase 8; mitogen-activated protein kinase kinase kinase 8; Protein kinase cot; Proto-oncogene c-Cot; proto-oncogene serine/threoine protein kinase; serine/threonine kinase (Tpl-2); serine/threonine-protein kinase cot; TH isoform 3; TH isoform a; TH-4; TPL 2; Tpl2; TPL-2; Tumor progression locus 2; TY3H; TYH
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
116596, 1326, 26410
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P41279, Q07174, Q63562
Gene Symbols
MAP3K8
Immunogen
A synthesized peptide derived from human MAP3K8(Accession P41279), corresponding to amino acid residues around phosphorylated Thr290.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of MAP3K8/COT only when phosphorylated at Threonine 290
- MAP3K8 (COT) is a serine/threonine kinase which can activate both the MAP and JNK kinase pathways and plays a role in the cell cycle
- Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase (MAPKKK or MEKK)
- MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK
- The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells
- MEKK8 is able to activate NF-kappa-B 1 by stimulating proteasome-mediated proteolysis of NF-kappa-B 1/p105
- This cytoplasmic protein is expressed in several normal tissues and human tumor-derived cell lines
- The 58 kDa form is activated specifically during the S and G2/M phases of the cell cycle
- The longer form undergoes phosphorylation on Ser residues mainly, and the shorter form on both Ser and Thr residues.
Compare Similar Items
Show Difference
Antigen: Phospho-TPL2 (Thr290)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MAP3K8
Gene Alias: augmented in rheumatoid arthritis 2; AURA2; Cancer Osaka thyroid oncogene; cancer Osaka thyroid, oncogene; CCOT; c-COT; COT; cot (cancer Osaka thyroid) oncogene; COT proto-oncogene serine/threonine-protein kinase; Cot/Tpl2; D17TPL2; EC 1.14.16.2; Est; Estf; Ewing sarcoma transformant; FLJ10486; M3K8; MAP3K 8; Map3k8; MEKK8; mitogen activated protein kinase kinase kinase 8; mitogen-activated protein kinase kinase kinase 8; Protein kinase cot; Proto-oncogene c-Cot; proto-oncogene serine/threoine protein kinase; serine/threonine kinase (Tpl-2); serine/threonine-protein kinase cot; TH isoform 3; TH isoform a; TH-4; TPL 2; Tpl2; TPL-2; Tumor progression locus 2; TY3H; TYH
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 116596, 1326, 26410
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P41279, Q07174, Q63562
Gene Symbols: MAP3K8
Immunogen: A synthesized peptide derived from human MAP3K8(Accession P41279), corresponding to amino acid residues around phosphorylated Thr290.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-TPL2 (Thr290)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MAP3K8
Gene Alias:
augmented in rheumatoid arthritis 2; AURA2; Cancer Osaka thyroid oncogene; cancer Osaka thyroid, oncogene; CCOT; c-COT; COT; cot (cancer Osaka thyroid) oncogene; COT proto-oncogene serine/threonine-protein kinase; Cot/Tpl2; D17TPL2; EC 1.14.16.2; Est; Estf; Ewing sarcoma transformant; FLJ10486; M3K8; MAP3K 8; Map3k8; MEKK8; mitogen activated protein kinase kinase kinase 8; mitogen-activated protein kinase kinase kinase 8; Protein kinase cot; Proto-oncogene c-Cot; proto-oncogene serine/threoine protein kinase; serine/threonine kinase (Tpl-2); serine/threonine-protein kinase cot; TH isoform 3; TH isoform a; TH-4; TPL 2; Tpl2; TPL-2; Tumor progression locus 2; TY3H; TYH
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
116596, 1326, 26410
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P41279, Q07174, Q63562
Gene Symbols:
MAP3K8
Immunogen:
A synthesized peptide derived from human MAP3K8(Accession P41279), corresponding to amino acid residues around phosphorylated Thr290.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-STAT6 (Tyr641)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: STAT6
Gene Alias: 12S1644; D12S1644; IL4 STAT; IL-4 Stat; IL-4-STAT; signal transducer and activator of transcription 6; signal transducer and activator of transcription 6, interleukin-4 induced; signal transducer and transcription activator 6; STAT; STAT, interleukin4-induced; Stat6; STAT-6; STAT6B; STAT6C; transcription factor IL-4 STAT
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20852, 362896, 6778
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P42226, P52633
Gene Symbols: STAT6
Immunogen: A synthesized peptide derived from human STAT6(Accession P42226), corresponding to amino acid residues around phosphorylated Tyr641.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-STAT6 (Tyr641)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
STAT6
Gene Alias:
12S1644; D12S1644; IL4 STAT; IL-4 Stat; IL-4-STAT; signal transducer and activator of transcription 6; signal transducer and activator of transcription 6, interleukin-4 induced; signal transducer and transcription activator 6; STAT; STAT, interleukin4-induced; Stat6; STAT-6; STAT6B; STAT6C; transcription factor IL-4 STAT
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20852, 362896, 6778
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P42226, P52633
Gene Symbols:
STAT6
Immunogen:
A synthesized peptide derived from human STAT6(Accession P42226), corresponding to amino acid residues around phosphorylated Tyr641.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-STAT6 (Thr645)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: STAT6
Gene Alias: 12S1644; D12S1644; IL4 STAT; IL-4 Stat; IL-4-STAT; signal transducer and activator of transcription 6; signal transducer and activator of transcription 6, interleukin-4 induced; signal transducer and transcription activator 6; STAT; STAT, interleukin4-induced; Stat6; STAT-6; STAT6B; STAT6C; transcription factor IL-4 STAT
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20852, 362896, 6778
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P42226, P52633
Gene Symbols: STAT6
Immunogen: A synthesized peptide derived from human STAT6(Accession P42226), corresponding to amino acid residues around phosphorylated Thr645.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-STAT6 (Thr645)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
STAT6
Gene Alias:
12S1644; D12S1644; IL4 STAT; IL-4 Stat; IL-4-STAT; signal transducer and activator of transcription 6; signal transducer and activator of transcription 6, interleukin-4 induced; signal transducer and transcription activator 6; STAT; STAT, interleukin4-induced; Stat6; STAT-6; STAT6B; STAT6C; transcription factor IL-4 STAT
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20852, 362896, 6778
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P42226, P52633
Gene Symbols:
STAT6
Immunogen:
A synthesized peptide derived from human STAT6(Accession P42226), corresponding to amino acid residues around phosphorylated Thr645.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-STAT5 alpha/beta (Ser726, Ser731)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: STAT5A
Gene Alias: AA959963; Mammary gland factor; mammary gland factor STAT5A; mammary gland factor STAT5B; mammary gland factor; transcription factor; MGF; Mpf; signal transducer and activator of transcription 5; Signal transducer and activator of transcription 5a; Signal transducer and activator of transcription 5B; STA5B; STAT; STAT5; Stat5a; Stat5b; transcription factor STAT5B
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20850, 20851, 24918, 25126, 6776, 6777
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P42229, P42230, P42232, P51692, P52632, Q62771
Gene Symbols: STAT5A, STAT5B
Immunogen: A synthesized peptide derived from human STAT5A(Accession P42229), corresponding to amino acid residues around phosphorylated Ser726.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-STAT5 alpha/beta (Ser726, Ser731)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
STAT5A
Gene Alias:
AA959963; Mammary gland factor; mammary gland factor STAT5A; mammary gland factor STAT5B; mammary gland factor; transcription factor; MGF; Mpf; signal transducer and activator of transcription 5; Signal transducer and activator of transcription 5a; Signal transducer and activator of transcription 5B; STA5B; STAT; STAT5; Stat5a; Stat5b; transcription factor STAT5B
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20850, 20851, 24918, 25126, 6776, 6777
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P42229, P42230, P42232, P51692, P52632, Q62771
Gene Symbols:
STAT5A, STAT5B
Immunogen:
A synthesized peptide derived from human STAT5A(Accession P42229), corresponding to amino acid residues around phosphorylated Ser726.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG