PIPA5105875

Phospho-DYRK2/DYRK4 (Tyr382, Tyr264) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5105875-Each-of-1 In Stock ₹ 40,042.08

PIPA5105875 - Each of 1

₹ 40,042.08

In Stock

Quantity

1

Base Price: ₹ 40,042.08

GST (18%): ₹ 7,207.574

Total Price: ₹ 47,249.654

Antigen

Phospho-DYRK2/DYRK4 (Tyr382, Tyr264)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Dyrk4

Gene Alias

1810038L18Rik; AW049118; dual specificity tyrosine phosphorylation regulated kinase 2; dual specificity tyrosine phosphorylation regulated kinase 4; dual specificity tyrosine-(Y)-phosphorylation regulated kinase 2; dual specificity tyrosine-(Y)-phosphorylation regulated kinase 4; dual specificity tyrosine-phosphorylation-regulated kinase 2; Dual specificity tyrosine-phosphorylation-regulated kinase 4; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4; dyrk2; Dyrk4; Dyrk4a; Dyrk4b; RAD51 associated protein 1; Rad51ap1

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

101320, 312721, 314862, 69181, 8445, 8798

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q5U4C9, Q8BI55, Q92630, Q9NR20

Gene Symbols

DYRK2, Dyrk4

Immunogen

A synthesized peptide derived from human DYRK2(Accession Q92630), corresponding to amino acid residues around phosphorylated Tyr382.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of DYRK2/4 only when phosphorylated at Y382/Y264
  • DYRK2 is a member of the dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family that is thought to be involved in cellular proliferation and apoptosis
  • Under normal conditions, nuclear but not cytoplasmic DYRK2 is ubiquitinated by MDM2, leading to its constitutive degradation
  • However, upon exposure to genotoxic stress, ATM phosphorylates DYRK2, leading to its dissociation from MDM2 and its phosphorylation of p53, thereby inducing apoptosis
  • Recent evidence also suggests that DYRK2 may serve as a scaffold that facilitates assembly of an E3 ubiquitin ligase.

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Thermo Scientific

PIPA5105875

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Antigen:
Phospho-DYRK2/DYRK4 (Tyr382, Tyr264)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Dyrk4

Gene Alias:
1810038L18Rik; AW049118; dual specificity tyrosine phosphorylation regulated kinase 2; dual specificity tyrosine phosphorylation regulated kinase 4; dual specificity tyrosine-(Y)-phosphorylation regulated kinase 2; dual specificity tyrosine-(Y)-phosphorylation regulated kinase 4; dual specificity tyrosine-phosphorylation-regulated kinase 2; Dual specificity tyrosine-phosphorylation-regulated kinase 4; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4; dyrk2; Dyrk4; Dyrk4a; Dyrk4b; RAD51 associated protein 1; Rad51ap1

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
101320, 312721, 314862, 69181, 8445, 8798

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q5U4C9, Q8BI55, Q92630, Q9NR20

Gene Symbols:
DYRK2, Dyrk4

Immunogen:
A synthesized peptide derived from human DYRK2(Accession Q92630), corresponding to amino acid residues around phosphorylated Tyr382.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5105876

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Antigen:
Phospho-EphA8 (Tyr839)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Epha8

Gene Alias:
AW047546; Eek; EK3; epa8; EPH- and ELK-related kinase; EPH- and ELK-related tyrosine kinase; Eph receptor A8; Epha8; EPH-like kinase 3; Ephrin type-A receptor 8; Ephrin type-A receptor 8 precursor (Tyrosine-protein kinase receptor EEK) (EPH-and ELK-related kinase); Hek3; hydroxyaryl-protein kinase; KIAA1459; mKIAA1459; protein-tyrosine kinase; tyrosine-protein kinase receptor EEK; tyrosylprotein kinase

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13842, 2046, 60589

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O09127, P29321, P29322

Gene Symbols:
Epha8

Immunogen:
A synthesized peptide derived from human EPHA8(Accession P29322), corresponding to amino acid residues around phosphorylated Tyr839.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5105878

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Antigen:
Phospho-EphB1/EphB2/EphB3/EphB4 (Tyr600, Tyr602, Tyr614, Tyr596)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EPHB3

Gene Alias:
9330129L11; AI042935; AW456895; AW488255; C130099E04Rik; CAPB; Cek10; Cek5; Cek6; Developmental kinase 2; developmental kinase 5; Developmentally-regulated Eph-related tyrosine kinase; DRT; EK2; EK5; EK6; ELK; Elkh; ELK-related protein tyrosine kinase; elk-related tyrosine kinase; embryonic kinase 2; ENSMUSG00000074119; EPH receptor B1; Eph receptor B2; Eph receptor B2 (ELK-related protein tyrosine kinase); EPH receptor B3; Eph receptor B4; eph tyrosine kinase 2; EPH tyrosine kinase 3; Ephb1; EPHB2; EphB2/CTF1; EphB2/CTF2; Ephb3; EPHB4; EPH-like kinase 2; EPH-like kinase 5; EPH-like kinase 6; EPH-like tyrosine kinase 2; EPH-like tyrosine kinase-2; ephrin receptor EphB4; ephrin type-B receptor 1; Ephrin type-B receptor 2; ephrin type-B receptor 3; Ephrin type-B receptor 4; EPHT2; EPHT3; Epth2; Epth3; ERK; ETECK; ETK2; HEK2; HEK5; HEK6; hepatoma transmembrane kinase; Htk; human embryo kinase 2; Mdk2; mDK-2; MDK5; mDK-5; MYK1; Net; Neural kinase; neuronally-expressed EPH-related tyrosine kinase; Nuk; nuk receptor tyrosine kinase; PCBC; Prkm5; protein-tyrosine kinase HEK5; Qek5; renal carcinoma antigen NY-REN-47; RGD1564232; Sek3; Sek4; soluble EPHB1 variant 1; soluble EPHB4 variant 1; soluble EPHB4 variant 2; soluble EPHB4 variant 3; Tyro11; TYRO5; Tyro6; Tyrosine kinase MYK-1; tyrosine-protein kinase receptor EPH-2; Tyrosine-protein kinase receptor EPH-3; tyrosine-protein kinase receptor HTK; tyrosine-protein kinase receptor SEK-3; Tyrosine-protein kinase receptor SEK-4; tyrosine-protein kinase TYRO11; Tyrosine-protein kinase TYRO5; tyrosine-protein kinase TYRO6

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13844, 13845, 13846, 2047, 2048, 2049, 2050, 24338, 270190, 287989, 313633, 686310

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P09759, P29323, P54753, P54754, P54760, P54761, P54762, P54763, Q8CBF3

Gene Symbols:
Ephb1, Ephb2, EPHB3, EPHB4

Immunogen:
A synthesized peptide derived from human EPHB1(Accession P54762), corresponding to amino acid residues around phosphorylated Tyr596.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5105879

--


Antigen:
Phospho-FER (Tyr714)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FER

Gene Alias:
AV082135; C330004K01Rik; c-FER; EC 2.7.10.2; Feline encephalitis virus-related kinase FER; FER; fer (fms/fps related) protein kinase; fer (fms/fps related) protein kinase, testis specific 2; fer (fps/fes related) tyrosine kinase; FER tyrosine kinase; Fert; Fert2; Flk; Flk_retired; Fujinami poultry sarcoma/Feline sarcoma-related protein Fer; p47; p94-Fer; phosphoprotein NCP94; PPP1R74; protein phosphatase 1, regulatory subunit 74; proto-oncogene c-Fer; proto-oncogene tyrosine-protein kinase Fer; TYK3; Tyrosine kinase 3; tyrosine protein kinase FLK; tyrosine-protein kinase Fer; Tyrosine-protein kinase FLK

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14158, 2241, 301737

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P09760, P16591, P70451

Gene Symbols:
FER

Immunogen:
A synthesized peptide derived from human FER(Accession P16591), corresponding to amino acid residues around phosphorylated Tyr714.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG