PIPA5105630

Phospho-TDP-43 (Ser409) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5105630-Each-of-1 In Stock ₹ 46,929.66

PIPA5105630 - Each of 1

₹ 46,929.66

In Stock

Quantity

1

Base Price: ₹ 46,929.66

GST (18%): ₹ 8,447.339

Total Price: ₹ 55,376.999

Antigen

Phospho-TDP-43 (Ser409)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TARDBP

Gene Alias

1190002A23Rik; ALS10; C85084; hypothetical protein; OTTHUMP00000002171; OTTHUMP00000002173; RCJMB04_5g9; RP4-635E18.2; TAR DNA binding protein; TAR DNA binding protein L homeolog; TAR DNA-binding protein 43; TAR DNA-binding protein-43; tardbp; tardbp.L; Tdp43; TDP-43; wu:fb77f02; wu:fc52g10; XELAEV_18035188mg

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

230908, 23435, 298648

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q13148, Q921F2

Gene Symbols

TARDBP

Immunogen

A synthesized peptide derived from human TARDBP(Accession Q13148), corresponding to amino acid residues around phosphorylated Ser409.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of TDP43 only when phosphorylated at Ser409
  • TDP43 was first identified as a novel cellular protein that binds to HIV-1 virus TAR DNA sequence motifs and acts a transcriptional repressor to the HIV-1 LTR
  • Later experiments revealed that TDP43 also regulates the splicing of exon 9 of the cystic fibrosis transmembrane conductance regular (CFTR), most likely through the association with the UG repeats at the 3&quotee; splice site
  • A hyperphosphorylated, ubiquitinated, and cleaved form of TDP43 known as pathologic TDP43 is the major disease protein in ubiquitin-positive, tau-, and alpha-synuclein-negative frontotemporal dementia (FLTD-U)
  • TDP43 is not related to TRBP1, and RNA binding protein that binds HIV-1 TAR RNA sequences.

Compare Similar Items

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Thermo Scientific

PIPA5105630

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Antigen:
Phospho-TDP-43 (Ser409)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TARDBP

Gene Alias:
1190002A23Rik; ALS10; C85084; hypothetical protein; OTTHUMP00000002171; OTTHUMP00000002173; RCJMB04_5g9; RP4-635E18.2; TAR DNA binding protein; TAR DNA binding protein L homeolog; TAR DNA-binding protein 43; TAR DNA-binding protein-43; tardbp; tardbp.L; Tdp43; TDP-43; wu:fb77f02; wu:fc52g10; XELAEV_18035188mg

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
230908, 23435, 298648

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q13148, Q921F2

Gene Symbols:
TARDBP

Immunogen:
A synthesized peptide derived from human TARDBP(Accession Q13148), corresponding to amino acid residues around phosphorylated Ser409.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105631

--


Antigen:
Phospho-MST2 (Ser316)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
STK3

Gene Alias:
0610042I06Rik; KB-1458E12.1; KRS1; Mammalian STE20-like protein kinase 2; mess1; MST; Mst2; MST-2; MST2/C; MST2/N; Mst3; protein kinase homolog; serine/threonine kinase 3; serine/threonine kinase 3 (STE20 homolog, yeast); serine/threonine kinase 3 (Ste20, yeast homolog); serine/threonine-protein kinase 3; Serine/threonine-protein kinase 3 20kDa subunit; Serine/threonine-protein kinase 3 36kDa subunit; Serine/threonine-protein kinase Krs-1; Ste20; STE20-like kinase MST2; STK3; wu:fc19e11; zgc:55383

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
56274, 65189, 6788

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O54748, Q13188, Q9JI10

Gene Symbols:
STK3

Immunogen:
A synthesized peptide derived from human STK3(Accession Q13188), corresponding to amino acid residues around phosphorylated Ser316.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5105639

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Antigen:
Phospho-4EBP1 (Thr45)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EIF4EBP1

Gene Alias:
4EBP1; 4E-BP1; AA959816; BP-1; eIF4E-binding protein 1; EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1; eukaryotic translation initiation factor 4E-binding protein 1; MGC431; MGC4316; P/OKCL.6; PHAS-1; PHAS-I; Phosphorylated heat- and acid-stable protein regulated by insulin 1

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116636, 13685, 1978

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q13541, Q60876, Q62622

Gene Symbols:
EIF4EBP1

Immunogen:
A synthesized peptide derived from human EIF4EBP1(Accession Q13541), corresponding to amino acid residues around phosphorylated Thr45.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105640

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Antigen:
Phospho-RIP1 (Ser161)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RIPK1

Gene Alias:
cell death protein RIP; D330015H01Rik; FLJ39204; OTTHUMP00000015955; receptor (TNFRSF)-interacting serine-threonine kinase 1; receptor interacting serine/threonine kinase 1; receptor-interacting protein 1; receptor-interacting protein kinase 1; receptor-interacting serine/threonine-protein kinase 1; Rinp; RIP; RIP1; RIP-1; RIP1 (CT); RIPK1; serine/threonine-protein kinase RIP

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19766, 8737

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q13546, Q60855

Gene Symbols:
RIPK1

Immunogen:
A synthesized peptide derived from human RIPK1(Accession Q13546), corresponding to amino acid residues around phosphorylated Ser161.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG