PIPA5105213

Phospho-ErbB4 (Tyr984) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5105213-Each-of-1 In Stock ₹ 44,705.10

PIPA5105213 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-ErbB4 (Tyr984)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ERBB4

Gene Alias

4ICD; ALS19; avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4; avian erythroblastosis oncogene B 4; c-erbB-4; erb-b2 receptor tyrosine kinase 4; Erbb4; ERBB4 intracellular domain; ERBB4 transcript variant I12DEL; ERBB4 transcript variant I20DEL; Her4; human epidermal growth factor receptor 4; Mer4; OTTHUMP00000209432; p180erbB4; proto-oncogene-like protein c-ErbB-4; receptor tyrosine kinase; receptor tyrosine-protein kinase erbB-4; s80HER4; Tyro-2; Tyrosine kinase-type cell surface receptor HER4; v-erb-a erythroblastic leukemia viral oncogene homolog 4; v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian); v-erb-b2 avian erythroblastic leukemia viral oncogene 4; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

13869, 2066, 59323

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q15303, Q61527, Q62956

Gene Symbols

ERBB4

Immunogen

A synthesized peptide derived from human ERBB4(Accession Q15303), corresponding to amino acid residues around phosphorylated Tyr984.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of HER4 only when phosphorylated at Tyr984
  • Oncogene ERBB4 (HER4) is a member of the type I receptor protein tyrosine subfamily that includes EGFR, ERBB2, and ERBB3
  • ERBB4 binds and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation
  • ErbB 4 is activated by neuregulins and NTAK (neural and thymus derived activator for ErbB kinases)
  • ErbB 4 is a receptor for heregulin and is capable of mediating HGL-stimulated tyrosine phosphorylation of itself
  • Like other protein kinases, ErbB 4 mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation
  • ErbB 4 is most predominantly expressed in several breast carcinoma cell lines, and in normal skeletal muscle, heart, pituitary, brain, and cerebellum
  • Breast tumor cell lines T47-D, MDA-MB-453, BT-474 and H3396 are found to have the highest levels of mRNA, and intermediate levels are seen in MCF-7, MDAMB-330 and MDA-MB-361
  • Expression of ErbB 4 is low or absent in some breast tumor cell lines such as MDA-MB-231, MDA-MB-157, MDA-MB-468, and SKBR-3
  • ErbB 4 levels have been found to be elevated in certain human tumor cell lines suggesting that it may play a role in some malignancies.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA5105213

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Antigen:
Phospho-ErbB4 (Tyr984)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ERBB4

Gene Alias:
4ICD; ALS19; avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4; avian erythroblastosis oncogene B 4; c-erbB-4; erb-b2 receptor tyrosine kinase 4; Erbb4; ERBB4 intracellular domain; ERBB4 transcript variant I12DEL; ERBB4 transcript variant I20DEL; Her4; human epidermal growth factor receptor 4; Mer4; OTTHUMP00000209432; p180erbB4; proto-oncogene-like protein c-ErbB-4; receptor tyrosine kinase; receptor tyrosine-protein kinase erbB-4; s80HER4; Tyro-2; Tyrosine kinase-type cell surface receptor HER4; v-erb-a erythroblastic leukemia viral oncogene homolog 4; v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian); v-erb-b2 avian erythroblastic leukemia viral oncogene 4; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13869, 2066, 59323

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q15303, Q61527, Q62956

Gene Symbols:
ERBB4

Immunogen:
A synthesized peptide derived from human ERBB4(Accession Q15303), corresponding to amino acid residues around phosphorylated Tyr984.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5105214

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Antigen:
Phospho-IRF4 (Tyr122, Tyr125)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IRF4

Gene Alias:
AI385587; interferon regulatory factor 4; Irf4; IRF-4; LSIRF; Lymphocyte-specific interferon regulatory factor; multiple myeloma oncogene 1; MUM1; NF-EM5; PU.1 interaction partner; Sfpi1/PU.1 interaction partner; SHEP8; Spip; Transcriptional activator PIP

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16364, 291100, 3662

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q15306, Q64287

Gene Symbols:
IRF4

Immunogen:
A synthesized peptide derived from human IRF4(Accession Q15306), corresponding to amino acid residues around phosphorylated Tyr122.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5105215

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Antigen:
Phospho-RSK1 (Thr573)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RPS6KA1

Gene Alias:
90 kDa ribosomal protein S6 kinase 1; dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1); hu-1; MAP kinase-activated protein kinase 1; MAP kinase-activated protein kinase 1a; MAPK-activated protein kinase 1; MAPK-activated protein kinase 1a; MAPKAP kinase 1; MAPKAP kinase 1a; MAPKAPK-1; mapkapk1a; MAPKAPK-1a; p90Rsk; P90-RSK; p90-RSK 1; p90Rsk1; p90-Rsk1; p90S6K; pp90RSK1; ribosomal protein S6 kinase 2 alpha; ribosomal protein S6 kinase 2 beta; ribosomal protein S6 kinase a, polypeptide 1; ribosomal protein S6 kinase A1; ribosomal protein S6 kinase A1 L homeolog; ribosomal protein S6 kinase alpha 1; Ribosomal protein S6 kinase alpha-1; Ribosomal protein S6 kinase II alpha; ribosomal protein S6 kinase II beta; ribosomal protein S6 kinase polypeptide 1; ribosomal protein S6 kinase, 90kD, polypeptide 1; Ribosomal protein S6 kinase, 90kD, 1; ribosomal protein S6 kinase, 90kDa, polypeptide 1; ribosomal protein S6 kinase, 90kDa, polypeptide 1 L homeolog; ribosomal protein S6 kinas

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20111, 6195, 81771

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P18653, Q15418, Q63531

Gene Symbols:
RPS6KA1

Immunogen:
A synthesized peptide derived from human RPS6KA1(Accession Q15418), corresponding to amino acid residues around phosphorylated Thr573.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5105217

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Antigen:
Phospho-GKAP1 (Ser25)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Gkap1

Gene Alias:
42 kD cGMP-dependent protein kinase anchoring protein; 42kDa; 4933400B15Rik; cGMP-dependent protein kinase anchoring protein; cGMP-dependent protein kinase anchoring protein 42kDa; cGMP-dependent protein kinase-anchoring protein of 42 kDa; D13Ertd340e; FKSG21; G kinase anchoring protein 1; G kinase-anchoring protein 1; GKAP1; Gkap42; protein kinase anchoring protein GKAP42

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
361202, 56278, 80318

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q5VSY0, Q5XIG5, Q9JMB0

Gene Symbols:
Gkap1

Immunogen:
A synthesized peptide derived from human GKAP1(Accession Q5VSY0), corresponding to amino acid residues around phosphorylated Ser25.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG