PIPA5105249

SOS1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5105249-Each-of-1 In Stock ₹ 44,705.10

PIPA5105249 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

SOS1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SOS1

Gene Alias

4430401P03Rik; 9630010N06; AI449023; G GINGF; GF1; GGF1; GINGF; gingival fibromatosis; gingival fibromatosis, hereditary, 1; guanine nucleotide exchange factor; guanine nucleotide releasing factor; HGF; NS4; ras guanine exchange factor; son of sevenless homolog 1; Son of sevenless homolog 1 (Drosophila); son-of-sevenless 1; SOS Ras/Rac guanine nucleotide exchange factor 1; SOS1; SOS-1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20662, 313845, 6654

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q07889, Q62245

Gene Symbols

SOS1

Immunogen

A synthesized peptide derived from human SOS1(Accession Q07889), corresponding to amino acid residues L1056-D1106.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total SOS1
  • Son of sevenless (SOS) is a guanine nucleotide exchange factor that activates Ras in response to growth factor stimulation
  • Sos1, and its closely related Sos2 paralog, are comprised of an N-terminal histone-binding domain, a RacGEF catalytic (DH) domain juxtaposed with a PH domain, a Ras exchanger motif (REM) domain, a RasGEF catalytic domain, and a C-terminal proline-rich region
  • Sos1 catalyzes the GDP-GTP exchange within the membrane-bound GTPase Ras and thereby switches on a key signaling circuit that involves the activation of MAPK cascade central to cellular proliferation, survival and differentiation
  • Growth factor stimulation rapidly induces the phosphorylation of Sos on multiple serine and threonine sites
  • Phosphorylation of residues within the Sos C-terminus by the MAP/ERK kinase disrupts the Grb2-Sos complex.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5105249

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Antigen:
SOS1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SOS1

Gene Alias:
4430401P03Rik; 9630010N06; AI449023; G GINGF; GF1; GGF1; GINGF; gingival fibromatosis; gingival fibromatosis, hereditary, 1; guanine nucleotide exchange factor; guanine nucleotide releasing factor; HGF; NS4; ras guanine exchange factor; son of sevenless homolog 1; Son of sevenless homolog 1 (Drosophila); son-of-sevenless 1; SOS Ras/Rac guanine nucleotide exchange factor 1; SOS1; SOS-1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20662, 313845, 6654

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q07889, Q62245

Gene Symbols:
SOS1

Immunogen:
A synthesized peptide derived from human SOS1(Accession Q07889), corresponding to amino acid residues L1056-D1106.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105251

--


Antigen:
PCAF

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KAT2B

Gene Alias:
A930006P13Rik; AI461839; AW536563; CAF; CREBBP-associated factor; histone acetylase PCAF; Histone acetyltransferase KAT2B; histone acetyltransferase PCAF; K(lysine) acetyltransferase 2B; Kat2b; Lysine acetyltransferase 2B; P/ PCAF; P/CAF; P300/CBP-associated factor; Pcaf; Spermidine acetyltransferase KAT2B

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18519, 301164, 8850

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q92831, Q9JHD1

Gene Symbols:
KAT2B

Immunogen:
A synthesized peptide derived from human KAT2B(Accession Q92831), corresponding to amino acid residues I703-K753.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105252

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Antigen:
Naked1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NKD1

Gene Alias:
2810434J10Rik; 9030215G15Rik; Dvl-binding protein; hNkd; hNkd1; mNkd; mNkd1; naked cuticle 1 homolog; naked cuticle 1 homolog (Drosophila); naked cuticle homolog 1; naked cuticle homolog 1 (Drosophila); naked cuticle-1; Naked1; naked-1; Nkd; NKD1; PP7246; Protein naked cuticle homolog 1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
364952, 85407, 93960

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q969G9, Q99MH6

Gene Symbols:
NKD1

Immunogen:
A synthesized peptide derived from human NKD1(Accession Q969G9), corresponding to amino acid residues D322-G372.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105253

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Antigen:
Naked2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Nkd2

Gene Alias:
2210403L10Rik; AW212591; Dvl-binding protein NKD2; hNkd2; mNkd2; naked cuticle 1 homolog; naked cuticle 2 homolog; naked cuticle 2 homolog (Drosophila); naked cuticle homolog 2; naked cuticle homolog 2 (Drosophila); naked cuticle-2; Naked2; naked-2; Nkd2; Protein naked cuticle homolog 2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
308068, 72293, 85409

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q8VE28, Q969F2

Gene Symbols:
Nkd2

Immunogen:
A synthesized peptide derived from human NKD2(Accession Q969F2), corresponding to amino acid residues R221-Q271.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG