PIPA5105741

BAP1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5105741-Each-of-1 In Stock ₹ 44,705.10

PIPA5105741 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

BAP1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

BAP1

Gene Alias

2300006C11Rik; AA989761; AW553466; BAP1; Brca1 associated protein 1; BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase); BRCA1-associated protein 1; Cerebral protein 6; cerebral protein-13; DKFZp686N04275; FLJ35406; FLJ37180; HUCEP-13; hucep-6; KIAA0272; mKIAA0272; Ubiquitin carboxyl-terminal hydrolase BAP1; ubiquitin C-terminal hydrolase X4; UCHL2; uch-x4

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

306257, 8314

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

D3ZHS6, Q92560

Gene Symbols

BAP1

Immunogen

A synthesized peptide derived from human BAP1(Accession Q92560), corresponding to amino acid residues L343-Q393.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total BAP1
  • BRCA1-associated protein-1, or BAP1, interacts with the RING finger domain of BRCA1
  • The N-terminal 240 amino acids of the predicted 729-amino acid human protein show homology to ubiquitin C-terminal hydrolases (UCHs), thiol proteases that catalyze proteolytic processing of ubiquitin
  • In addition, BAP1 contains an acidic region, a highly charged C-terminal region, and 2 putative nuclear localization signals
  • BAP1 and BRCA1 associate in vivo and have overlapping subnuclear localization patterns
  • BAP1 enhances BRCA1-mediated inhibition of breast cancer cell growth
  • Northern blot analysis indicates that BAP1 is expressed as a 4-kb mRNA in all human tissues tested, with A 4
  • 8-kb transcript expressed exclusively in testis
  • Northern blot analysis and in situ hybridization reveal that BAP1 and BRCA1 are coexpressed during murine breast development and remodeling
  • The BAP1 gene has been mapped to 3p21
  • 3, a region of loss of heterozygosity for breast cancer as well as frequently deleted in lung carcinomas
  • Intragenic homozygous rearrangements and deletions of BAP1 appear in lung carcinoma cell lines
  • It has been postulated that BAP1 is a tumor suppressor gene that functions in the BRCA1 growth control pathway.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA5105741

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Antigen:
BAP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BAP1

Gene Alias:
2300006C11Rik; AA989761; AW553466; BAP1; Brca1 associated protein 1; BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase); BRCA1-associated protein 1; Cerebral protein 6; cerebral protein-13; DKFZp686N04275; FLJ35406; FLJ37180; HUCEP-13; hucep-6; KIAA0272; mKIAA0272; Ubiquitin carboxyl-terminal hydrolase BAP1; ubiquitin C-terminal hydrolase X4; UCHL2; uch-x4

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
306257, 8314

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
D3ZHS6, Q92560

Gene Symbols:
BAP1

Immunogen:
A synthesized peptide derived from human BAP1(Accession Q92560), corresponding to amino acid residues L343-Q393.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5105742

--


Antigen:
REPS1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
REPS1

Gene Alias:
BB161292; MIG2; RALBP1; RalBP1 associated Eps domain containing 1; RalBP1 associated Eps domain containing protein; ralBP1-associated Eps domain-containing protein 1; RalBP1-interacting protein 1; Reps1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
292944, 85021

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q96D71

Gene Symbols:
REPS1

Immunogen:
A synthesized peptide derived from human REPS1(Accession Q96D71), corresponding to amino acid residues P247-Q297.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5105743

--


Antigen:
DNAJC2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Dnajc2

Gene Alias:
(rat homolog) mouse id-associated protein 1; AU020218; DnaJ (Hsp40) homolog, subfamily C, member 2; DnaJ heat shock protein family (Hsp40) member C2; dnaJ homolog subfamily C member 2; DnaJ homolog subfamily C member 2, N-terminally processed; Dnajc2; Gliosarcoma-related antigen MIDA1; Id associate 1; Mida1; Mouse Id associate 1; M-phase phosphoprotein 11; MPHOSPH11; MPP11; Unknown (protein for MGC:139161); ZRF1; Zrf2; ZUO1; zuotin related factor 1; zuotin related factor 2; zuotin-related factor 1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22791, 27000

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P54103, Q99543

Gene Symbols:
Dnajc2

Immunogen:
A synthesized peptide derived from human DNAJC2(Accession Q99543), corresponding to amino acid residues S23-F73.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5105746

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Antigen:
Phospho-TYK2 (Tyr1054)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TYK2

Gene Alias:
4833430L21Rik; AW540162; BRE1; BRE1A; C79397; hBRE1; IMD35; JTK1; mKIAA4116; Non-receptor tyrosine-protein kinase TYK2; Tyk2; tyrosine kinase 2; tyrosine kinase TYK2

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
54721, 7297

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P29597, Q9R117

Gene Symbols:
TYK2

Immunogen:
A synthesized peptide derived from human TYK2(Accession P29597), corresponding to amino acid residues around phosphorylated Tyr1054.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG