PIPA5105291
SIAH2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5105291-Each-of-1 | In Stock | ₹ 45,560.70 |
PIPA5105291 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,560.70
GST (18%): ₹ 8,200.926
Total Price: ₹ 53,761.626
Antigen
SIAH2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SIAH2
Gene Alias
AA415433; E3 ubiquitin-protein ligase SIAH2; EC 6.3.2; hSiah2; mSiah2; RING-type E3 ubiquitin transferase SIAH2; seven in absentia 2; seven in absentia homolog 2; siah E3 ubiquitin protein ligase 2; SIAH2; siah-2; Sinh2
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
140593, 20439, 6478
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
O43255, Q06986, Q8R4T2
Gene Symbols
SIAH2
Immunogen
A synthesized peptide derived from human SIAH2(Accession O43255), corresponding to amino acid residues F246-C296.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total SIAH2
- SIAH-2 (seven in absentia homolog 2) is an E3 ligase that catalyzes ubiquitination and proteasome-mediated degradation of protein substrates
- SIAH-2 encodes a 324 amino acid protein that shares 77% identity with human SIAH-1 and 68% identity with the Drosophila sina (seven in absentia) gene, on which development of the Drosophila R7 photoreceptor is dependent
- SIAH-2 targets TRAF2 (which regulates cell responses to stress and cytokines through the regulation of key stress-signaling cascades) for degradation under stress conditions such as hypoxia
- It targets HIF-1 alpha prolyl hydroxylase 3 (PHD3) for degradation upon exposure to hypoxic conditions, which coincides with an increase in SIAH-2 transcription
- SIAH-2 can decrease TNF-alpha-dependent induction of JNK activity and transcriptional activation of NFkB
- SIAH-2 null mice subjected to hypoxia display an impaired respiratory response and reduced levels of hemoglobin.
Compare Similar Items
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Antigen: SIAH2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SIAH2
Gene Alias: AA415433; E3 ubiquitin-protein ligase SIAH2; EC 6.3.2; hSiah2; mSiah2; RING-type E3 ubiquitin transferase SIAH2; seven in absentia 2; seven in absentia homolog 2; siah E3 ubiquitin protein ligase 2; SIAH2; siah-2; Sinh2
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 140593, 20439, 6478
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: O43255, Q06986, Q8R4T2
Gene Symbols: SIAH2
Immunogen: A synthesized peptide derived from human SIAH2(Accession O43255), corresponding to amino acid residues F246-C296.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
SIAH2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SIAH2
Gene Alias:
AA415433; E3 ubiquitin-protein ligase SIAH2; EC 6.3.2; hSiah2; mSiah2; RING-type E3 ubiquitin transferase SIAH2; seven in absentia 2; seven in absentia homolog 2; siah E3 ubiquitin protein ligase 2; SIAH2; siah-2; Sinh2
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
140593, 20439, 6478
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
O43255, Q06986, Q8R4T2
Gene Symbols:
SIAH2
Immunogen:
A synthesized peptide derived from human SIAH2(Accession O43255), corresponding to amino acid residues F246-C296.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: GABRB1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Gabrb1
Gene Alias: AW061132; B230208N19Rik; GABA beta subunit; GABA(A) receptor; GABA(A) receptor subunit beta-1; GABA(A) receptor, beta 1; GABA(A)R beta-1; GABA-RB; Gabrb1; Gabrb-1; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) A receptor, beta 1; gamma-aminobutyric acid (GABA) A receptor, subunit beta 1; gamma-aminobutyric acid (GABA-A) receptor, subunit beta 1; gamma-aminobutyric acid A receptor beta 1; Gamma-aminobutyric acid receptor beta 1; gamma-aminobutyric acid receptor subunit beta-1; gamma-aminobutyric acid receptor, subunit beta 1; gamma-aminobutyric acid type A receptor beta1 subunit; gamma-aminobutyric acid type A receptor subunit beta1; GARB1; GBRB1; si:dkey-20i10.4
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14400, 25450, 2560
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P15431, P18505, P50571
Gene Symbols: Gabrb1
Immunogen: A synthesized peptide derived from human GABRB1(Accession P18505), corresponding to amino acid residues L408-P458.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
GABRB1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Gabrb1
Gene Alias:
AW061132; B230208N19Rik; GABA beta subunit; GABA(A) receptor; GABA(A) receptor subunit beta-1; GABA(A) receptor, beta 1; GABA(A)R beta-1; GABA-RB; Gabrb1; Gabrb-1; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) A receptor, beta 1; gamma-aminobutyric acid (GABA) A receptor, subunit beta 1; gamma-aminobutyric acid (GABA-A) receptor, subunit beta 1; gamma-aminobutyric acid A receptor beta 1; Gamma-aminobutyric acid receptor beta 1; gamma-aminobutyric acid receptor subunit beta-1; gamma-aminobutyric acid receptor, subunit beta 1; gamma-aminobutyric acid type A receptor beta1 subunit; gamma-aminobutyric acid type A receptor subunit beta1; GARB1; GBRB1; si:dkey-20i10.4
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14400, 25450, 2560
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P15431, P18505, P50571
Gene Symbols:
Gabrb1
Immunogen:
A synthesized peptide derived from human GABRB1(Accession P18505), corresponding to amino acid residues L408-P458.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: GATA3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: GATA3
Gene Alias: EGK_19445; GATA binding factor-3; GATA binding protein 3; GATA binding protein-3; GATA3; Gata-3; GATA-binding factor 3; GATA-binding protein 3; HDR; HDRS; jal; MGC2346; MGC5199; MGC5445; Trans-acting T-cell-specific transcription factor GATA-3; Transacting T-cell-specific transcription factor GATA-3
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14462, 2625, 85471
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P23771, P23772
Gene Symbols: GATA3
Immunogen: A synthesized peptide derived from human GATA3(Accession P23771), corresponding to amino acid residues C284-G334.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
GATA3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
GATA3
Gene Alias:
EGK_19445; GATA binding factor-3; GATA binding protein 3; GATA binding protein-3; GATA3; Gata-3; GATA-binding factor 3; GATA-binding protein 3; HDR; HDRS; jal; MGC2346; MGC5199; MGC5445; Trans-acting T-cell-specific transcription factor GATA-3; Transacting T-cell-specific transcription factor GATA-3
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14462, 2625, 85471
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P23771, P23772
Gene Symbols:
GATA3
Immunogen:
A synthesized peptide derived from human GATA3(Accession P23771), corresponding to amino acid residues C284-G334.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: CaMKII beta/gamma/delta
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Camk2b
Gene Alias: [d]-CaMKII; 2810011D23Rik; 8030469K03Rik; Ca++/calmodulin-dependent protein kinase 2 delta subunit; Ca++/calmodulin-dependent protein kinase II beta subunit; Ca++/calmodulin-dependent protein kinase II delta subunit; Ca++/calmodulin-dependent protein kinase II, delta subunit; Ca2+/calmodulin-dependent protein kinase II; calcium/calmodulin dependent protein kinase II beta; calcium/calmodulin dependent protein kinase II delta; calcium/calmodulin dependent protein kinase II gamma; calcium/calmodulin-dependent protein kinase (CaM kinase) II beta; calcium/calmodulin-dependent protein kinase (CaM kinase) II delta; calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma; calcium/calmodulin-dependent protein kinase II beta; calcium/calmodulin-dependent protein kinase II delta; calcium/calmodulin-dependent protein kinase II gamma; calcium/calmodulin-dependent protein kinase II, beta; calcium/calmodulin-dependent protein kinase II, delta; calcium/calmodulin-dependent protein kinase typ
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 108058, 12323, 12325, 171140, 24245, 24246, 816, 817, 818
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P08413, P11730, P15791, P28652, Q13554, Q13555, Q13557, Q6PHZ2, Q923T9
Gene Symbols: Camk2b, CAMK2D, Camk2g
Immunogen: A synthesized peptide derived from human CaMK2-beta/gamma/delta, corresponding to a region within the internal amino acids.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
CaMKII beta/gamma/delta
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Camk2b
Gene Alias:
[d]-CaMKII; 2810011D23Rik; 8030469K03Rik; Ca++/calmodulin-dependent protein kinase 2 delta subunit; Ca++/calmodulin-dependent protein kinase II beta subunit; Ca++/calmodulin-dependent protein kinase II delta subunit; Ca++/calmodulin-dependent protein kinase II, delta subunit; Ca2+/calmodulin-dependent protein kinase II; calcium/calmodulin dependent protein kinase II beta; calcium/calmodulin dependent protein kinase II delta; calcium/calmodulin dependent protein kinase II gamma; calcium/calmodulin-dependent protein kinase (CaM kinase) II beta; calcium/calmodulin-dependent protein kinase (CaM kinase) II delta; calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma; calcium/calmodulin-dependent protein kinase II beta; calcium/calmodulin-dependent protein kinase II delta; calcium/calmodulin-dependent protein kinase II gamma; calcium/calmodulin-dependent protein kinase II, beta; calcium/calmodulin-dependent protein kinase II, delta; calcium/calmodulin-dependent protein kinase typ
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
108058, 12323, 12325, 171140, 24245, 24246, 816, 817, 818
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P08413, P11730, P15791, P28652, Q13554, Q13555, Q13557, Q6PHZ2, Q923T9
Gene Symbols:
Camk2b, CAMK2D, Camk2g
Immunogen:
A synthesized peptide derived from human CaMK2-beta/gamma/delta, corresponding to a region within the internal amino acids.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG