PIPA5105659

Phospho-GRK1 (Ser21) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5105659-Each-of-1 In Stock ₹ 44,705.10

PIPA5105659 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-GRK1 (Ser21)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GRK1

Gene Alias

G protein-coupled receptor kinase 1; G protein-coupled receptpr kinase 1; GPRK1; G-protein coupled receptor kinase 1; G-protein receptor kinase 1; GRK 1a/b; GRK1; GRK1a; rhodopsin kinase; rhodopsin kinase GRK1; Rhok; RK

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

24013, 6011, 81760

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q15835, Q63651, Q9WVL4

Gene Symbols

GRK1

Immunogen

A synthesized peptide derived from human GRK1(Accession Q15835), corresponding to amino acid residues around phosphorylated Ser21.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of GRK1 only when phosphorylated at Ser21
  • GRK1 is a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinases
  • GRK1 mediates rapid desensitization of rod photoreceptors to light by catalyzing phosphorylation of the visual pigment rhodopsin which leads to its deactivation
  • Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2)
  • GRK1 can be phosphorylated by PKA and this reduces the ability of GRK1 to phosphorylate rhodopsin in vitro
  • It is speculated that phosphorylation of GRK1 by PKA in vivo occurs in the dark when cAMP levels in photoreceptor cells are elevated.

Compare Similar Items

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Img

Thermo Scientific

PIPA5105659

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Antigen:
Phospho-GRK1 (Ser21)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GRK1

Gene Alias:
G protein-coupled receptor kinase 1; G protein-coupled receptpr kinase 1; GPRK1; G-protein coupled receptor kinase 1; G-protein receptor kinase 1; GRK 1a/b; GRK1; GRK1a; rhodopsin kinase; rhodopsin kinase GRK1; Rhok; RK

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
24013, 6011, 81760

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q15835, Q63651, Q9WVL4

Gene Symbols:
GRK1

Immunogen:
A synthesized peptide derived from human GRK1(Accession Q15835), corresponding to amino acid residues around phosphorylated Ser21.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5105660

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Antigen:
Phospho-EZH2 (Thr487)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EZH2

Gene Alias:
an; enhancer of zeste 2 polycomb repressive complex 2 subunit; enhancer of zeste homolog 2; enhancer of zeste homolog 2 (Drosophila); ENX 1; ENX1; Enx-1; Enx1h; EZH 2; EZH1; EZH2; EZH-2; EZH2b; histone-lysine N-methyltransferase EZH2; KMT6; KMT6A; lysine N-methyltransferase 6; mKIAA4065; OTTHUMP00000213774; OTTHUMP00000213778; OTTHUMP00000213779; OTTHUMP00000213780; WVS; WVS2

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14056, 2146, 312299

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q15910, Q61188

Gene Symbols:
EZH2

Immunogen:
A synthesized peptide derived from human EZH2(Accession Q15910), corresponding to amino acid residues around phosphorylated Thr487.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5105663

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Antigen:
Phospho-Zyxin (Ser143)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ZYX

Gene Alias:
9530098H06Rik; ESP-2; HED-2; LOW QUALITY PROTEIN: zyxin; R75157; ZYX; Zyxin; zyxin-2

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
114636, 22793, 7791

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q15942, Q62523

Gene Symbols:
ZYX

Immunogen:
A synthesized peptide derived from human ZYX(Accession Q15942), corresponding to amino acid residues around phosphorylated Ser143.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5105664

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Antigen:
Phospho-Nrf2 (Ser344)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NFE2L2

Gene Alias:
AI194320; E4TF1-60; E4TF1A; HEBP1; Nfe2l2; NF-E2-related factor 2; NFE2-related factor 2; NF-E2-related factor-2; NFT2; NRF2; NRF2A; nuclear factor (erythroid-derived 2)-like 2; nuclear factor erythroid 2-like 2; nuclear factor erythroid 2-related factor 2; nuclear factor erythroid-derived 2-like 2; nuclear factor, erythroid 2 like 2; nuclear factor, erythroid 2-like 2; nuclear factor, erythroid derived 2, like 2; Unknown (protein for IMAGE:7945830)

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18024, 4780, 83619

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O54968, Q16236, Q60795

Gene Symbols:
NFE2L2

Immunogen:
A synthesized peptide derived from human NFE2L2(Accession Q16236), corresponding to amino acid residues around phosphorylated Ser344.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG