PIPA5105901
Phospho-MNK1 (Thr250) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5105901-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5105901 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
Phospho-MNK1 (Thr250)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MKNK1
Gene Alias
2410048M24Rik; MAP kinase interacting serine/threonine kinase 1; MAP kinase signal-integrating kinase 1; MAP kinase-interacting serine/threonine kinase 1; MAP kinase-interacting serine/threonine-protein kinase 1; MAPK signal-integrating kinase 1; MKNK1; Mnk1; OTTHUMP00000009675; OTTHUMP00000009676
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17346, 500526, 8569
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
O08605, Q4G050, Q9BUB5
Gene Symbols
MKNK1
Immunogen
A synthesized peptide derived from human MKNK1(Accession Q9BUB5), corresponding to amino acid residues around phosphorylated Thr250.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of Mnk1 only when phosphorylated at Thr250
- The Map kinase-interacting kinases (MKNK1 and MKNK2) are activated by Map kinases, regulate protein synthesis by phosphroylation eIF4E on Ser209, and may contribute to tumorigenesis
- Overexpression of Mnk2 results in increased phosphorylation of endogenous eIF-4E, showing that it can act as an eIF-4E kinase in vivo
- Mnk2 may play a role in the response to environmental stress and cytokines
- Expression of active mutants of MNK1 and MNK2 in 293 cells diminishes cap-dependent translation relative to cap-independent translation in a transient reporter assay
- Human Mnk2 is homologous to murine Mnk2 (approximately 94% identical) and human Mnk1 (71% identical)
- In vitro phosphorylation studies show that Mnk2 is a significantly better substrate than Mnk1 for extracellular signal-regulated kinase 2 (Erk2), p38MAPKalpha, and p38MAPKbeta.
Compare Similar Items
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Antigen: Phospho-MNK1 (Thr250)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MKNK1
Gene Alias: 2410048M24Rik; MAP kinase interacting serine/threonine kinase 1; MAP kinase signal-integrating kinase 1; MAP kinase-interacting serine/threonine kinase 1; MAP kinase-interacting serine/threonine-protein kinase 1; MAPK signal-integrating kinase 1; MKNK1; Mnk1; OTTHUMP00000009675; OTTHUMP00000009676
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17346, 500526, 8569
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: O08605, Q4G050, Q9BUB5
Gene Symbols: MKNK1
Immunogen: A synthesized peptide derived from human MKNK1(Accession Q9BUB5), corresponding to amino acid residues around phosphorylated Thr250.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-MNK1 (Thr250)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MKNK1
Gene Alias:
2410048M24Rik; MAP kinase interacting serine/threonine kinase 1; MAP kinase signal-integrating kinase 1; MAP kinase-interacting serine/threonine kinase 1; MAP kinase-interacting serine/threonine-protein kinase 1; MAPK signal-integrating kinase 1; MKNK1; Mnk1; OTTHUMP00000009675; OTTHUMP00000009676
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17346, 500526, 8569
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
O08605, Q4G050, Q9BUB5
Gene Symbols:
MKNK1
Immunogen:
A synthesized peptide derived from human MKNK1(Accession Q9BUB5), corresponding to amino acid residues around phosphorylated Thr250.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-MOK (Tyr161)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MOK
Gene Alias: MAPK/MAK/MRK overlapping kinase; MAPK/MAK/MRK/ overlapping kinase; MOK; MOK protein kinase; Rage; RAGE1; RAGE-1; renal cell carcinoma antigen; renal tumor antigen; renal tumor antigen 1; Serine/threonine kinase 30; soluble RAGE; STK30; T/STK 30
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 26448, 362787, 5891
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q9UQ07, Q9WVS4
Gene Symbols: MOK
Immunogen: A synthesized peptide derived from human MOK(Accession Q9UQ07), corresponding to amino acid residues around phosphorylated Tyr161.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-MOK (Tyr161)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MOK
Gene Alias:
MAPK/MAK/MRK overlapping kinase; MAPK/MAK/MRK/ overlapping kinase; MOK; MOK protein kinase; Rage; RAGE1; RAGE-1; renal cell carcinoma antigen; renal tumor antigen; renal tumor antigen 1; Serine/threonine kinase 30; soluble RAGE; STK30; T/STK 30
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
26448, 362787, 5891
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q9UQ07, Q9WVS4
Gene Symbols:
MOK
Immunogen:
A synthesized peptide derived from human MOK(Accession Q9UQ07), corresponding to amino acid residues around phosphorylated Tyr161.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-MSK2 (Ser196)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Rps6ka4
Gene Alias: 1110069D02Rik; 90 kDa ribosomal protein S6 kinase 4; 90kDa; AI848992; Ccdc88b; coiled-coil domain containing 88B; EC 2.7.11.1; kinase MSK2; KS6A4; mitogen- and stress-activated protein kinase 2; mitogen- and stress-activated protein kinase-2; mMSK2; MSK2; Nuclear mitogen- and stress-activated protein kinase 2; ribosomal protein kinase B; ribosomal protein S6 kinase A4; ribosomal protein S6 kinase alpha 4; ribosomal protein S6 kinase alpha-4; ribosomal protein S6 kinase, 90kD, polypeptide 4; ribosomal protein S6 kinase, 90kDa, polypeptide 4; ribosomal protein S6 kinase, polypeptide 4; RLSK; RPS6KA4; RSKB; RSK-B; RSK-like protein kinase; S6K-alpha-4
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 361715, 56613, 8986
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: O75676, Q9Z2B9
Gene Symbols: Rps6ka4
Immunogen: A synthesized peptide derived from human RPS6KA4(Accession O75676), corresponding to amino acid residues around phosphorylated Ser196.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-MSK2 (Ser196)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Rps6ka4
Gene Alias:
1110069D02Rik; 90 kDa ribosomal protein S6 kinase 4; 90kDa; AI848992; Ccdc88b; coiled-coil domain containing 88B; EC 2.7.11.1; kinase MSK2; KS6A4; mitogen- and stress-activated protein kinase 2; mitogen- and stress-activated protein kinase-2; mMSK2; MSK2; Nuclear mitogen- and stress-activated protein kinase 2; ribosomal protein kinase B; ribosomal protein S6 kinase A4; ribosomal protein S6 kinase alpha 4; ribosomal protein S6 kinase alpha-4; ribosomal protein S6 kinase, 90kD, polypeptide 4; ribosomal protein S6 kinase, 90kDa, polypeptide 4; ribosomal protein S6 kinase, polypeptide 4; RLSK; RPS6KA4; RSKB; RSK-B; RSK-like protein kinase; S6K-alpha-4
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
361715, 56613, 8986
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
O75676, Q9Z2B9
Gene Symbols:
Rps6ka4
Immunogen:
A synthesized peptide derived from human RPS6KA4(Accession O75676), corresponding to amino acid residues around phosphorylated Ser196.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-MST3 (Thr18)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: STK24
Gene Alias: 1810013H02Rik; C76483; epididymis secretory protein Li 95; HEL-S-95; Mammalian STE20-like protein kinase 3; Mammalian STE20-like protein kinase 3 C-terminal; Mammalian STE20-like protein kinase 3 N-terminal; mammalian sterile twenty 3 kinase; Mst3; MST-3; MST3/C; MST3/N; MST3B; OTTHUMP00000018594; RGD1561742; RP11-111L24.5; serine/threonine kinase 24; serine/threonine kinase 24 (STE20 homolog, yeast); serine/threonine-protein kinase 24; Serine/threonine-protein kinase 24 12 kDa subunit; Serine/threonine-protein kinase 24 35 kDa subunit; Serine/threonine-protein kinase 24 36 kDa subunit; STE20; STE20-like kinase 3; STE20-like kinase MST3; sterile 20-like kinase 3; STK24; STK3
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 223255, 361092, 8428
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: B0LT89, Q99KH8, Q9Y6E0
Gene Symbols: STK24
Immunogen: A synthesized peptide derived from human STK24(Accession Q9Y6E0), corresponding to amino acid residues around phosphorylated Thr18.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-MST3 (Thr18)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
STK24
Gene Alias:
1810013H02Rik; C76483; epididymis secretory protein Li 95; HEL-S-95; Mammalian STE20-like protein kinase 3; Mammalian STE20-like protein kinase 3 C-terminal; Mammalian STE20-like protein kinase 3 N-terminal; mammalian sterile twenty 3 kinase; Mst3; MST-3; MST3/C; MST3/N; MST3B; OTTHUMP00000018594; RGD1561742; RP11-111L24.5; serine/threonine kinase 24; serine/threonine kinase 24 (STE20 homolog, yeast); serine/threonine-protein kinase 24; Serine/threonine-protein kinase 24 12 kDa subunit; Serine/threonine-protein kinase 24 35 kDa subunit; Serine/threonine-protein kinase 24 36 kDa subunit; STE20; STE20-like kinase 3; STE20-like kinase MST3; sterile 20-like kinase 3; STK24; STK3
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
223255, 361092, 8428
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
B0LT89, Q99KH8, Q9Y6E0
Gene Symbols:
STK24
Immunogen:
A synthesized peptide derived from human STK24(Accession Q9Y6E0), corresponding to amino acid residues around phosphorylated Thr18.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG