PIPA5105713

Phospho-TLR4 (Ser800) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5105713-Each-of-1 In Stock ₹ 44,191.74

PIPA5105713 - Each of 1

₹ 44,191.74

In Stock

Quantity

1

Base Price: ₹ 44,191.74

GST (18%): ₹ 7,954.513

Total Price: ₹ 52,146.253

Antigen

Phospho-TLR4 (Ser800)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TLR4

Gene Alias

ARMD10; CD284; EGK_07381; homolog of Drosophila toll; hToll; lipopolysaccharide response; Lps; Ly87; Ran/M1; Rasl2-8; Tlr4; TLR-4; TOLL; toll like receptor 4; toll/interleukin-l receptor (TIR) domain; toll4; toll-like receptor 4; toll-like receptor 4 immunity-related protein; Toll-like receptor 4-like protein; Toll-like receptor4 protein

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

21898, 29260, 7099

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O00206, Q9QUK6, Q9QX05

Gene Symbols

TLR4

Immunogen

A synthesized peptide derived from human TLR4(Accession O00206), corresponding to amino acid residues around phosphorylated Ser800.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of TLR4 only when phosphorylated at Ser800
  • TLR4 is member of the Toll like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity
  • TLRs are highly conserved from Drosophila to humans and share structural and functional similarities
  • This receptor is most abundantly expressed in placenta, and in myelomonocytic subpopulation of the leukocytes
  • Mammalian cells respond to LPS by activating TLR4
  • TLR4 belongs to the multi-protein complex of lipopolysaccharide (LPS) receptor, containing CD14, LY96 and TLR4, and is involved in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria
  • TLR4 aids in the recognition of pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity
  • The various TLRs exhibit different patterns of expression
  • Mutations in the TLR4 gene have been associated with differences in LPS responsiveness
  • Also, several transcript variants of the TLR4 gene have been found, but the protein coding potential of most of them is uncertain
  • TLR4 is expressed by peripheral blood monocytes and a small population of B-cells and is also expressed in human placenta
  • Studies with TLR4-deficient mice indicate that the main ligand for TLR is lipopolysaccharide
  • Consequently, these mice also showed increased susceptibility to Gram-negative sepsis.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA5105713

--


Antigen:
Phospho-TLR4 (Ser800)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TLR4

Gene Alias:
ARMD10; CD284; EGK_07381; homolog of Drosophila toll; hToll; lipopolysaccharide response; Lps; Ly87; Ran/M1; Rasl2-8; Tlr4; TLR-4; TOLL; toll like receptor 4; toll/interleukin-l receptor (TIR) domain; toll4; toll-like receptor 4; toll-like receptor 4 immunity-related protein; Toll-like receptor 4-like protein; Toll-like receptor4 protein

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21898, 29260, 7099

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O00206, Q9QUK6, Q9QX05

Gene Symbols:
TLR4

Immunogen:
A synthesized peptide derived from human TLR4(Accession O00206), corresponding to amino acid residues around phosphorylated Ser800.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5105714

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Antigen:
N-WASP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
WASL

Gene Alias:
2900021I12Rik; 3110031I02Rik; DKFZp779G0847; MGC48327; n wasp; neural Wiskott-Aldrich syndrome protein; NWASP; N-WASP; TRS4; WASL; WASP like actin nucleation promoting factor; WASPB; Wiskott-Aldrich syndrome like; Wiskott-Aldrich syndrome-like; Wiskott-Aldrich syndrome-like (human)

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
73178, 8976

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O00401, Q91YD9

Gene Symbols:
WASL

Immunogen:
A synthesized peptide derived from human WASL(Accession O00401), corresponding to amino acid residues E231-P281.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA5105716

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Antigen:
SETD8

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KMT5A

Gene Alias:
2410195B05Rik; AA617402; AW536475; H4-K20-HMTase; H4-K20-HMTase KMT5A; H4-K20-HMTase SETD8; H4-K20-specific histone methyltransferase; H4K20-specific histone methyltransferase splice variant Set8b; histone methyltransferase Pr-set7/Set8; histone-lysine N-methyltransferase KMT5A; histone-lysine N-methyltransferase SETD8; KMT5A; lysine (K)-specific methyltransferase 5A; lysine methyltransferase 5A; lysine N-methyltransferase 5A; Lysine-specific methylase 5A; N-lysine methyltransferase KMT5A; N-lysine methyltransferase SETD8; PR/SET domain containing protein 8; PR/SET domain-containing protein 07; PR/SET07; PRSET7; PR-Set7; RGD1305893; SET domain containing (lysine methyltransferase) 8; SET domain containing protein 8 variant 1; SET domain containing protein 8 variant 2; SET domain-containing 8; SET domain-containing protein 8; SET07; SET8; SETD8; Unknown (protein for MGC:134426)

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
387893, 67956, 689820

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q2YDW7, Q9NQR1

Gene Symbols:
KMT5A

Immunogen:
A synthesized peptide derived from human KMT5A(Accession Q9NQR1), corresponding to amino acid residues E74-C124.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5105720

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Antigen:
CTNNAL1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CTNNAL1

Gene Alias:
ACRP; AI616177; alpha2-catulin; alpha-catenin related protein; alpha-catenin-related protein; alpha-CATU; Alpha-catulin; AW545119; C86009; catenin (cadherin associated protein), alpha-like 1; catenin (cadherin-associated protein), alpha-like 1; catenin alpha like 1; catenin alpha-like 1; catenin alpha-like protein 1; Catnal1; CLLP; CTNNAL1; RP11-115J22.1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8727

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9UBT7

Gene Symbols:
CTNNAL1

Immunogen:
A synthesized peptide derived from human CTNNAL1(Accession Q9UBT7), corresponding to amino acid residues H412-P462.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG