PIPA5105566

Phospho-FLT3 (Tyr631) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5105566-Each-of-1 In Stock ₹ 44,705.10

PIPA5105566 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-FLT3 (Tyr631)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

FLT3

Gene Alias

B230315G04; CD135; CD135 antigen; fetal liver kinase 2; Fetal liver kinase-2; FL cytokine receptor; FLK2; Flk-2; FLT3; Flt-3; fms related tyrosine kinase 3; FMS-like tyrosine kinase 3; fms-related tyrosine kinase 3; growth factor receptor tyrosine kinase type III; Ly72; OTTHUMP00000214829; Receptor-type tyrosine-protein kinase FLT3; RP11-153M24.3; stem cell tyrosine kinase 1; STK1; STK-1; tyrosine-protein kinase FLT3; tyrosine-protein kinase receptor flk-2; wmfl

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

140635, 14255, 2322

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P36888, Q00342

Gene Symbols

FLT3

Immunogen

A synthesized peptide derived from human FLT3(Accession P36888), corresponding to amino acid residues around phosphorylated Tyr630.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of Flt3 / CD135 only when phosphorylated at Tyr630
  • FLT3 is a tyrosine protein kinase that is a member of the growth factor receptor tyrosine kinase family
  • The receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor
  • The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow
  • Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.

Compare Similar Items

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Thermo Scientific

PIPA5105566

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Antigen:
Phospho-FLT3 (Tyr631)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FLT3

Gene Alias:
B230315G04; CD135; CD135 antigen; fetal liver kinase 2; Fetal liver kinase-2; FL cytokine receptor; FLK2; Flk-2; FLT3; Flt-3; fms related tyrosine kinase 3; FMS-like tyrosine kinase 3; fms-related tyrosine kinase 3; growth factor receptor tyrosine kinase type III; Ly72; OTTHUMP00000214829; Receptor-type tyrosine-protein kinase FLT3; RP11-153M24.3; stem cell tyrosine kinase 1; STK1; STK-1; tyrosine-protein kinase FLT3; tyrosine-protein kinase receptor flk-2; wmfl

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
140635, 14255, 2322

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P36888, Q00342

Gene Symbols:
FLT3

Immunogen:
A synthesized peptide derived from human FLT3(Accession P36888), corresponding to amino acid residues around phosphorylated Tyr630.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5105568

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Antigen:
Phospho-STAT3 (Tyr539)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
STAT3

Gene Alias:
1110034C02Rik; acute phase response factor; acute-phase response factor; ADMIO; ADMIO1; APRF; AW109958; DNA-binding protein APRF; FLJ20882; HIES; MGC16063; signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); signal transducer; activator of transcription; acute-phase response factor; signal transduction and activation of transcription 3; STAT; STAT3; STAT-3; stat3 protein; STAT3b1; STAT3b2; transcription factor; Unknown (protein for MGC:128731); wu:fc15d02; wu:fl59g06; z-Stat3

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20848, 25125, 6774

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P40763, P42227, P52631

Gene Symbols:
STAT3

Immunogen:
A synthesized peptide derived from human STAT3(Accession P40763), corresponding to amino acid residues around phosphorylated Tyr539.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5105574

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Antigen:
Phospho-CrkL (Tyr198)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CRKL

Gene Alias:
1110025F07Rik; AA589403; AI325100; CRK like proto-oncogene, adaptor protein; CRKL; crkl {ECO:0000312; crk-like protein; crk-like protein {ECO:0000250; Crkol; EMBL:AAH85865.1, ECO:0000312; OTTHUMP00000198539; RGD:1308531}; UniProtKB:P46109}; v-crk avian sarcoma virus CT10 oncogene homolog-like; v-crk sarcoma virus CT10 oncogene homolog (avian)-like; v-crk sarcoma virus CT10 oncogene homolog-like

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12929, 1399, 287942

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P46109, P47941, Q5U2U2

Gene Symbols:
CRKL

Immunogen:
A synthesized peptide derived from human CRKL(Accession P46109), corresponding to amino acid residues around phosphorylated Tyr198.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5105576

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Antigen:
Phospho-MAPKAPK2 (Thr334)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAPKAPK2

Gene Alias:
AA960234; MAP kinase-activated protein kinase 2; MAPK activated protein kinase 2; MAPK-activated protein kinase 2; MAPKAP kinase 2; Mapkapk2; MAPKAP-K2; MAPKAPK-2; mitogen-activated protein kinase-activated protein kinase 2; MK2; MK-2; Rps6kc1

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17164, 289014, 9261

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P49137, P49138

Gene Symbols:
MAPKAPK2

Immunogen:
A synthesized peptide derived from human MAPKAPK2(Accession P49137), corresponding to amino acid residues around phosphorylated Thr334.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG