PIPA5104978
Phospho-FOXO1 (Ser319) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5104978-Each-of-1 | In Stock | ₹ 44,191.74 |
PIPA5104978 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,191.74
GST (18%): ₹ 7,954.513
Total Price: ₹ 52,146.253
Antigen
Phospho-FOXO1 (Ser319)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
FOXO1
Gene Alias
Afxh; AI876417; FKH1; FKHR; Fkhr1; forkhead box O1; forkhead box O1 a; forkhead box O1a; forkhead box O1A (rhabdomyosarcoma); forkhead box protein O1; forkhead box protein O1; LOW QUALITY PROTEIN: forkhead box protein O1; forkhead box protein O1A; Forkhead box protein O1-A; Forkhead in rhabdomyosarcoma; forkhead protein 1; forkhead protein FKHR; forkhead, Drosophila, homolog of, in rhabdomyosarcoma; fox family transcription factor FoxO1a.1; FOX01A; foxhead box protein O1-A; foxo1; FOXO1A; FoxO1a.1; member of FKHR-subclass forkhead/winged helix family; zgc:153388
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
2308, 56458, 84482
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
G3V7R4, Q12778, Q9R1E0
Gene Symbols
FOXO1
Immunogen
A synthesized peptide derived from human FOXO1(Accession Q12778), corresponding to amino acid residues around phosphorylated Ser319.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of FOXO1A only when phosphorylated at Serine 319
- FOXO1 (FKHR, ForKHead Box 01) is a member in a subfamily of the forkhead homeotic gene family of transcription factors
- Recent experiments have shown that FOXO1 can act as either a coactivator or a corepressor of nuclear receptor activity that is mediated through the LXXLL motif found in the carboxyl terminal region of the FKHR protein
- Association of FOXO1 with PAX3 has been implicated in alveolar rhabdomyosarcoma
- Recent studies link the anti-tumor activity of FOXO1, the process of autophagy and myogenic growth and differentiation
- FOXO1 is the main target of insulin signaling that regulated the metabolic homeostasis in response to oxidative stress
- FOXO1 binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'- TT[G/A]TTTAC-3'
- FOXO1 is a regulator of redox balance, osteoblast numbers and controls bone mass
- Further, FOXO1 orchestrates the endocrine function of the skeleton in regulating glucose metabolism, and suppresses the transcriptional activity of RUNX2, an upstream activator of osteocalcin/BGLAP
- In hepatocytes, FOXO1 promotes gluconeogenesis by acting together with PPARGC1A to activate the expression of genes such as IGFBP1, G6PC and PPCK1
- FOXO1 is an important regulator of cell death acting downstream of CDK1, PKB/AKT1 and SKT4/MST1.
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Antigen: Phospho-FOXO1 (Ser319)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: FOXO1
Gene Alias: Afxh; AI876417; FKH1; FKHR; Fkhr1; forkhead box O1; forkhead box O1 a; forkhead box O1a; forkhead box O1A (rhabdomyosarcoma); forkhead box protein O1; forkhead box protein O1; LOW QUALITY PROTEIN: forkhead box protein O1; forkhead box protein O1A; Forkhead box protein O1-A; Forkhead in rhabdomyosarcoma; forkhead protein 1; forkhead protein FKHR; forkhead, Drosophila, homolog of, in rhabdomyosarcoma; fox family transcription factor FoxO1a.1; FOX01A; foxhead box protein O1-A; foxo1; FOXO1A; FoxO1a.1; member of FKHR-subclass forkhead/winged helix family; zgc:153388
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2308, 56458, 84482
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: G3V7R4, Q12778, Q9R1E0
Gene Symbols: FOXO1
Immunogen: A synthesized peptide derived from human FOXO1(Accession Q12778), corresponding to amino acid residues around phosphorylated Ser319.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-FOXO1 (Ser319)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
FOXO1
Gene Alias:
Afxh; AI876417; FKH1; FKHR; Fkhr1; forkhead box O1; forkhead box O1 a; forkhead box O1a; forkhead box O1A (rhabdomyosarcoma); forkhead box protein O1; forkhead box protein O1; LOW QUALITY PROTEIN: forkhead box protein O1; forkhead box protein O1A; Forkhead box protein O1-A; Forkhead in rhabdomyosarcoma; forkhead protein 1; forkhead protein FKHR; forkhead, Drosophila, homolog of, in rhabdomyosarcoma; fox family transcription factor FoxO1a.1; FOX01A; foxhead box protein O1-A; foxo1; FOXO1A; FoxO1a.1; member of FKHR-subclass forkhead/winged helix family; zgc:153388
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2308, 56458, 84482
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
G3V7R4, Q12778, Q9R1E0
Gene Symbols:
FOXO1
Immunogen:
A synthesized peptide derived from human FOXO1(Accession Q12778), corresponding to amino acid residues around phosphorylated Ser319.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-NFATC3 (Ser165)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NFATC3
Gene Alias: C80703; D8Ertd281e; NFAC3; NFAT4; NF-AT4; NFATC3; NF-ATc3; NFATx; NFC3; nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3; nuclear factor of activated T-cells 3; nuclear factor of activated T-cells c3 isoform IE-Xa; nuclear factor of activated T-cells, cytoplasmic 3; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3; T cell transcription factor NFAT4; T-cell transcription factor NFAT4
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18021, 361400, 4775
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P97305, Q12968
Gene Symbols: NFATC3
Immunogen: A synthesized peptide derived from human NFATC3(Accession Q12968), corresponding to amino acid residues around phosphorylated Ser165.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-NFATC3 (Ser165)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NFATC3
Gene Alias:
C80703; D8Ertd281e; NFAC3; NFAT4; NF-AT4; NFATC3; NF-ATc3; NFATx; NFC3; nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3; nuclear factor of activated T-cells 3; nuclear factor of activated T-cells c3 isoform IE-Xa; nuclear factor of activated T-cells, cytoplasmic 3; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3; T cell transcription factor NFAT4; T-cell transcription factor NFAT4
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18021, 361400, 4775
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P97305, Q12968
Gene Symbols:
NFATC3
Immunogen:
A synthesized peptide derived from human NFATC3(Accession Q12968), corresponding to amino acid residues around phosphorylated Ser165.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-PAK1 (Thr212)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Pak1
Gene Alias: activated protein kinase alpha; ADRB2; adriamycin resistance-associated; alpha pak; alpha-PAK; ARA; AW045634; Beta-PAK; bPAK; CDC42/RAC effector kinase PAK-A; C-t-PAK2; EC 2.7.11.1; gamma-PAK; kinase PAK1; MGC130000; MGC130001; MRX30; MRX47; Oligophrenin-3; OPHN3; p21 (CDKN1A)-activated kinase 1; p21 (CDKN1A)-activated kinase 2; p21 (CDKN1A)-activated kinase 3; p21 (RAC1) activated kinase 1; p21 (RAC1) activated kinase 2; p21 (RAC1) activated kinase 3; p21 protein (Cdc42/Rac)-activated kinase 1; p21 protein (Cdc42/Rac)-activated kinase 2; p21 protein (Cdc42/Rac)-activated kinase 3; p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast); p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related); p21-activated kinase 1; p21-activated kinase 2; p21-activated kinase 3; p27; p34; p58; p65-PAK; p68-PAK; PAK 1; PAK1; PAK-1; PAK1B; PAK2; PAK-2; PAK-2p27; PAK-2p34; PAK3; PAK-3; PAK3beta; PAK65; Paka; PAKalpha; PAKgamma; protein kinase MUK2; S6/H4 kinase; serine/threonine-protein kinase PAK 1; Serine/threonine-protein kinase PAK 2; serine/threonine-protein kinase PAK 3; STE20 homolog, yeast
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18479, 29431, 5058
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: O88643, P35465, Q13153
Gene Symbols: Pak1
Immunogen: A synthesized peptide derived from human PAK1(Accession Q13153), corresponding to amino acid residues around phosphorylated Thr212.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-PAK1 (Thr212)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Pak1
Gene Alias:
activated protein kinase alpha; ADRB2; adriamycin resistance-associated; alpha pak; alpha-PAK; ARA; AW045634; Beta-PAK; bPAK; CDC42/RAC effector kinase PAK-A; C-t-PAK2; EC 2.7.11.1; gamma-PAK; kinase PAK1; MGC130000; MGC130001; MRX30; MRX47; Oligophrenin-3; OPHN3; p21 (CDKN1A)-activated kinase 1; p21 (CDKN1A)-activated kinase 2; p21 (CDKN1A)-activated kinase 3; p21 (RAC1) activated kinase 1; p21 (RAC1) activated kinase 2; p21 (RAC1) activated kinase 3; p21 protein (Cdc42/Rac)-activated kinase 1; p21 protein (Cdc42/Rac)-activated kinase 2; p21 protein (Cdc42/Rac)-activated kinase 3; p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast); p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related); p21-activated kinase 1; p21-activated kinase 2; p21-activated kinase 3; p27; p34; p58; p65-PAK; p68-PAK; PAK 1; PAK1; PAK-1; PAK1B; PAK2; PAK-2; PAK-2p27; PAK-2p34; PAK3; PAK-3; PAK3beta; PAK65; Paka; PAKalpha; PAKgamma; protein kinase MUK2; S6/H4 kinase; serine/threonine-protein kinase PAK 1; Serine/threonine-protein kinase PAK 2; serine/threonine-protein kinase PAK 3; STE20 homolog, yeast
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18479, 29431, 5058
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
O88643, P35465, Q13153
Gene Symbols:
Pak1
Immunogen:
A synthesized peptide derived from human PAK1(Accession Q13153), corresponding to amino acid residues around phosphorylated Thr212.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-NMDAR2B (Tyr1336)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: GRIN2B
Gene Alias: AW490526; EIEE27; GluN2B; GluRepsilon2; glutamate [NMDA] receptor subunit epsilon-2; glutamate ionotropic receptor NMDA type subunit 2B; glutamate receptor; glutamate receptor ionotropic, NMDA 2B; glutamate receptor subunit epsilon-2; glutamate receptor, ionotropic, NMDA2B; glutamate receptor, ionotropic, NMDA2B (epsilon 2); glutamate receptor, ionotropic, N-methyl D-aspartate 2B; GRIN 2B; GRIN2B; HGNC:4586; hNR 3; hNR3; LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 2B; MGC142178; MGC142180; MRD6; Nmdar2b; NMDE2; NME2; N-methyl D-aspartate receptor 2B; N-methyl D-aspartate receptor subtype 2B; N-methyl-D-aspartate receptor subunit 2B; N-methyl-D-aspartate receptor subunit 3; NR2B; NR3
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14812, 24410, 2904
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q00960, Q01097, Q13224
Gene Symbols: GRIN2B
Immunogen: A synthesized peptide derived from human GRIN2B(Accession Q13224), corresponding to amino acid residues around phosphorylated Tyr1336.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-NMDAR2B (Tyr1336)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
GRIN2B
Gene Alias:
AW490526; EIEE27; GluN2B; GluRepsilon2; glutamate [NMDA] receptor subunit epsilon-2; glutamate ionotropic receptor NMDA type subunit 2B; glutamate receptor; glutamate receptor ionotropic, NMDA 2B; glutamate receptor subunit epsilon-2; glutamate receptor, ionotropic, NMDA2B; glutamate receptor, ionotropic, NMDA2B (epsilon 2); glutamate receptor, ionotropic, N-methyl D-aspartate 2B; GRIN 2B; GRIN2B; HGNC:4586; hNR 3; hNR3; LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 2B; MGC142178; MGC142180; MRD6; Nmdar2b; NMDE2; NME2; N-methyl D-aspartate receptor 2B; N-methyl D-aspartate receptor subtype 2B; N-methyl-D-aspartate receptor subunit 2B; N-methyl-D-aspartate receptor subunit 3; NR2B; NR3
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14812, 24410, 2904
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q00960, Q01097, Q13224
Gene Symbols:
GRIN2B
Immunogen:
A synthesized peptide derived from human GRIN2B(Accession Q13224), corresponding to amino acid residues around phosphorylated Tyr1336.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG