PIPA5104999

Phospho-IkappaB beta (Ser23) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5104999-Each-of-1 In Stock ₹ 42,394.98

PIPA5104999 - Each of 1

₹ 42,394.98

In Stock

Quantity

1

Base Price: ₹ 42,394.98

GST (18%): ₹ 7,631.096

Total Price: ₹ 50,026.076

Antigen

Phospho-IkappaB beta (Ser23)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NFKBIB

Gene Alias

I kappa B beta; I(Kappa)B(beta); ikappaBbeta; I-kappa-B-beta; IkB; IKB B; IKB beta; Ikbb; ikB-B; IkBbeta; ikB-beta; NF kappa BIB; NF-kappa-B inhibitor beta; NF-kappa-BIB; NFKB inhibitor beta; NFKBIB; nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, beta; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta; Thyroid receptor; thyroid receptor-interacting protein 9; TR-interacting protein 9; TRIP 9; TRIP9; TRIP-9

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

18036, 4793, 81525

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q15653, Q60778, Q9JIA3

Gene Symbols

NFKBIB

Immunogen

A synthesized peptide derived from human NFKBIB(Accession Q15653), corresponding to amino acid residues around phosphorylated Ser23.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA5104946

--

Img

Thermo Scientific

PIPA5104947

--

Img

Thermo Scientific

PIPA5104948

--

Img

Thermo Scientific

PIPA5105436

--

Img

Thermo Scientific

PIPA5104846

--

Img

Thermo Scientific

PIPA5104953

--

Img

Thermo Scientific

PIPA5105322

--

Img

Thermo Scientific

PIPA5104952

--

Description

  • Antibody detects endogenous levels of IKB beta only when phosphorylated at Serine 23
  • The NF-kB/Rel transcription factors are present in the cytosol in an inactive state, complexed with the inhibitory IkB proteins
  • Most agents that activate NF-kB do so through a common pathway based on phosphorylation-induced, proteasome-mediated degradation of IkB
  • The key regulatory step in this pathway involves activation of a high molecular weight IkB kinase (IKK) complex whose catalysis is generally carried out by three tightly associated IKK subunits
  • IKK alpha and IKK beta serve as the catalytic subunits of the kinase and IKK gamma serves as the regulatory subunit
  • Activation of IKK depends upon phosphorylation at Ser177 and Ser181 in the activation loop of IKK beta (Ser176 and Ser180 in IKK alpha), which causes conformational changes, resulting in kinase activation.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5104999

--


Antigen:
Phospho-IkappaB beta (Ser23)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NFKBIB

Gene Alias:
I kappa B beta; I(Kappa)B(beta); ikappaBbeta; I-kappa-B-beta; IkB; IKB B; IKB beta; Ikbb; ikB-B; IkBbeta; ikB-beta; NF kappa BIB; NF-kappa-B inhibitor beta; NF-kappa-BIB; NFKB inhibitor beta; NFKBIB; nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, beta; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta; Thyroid receptor; thyroid receptor-interacting protein 9; TR-interacting protein 9; TRIP 9; TRIP9; TRIP-9

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18036, 4793, 81525

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q15653, Q60778, Q9JIA3

Gene Symbols:
NFKBIB

Immunogen:
A synthesized peptide derived from human NFKBIB(Accession Q15653), corresponding to amino acid residues around phosphorylated Ser23.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105000

--


Antigen:
Phospho-SMAD2 (Ser467)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SMAD2

Gene Alias:
7120426M23Rik; EGK_09664; hMAD-2; hSMAD2; JV18; JV18-1; MAD; MAD homolog 2; Mad protein homolog; Madh2; Madr2; Mad-related protein 2; MGC22139; MGC34440; mMad2; mother against DPP homolog 2; mothers against decapentaplegic homolog 2; Mothers against decapentaplegic-like protein 2; mothers against DPP homolog 2; pSMAD2; Sma- and Mad-related protein 2; SMAD; SMAD 2; SMAD family member 2; SMAD, mothers against DPP homolog 2; Smad2; Smad-2; Smad2Deltaexon3

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17126, 29357, 4087

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O70436, Q15796, Q62432

Gene Symbols:
SMAD2

Immunogen:
A synthesized peptide derived from human SMAD2(Accession Q15796), corresponding to amino acid residues around phosphorylated Ser467.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105003

--


Antigen:
Phospho-SMAD1 (Ser187)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SMAD1

Gene Alias:
AI528653, BSP1, BSP-1, dwarfin-A, Dwf-A, DWFC, hSMAD1, JV41, JV4-1, JV5-1, MAD (mothers against decapentaplegic, Drosophila) homolog 1, MAD homolog 1, MAD homolog1 (mothers against decapentaplegic, Drosophila), MAD, mothers against decapentaplegic homolog 1, Madh1, MADH5, MADR1, Mad-related protein 1, Mlp1, mMad1, mothers against decapentaplegic homolog 1, mothers against DPP homolog 1, mothers-against-DPP-related 1, Mothers-against-DPP-related-1, MusMLP, OTTHUMP00000220456, SMAD, Smad 1, SMAD family member 1, SMAD, mothers against DPP homolog 1, Smad1, SMAD5, TGF-beta signaling protein 1, transforming growth factor-beta signaling protein 1, Transforming growth factor-beta-signaling protein 1

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17125, 4086

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P70340, Q15797

Gene Symbols:
SMAD1

Immunogen:
A synthesized peptide derived from human SMAD1(Accession Q15797), corresponding to amino acid residues around phosphorylated Ser187.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105005

--


Antigen:
Phospho-LKB1 (Thr189)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
STK11

Gene Alias:
AA408040; CAMK group; CAMKL family; hLKB1; liver kinase B1; Liver kinase B1 homolog; LKB 1; LKB1; LKB-1; LKB1(S); Par-4; PJS; polarization-related protein LKB1; R75140; renal carcinoma antigen NY-REN-19; serine/threonine kinase 11; serine/threonine-protein kinase 11; serine/threonine-protein kinase LKB1; serine/threonine-protein kinase STK11; STK11

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20869, 6794

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q15831, Q9WTK7

Gene Symbols:
STK11

Immunogen:
A synthesized peptide derived from human STK11(Accession Q15831), corresponding to amino acid residues around phosphorylated Thr189.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG