PIPA5105315

Phospho-KCNH2 (Ser1137) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5105315-Each-of-1 In Stock ₹ 44,705.10

PIPA5105315 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-KCNH2 (Ser1137)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

KCNH2

Gene Alias

AI326795; cerg; c-ERG; cERG; ether-a-go-go related member 2; delayed rectifier potassium channel; derg; Eag homolog; eag related protein 1; eag-related gene; eag-related protein 1; ERG; ERG1; ERG-1; ether-a-go-go related gene potassium channel 1; ether-a-go-go related protein; ether-a-go-go-related gene potassium channel 1; ether-a-go-go-related potassium channel protein; ether-a-go-go-related protein 1; gp-erg; HERG; H-ERG; HERG1; HERG-1; KCNH2; Kv11.1; LQT; Lqt2; M-erg; Merg1; M-erg1; merg1a; merg1b; potassium channel; potassium channel protein ERG; potassium channel protein ERG long isoform; potassium channel protein ERG short isoform; potassium channel, voltage gated eag related subfamily H, member 2; potassium voltage-gated channel subfamily H member 2; potassium voltage-gated channel, subfamily H (eag-related), member 2; ra-erg; RERG; r-ERG; SQT1; ventricular ERG K+ channel subunit; voltage-gated potassium channel 11.1; voltage-gated potassium channel subunit Kv11.1; voltage-gate

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

117018, 16511, 3757

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O08962, O35219, Q12809

Gene Symbols

KCNH2

Immunogen

A synthesized peptide derived from human KCNH2(Accession Q12809), corresponding to amino acid residues around phosphorylated Ser1137.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of KCNH2 only when phosphorylated at Ser1137
  • Human ether-a-go-go related gene (HERG) encodes the pore-forming alpha subunit of the delayed rectifier potassium channel IKr
  • There are two N-terminal splice variants of HERG include the full-length isoform 1 alpha and the shorter isoform 1 beta
  • Isoform 1 beta lacks the PAS motif and deactivates at a faster rate than isoform 1alpha
  • Residues within the C-terminal play a role in channel expression and channel gating, including voltage-dependent activation
  • HERG is expressed in the heart and is more abundantly expressed in the ventricles than in the atria
  • Mutations in the gene encoding HERG increase beat-to-beat variability and early after depolarization
  • These fluctuations facilitate the genesis and propagation of premature heartbeats associated with inheritable long QT syndrome type 2 and short QT syndrome type 1.

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PIPA5105315

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Antigen:
Phospho-KCNH2 (Ser1137)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KCNH2

Gene Alias:
AI326795; cerg; c-ERG; cERG; ether-a-go-go related member 2; delayed rectifier potassium channel; derg; Eag homolog; eag related protein 1; eag-related gene; eag-related protein 1; ERG; ERG1; ERG-1; ether-a-go-go related gene potassium channel 1; ether-a-go-go related protein; ether-a-go-go-related gene potassium channel 1; ether-a-go-go-related potassium channel protein; ether-a-go-go-related protein 1; gp-erg; HERG; H-ERG; HERG1; HERG-1; KCNH2; Kv11.1; LQT; Lqt2; M-erg; Merg1; M-erg1; merg1a; merg1b; potassium channel; potassium channel protein ERG; potassium channel protein ERG long isoform; potassium channel protein ERG short isoform; potassium channel, voltage gated eag related subfamily H, member 2; potassium voltage-gated channel subfamily H member 2; potassium voltage-gated channel, subfamily H (eag-related), member 2; ra-erg; RERG; r-ERG; SQT1; ventricular ERG K+ channel subunit; voltage-gated potassium channel 11.1; voltage-gated potassium channel subunit Kv11.1; voltage-gate

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
117018, 16511, 3757

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O08962, O35219, Q12809

Gene Symbols:
KCNH2

Immunogen:
A synthesized peptide derived from human KCNH2(Accession Q12809), corresponding to amino acid residues around phosphorylated Ser1137.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5105317

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Antigen:
Phospho-KLF5 (Ser303)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KLF5

Gene Alias:
(intestinal Kruppel-like factor; 4930520J07Rik; basic transcription element binding protein 2; basic transcription element binding protein BTEB2; basic transcription element-binding protein 2; BTEB2; BTE-binding protein 2; CKLF; colon krueppel-like factor; colon kruppel-like factor; GC box binding protein 2; GC-box-binding protein 2; IKLF; Intestinal-enriched krueppel-like factor; intestinal-enriched kruppel-like factor; Klf5; Klf5C isoform; Krueppel-like factor 5; Kruppel like factor 5; Kruppel-like factor 5; Kruppel-like factor 5 (intestinal); RP11-505F3.5; transcription factor BTEB2

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12224, 688, 84410

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q13887, Q9Z0Z7

Gene Symbols:
KLF5

Immunogen:
A synthesized peptide derived from human KLF5(Accession Q13887), corresponding to amino acid residues around phosphorylated Ser303.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5105318

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Antigen:
Phospho-KV1.1 (KCNA1) (Ser446)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Kcna1

Gene Alias:
AEMK; AI840627; brain potassium channel protein-1; EA1; HBK1; HUK1; IA; Kca1-1; Kcna; Kcna1; Kcpvd; Kv1.1; MBK1; mceph; megencephaly; MGC126782; MGC138385; MK1; Mk-1; MKI; potassium (K+) channel protein voltage dependent; potassium channel, voltage gated shaker related subfamily A, member 1; potassium voltage gated channel shaker related subfamily member 1; potassium voltage gated channel, shaker related subfamily, member 1; potassium voltage-gated channel subfamily A member 1; potassium voltage-gated channel, shaker-related subfamily, member 1; potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia); RBK1; RBKI; RCK1; Shak; Voltage-gated K(+) channel HuKI; voltage-gated potassium channel HBK1; Voltage-gated potassium channel subunit Kv1.1

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3736

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q09470

Gene Symbols:
Kcna1

Immunogen:
A synthesized peptide derived from human KCNA1(Accession Q09470), corresponding to amino acid residues around phosphorylated Ser446.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA5105321

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Antigen:
Phospho-TRAF7 (Ser61)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TRAF7

Gene Alias:
DKFZp586I021; E3 ubiquitin-protein ligase TRAF7; MGC7807; RFWD1; RGD1559653; ring finger and WD repeat domain 1; ring finger and WD repeat domain 1 isoform 1; RING finger and WD repeat-containing protein 1; RING finger protein 119; RING-type E3 ubiquitin transferase TRAF7; RNF119; TNF receptor associated factor 7; TNF receptor-associated factor 7; TNF receptor-associated factor 7, E3 ubiquitin protein ligase; traf7

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
224619, 360491, 84231

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q6Q0C0, Q922B6

Gene Symbols:
TRAF7

Immunogen:
A synthesized peptide derived from human TRAF7(Accession Q6Q0C0), corresponding to amino acid residues around phosphorylated Ser61.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG