PIPA5105344

Phospho-Occludin (Tyr287) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5105344-Each-of-1 In Stock ₹ 43,592.82

PIPA5105344 - Each of 1

₹ 43,592.82

In Stock

Quantity

1

Base Price: ₹ 43,592.82

GST (18%): ₹ 7,846.708

Total Price: ₹ 51,439.528

Antigen

Phospho-Occludin (Tyr287)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

OCLN

Gene Alias

AI503564; BLCPMG; Occludin; occludin 1B; Ocl; Ocln; phosphatase 1, regulatory subunit 115; PPP1R115; tight junction protein occludin; tight junction structural protein

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100506658, 18260, 83497

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q16625, Q61146, Q6P6T5

Gene Symbols

OCLN

Immunogen

A synthesized peptide derived from human OCLN(Accession Q16625), corresponding to amino acid residues around phosphorylated Tyr287.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of Occludin only when phosphorylated at Tyr287
  • Occludin is a 65 kDa protein that can exist in a variety of phosphorylated forms, ranging up to approximately 82 kDa
  • Occludin is thought to be involved in regulating both the localization and the function of occludin
  • Polyunsaturated fatty acids are known to up-regulate occludin expression, increasing the transendothelial cell resistance and reducing the cellular permeability to large molecules
  • The level of occludin varies greatly depending on tissue; in brain tissue, occludin is highly and continuously expressed at cell-cell contact sites, whereas non-neural tissues show lower expression and discontinuous distribution
  • Overall structural features of the occludin protein are highly conserved in all the species examined
  • Under-expression of tight junction proteins, including occludin, is a key molecular abnormality responsible for the increased permeability of tumor endothelial tight junctions, which contributes to brain tumor edemas.

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Img

Thermo Scientific

PIPA5105344

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Antigen:
Phospho-Occludin (Tyr287)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
OCLN

Gene Alias:
AI503564; BLCPMG; Occludin; occludin 1B; Ocl; Ocln; phosphatase 1, regulatory subunit 115; PPP1R115; tight junction protein occludin; tight junction structural protein

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100506658, 18260, 83497

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q16625, Q61146, Q6P6T5

Gene Symbols:
OCLN

Immunogen:
A synthesized peptide derived from human OCLN(Accession Q16625), corresponding to amino acid residues around phosphorylated Tyr287.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105345

--


Antigen:
Phospho-GLI1 (Thr1074)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GLI1

Gene Alias:
AV235269; GLI; GLI family zinc finger 1; Gli1; GLI-Kruppel family member GLI1; Glioma-associated oncogene; glioma-associated oncogene 1; glioma-associated oncogene homolog; glioma-associated oncogene homolog 1 (zinc finger protein); oncogene GLI; Zfp5; Zfp-5; zinc finger protein 5; zinc finger protein GLI1

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14632, 2735

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P08151, P47806

Gene Symbols:
GLI1

Immunogen:
A synthesized peptide derived from human GLI1(Accession P08151), corresponding to amino acid residues around phosphorylated Thr1074.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105346

--


Antigen:
Phospho-GLI1 (Ser1071)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GLI1

Gene Alias:
AV235269; GLI; GLI family zinc finger 1; Gli1; GLI-Kruppel family member GLI1; Glioma-associated oncogene; glioma-associated oncogene 1; glioma-associated oncogene homolog; glioma-associated oncogene homolog 1 (zinc finger protein); oncogene GLI; Zfp5; Zfp-5; zinc finger protein 5; zinc finger protein GLI1

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14632, 2735

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P08151, P47806

Gene Symbols:
GLI1

Immunogen:
A synthesized peptide derived from human GLI1(Accession P08151), corresponding to amino acid residues around phosphorylated Ser1071.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105347

--


Antigen:
Phospho-GLI2 (Ser234)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GLI2

Gene Alias:
AW546128; CJS; GLI family zinc finger 2; GLI family zinc finger protein 2; GLI2; GLI-Kruppel family member GLI2; glioma-associated oncogene family zinc finger 2; HPE9; oncogene GLI2; PHS2; Tax helper protein; tax helper protein 1; tax helper protein 2; tax-responsive element-2 holding protein; tax-responsive element-25-bp sequence binding protein; Thp; THP1; THP2; zinc finger protein GLI2

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2736

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P10070

Gene Symbols:
GLI2

Immunogen:
A synthesized peptide derived from human GLI2(Accession P10070), corresponding to amino acid residues around phosphorylated Ser234.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG