PIPA5105996
Phospho-FOXO1 (Ser249) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5105996-Each-of-1 | In Stock | ₹ 45,218.46 |
PIPA5105996 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,218.46
GST (18%): ₹ 8,139.323
Total Price: ₹ 53,357.783
Antigen
Phospho-FOXO1 (Ser249)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
FOXO1
Gene Alias
Afxh; AI876417; FKH1; FKHR; Fkhr1; forkhead box O1; forkhead box O1 a; forkhead box O1a; forkhead box O1A (rhabdomyosarcoma); forkhead box protein O1; forkhead box protein O1; LOW QUALITY PROTEIN: forkhead box protein O1; forkhead box protein O1A; Forkhead box protein O1-A; Forkhead in rhabdomyosarcoma; forkhead protein 1; forkhead protein FKHR; forkhead, Drosophila, homolog of, in rhabdomyosarcoma; fox family transcription factor FoxO1a.1; FOX01A; foxhead box protein O1-A; foxo1; FOXO1A; FoxO1a.1; member of FKHR-subclass forkhead/winged helix family; zgc:153388
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
2308, 56458, 84482
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
G3V7R4, Q12778, Q9R1E0
Gene Symbols
FOXO1
Immunogen
A synthesized peptide derived from human FOXO1(Accession Q12778), corresponding to amino acid residues around phosphorylated Ser249.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of FOXO1A only when phosphorylated at Ser249
- FOXO1 (FKHR, ForKHead Box 01) is a member in a subfamily of the forkhead homeotic gene family of transcription factors
- Recent experiments have shown that FOXO1 can act as either a coactivator or a corepressor of nuclear receptor activity that is mediated through the LXXLL motif found in the carboxyl terminal region of the FKHR protein
- Association of FOXO1 with PAX3 has been implicated in alveolar rhabdomyosarcoma
- Recent studies link the anti-tumor activity of FOXO1, the process of autophagy and myogenic growth and differentiation
- FOXO1 is the main target of insulin signaling that regulated the metabolic homeostasis in response to oxidative stress
- FOXO1 binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'- TT[G/A]TTTAC-3'
- FOXO1 is a regulator of redox balance, osteoblast numbers and controls bone mass
- Further, FOXO1 orchestrates the endocrine function of the skeleton in regulating glucose metabolism, and suppresses the transcriptional activity of RUNX2, an upstream activator of osteocalcin/BGLAP
- In hepatocytes, FOXO1 promotes gluconeogenesis by acting together with PPARGC1A to activate the expression of genes such as IGFBP1, G6PC and PPCK1
- FOXO1 is an important regulator of cell death acting downstream of CDK1, PKB/AKT1 and SKT4/MST1.
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Antigen: Phospho-FOXO1 (Ser249)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: FOXO1
Gene Alias: Afxh; AI876417; FKH1; FKHR; Fkhr1; forkhead box O1; forkhead box O1 a; forkhead box O1a; forkhead box O1A (rhabdomyosarcoma); forkhead box protein O1; forkhead box protein O1; LOW QUALITY PROTEIN: forkhead box protein O1; forkhead box protein O1A; Forkhead box protein O1-A; Forkhead in rhabdomyosarcoma; forkhead protein 1; forkhead protein FKHR; forkhead, Drosophila, homolog of, in rhabdomyosarcoma; fox family transcription factor FoxO1a.1; FOX01A; foxhead box protein O1-A; foxo1; FOXO1A; FoxO1a.1; member of FKHR-subclass forkhead/winged helix family; zgc:153388
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2308, 56458, 84482
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: G3V7R4, Q12778, Q9R1E0
Gene Symbols: FOXO1
Immunogen: A synthesized peptide derived from human FOXO1(Accession Q12778), corresponding to amino acid residues around phosphorylated Ser249.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-FOXO1 (Ser249)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
FOXO1
Gene Alias:
Afxh; AI876417; FKH1; FKHR; Fkhr1; forkhead box O1; forkhead box O1 a; forkhead box O1a; forkhead box O1A (rhabdomyosarcoma); forkhead box protein O1; forkhead box protein O1; LOW QUALITY PROTEIN: forkhead box protein O1; forkhead box protein O1A; Forkhead box protein O1-A; Forkhead in rhabdomyosarcoma; forkhead protein 1; forkhead protein FKHR; forkhead, Drosophila, homolog of, in rhabdomyosarcoma; fox family transcription factor FoxO1a.1; FOX01A; foxhead box protein O1-A; foxo1; FOXO1A; FoxO1a.1; member of FKHR-subclass forkhead/winged helix family; zgc:153388
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2308, 56458, 84482
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
G3V7R4, Q12778, Q9R1E0
Gene Symbols:
FOXO1
Immunogen:
A synthesized peptide derived from human FOXO1(Accession Q12778), corresponding to amino acid residues around phosphorylated Ser249.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-KIZUNA (Thr379)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: KIZ
Gene Alias: C20orf19; Centrosomal protein kizuna; Gm114; HT013; KIZ; Kizuna; kizuna centrosomal protein; NCRNA00153; PLK1S1; polo-like kinase 1 substrate 1; RGD1307071; RP69
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 55857
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q2M2Z5
Gene Symbols: KIZ
Immunogen: A synthesized peptide derived from human KIZ(Accession Q2M2Z5), corresponding to amino acid residues around phosphorylated Thr379.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-KIZUNA (Thr379)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
KIZ
Gene Alias:
C20orf19; Centrosomal protein kizuna; Gm114; HT013; KIZ; Kizuna; kizuna centrosomal protein; NCRNA00153; PLK1S1; polo-like kinase 1 substrate 1; RGD1307071; RP69
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
55857
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q2M2Z5
Gene Symbols:
KIZ
Immunogen:
A synthesized peptide derived from human KIZ(Accession Q2M2Z5), corresponding to amino acid residues around phosphorylated Thr379.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-NTAL (Tyr136)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: LAT2
Gene Alias: AW125574; HSPC046; LAB; Lat2; LAT-2 like; Linker for activation of B-cells; linker for activation of T cells family, member 2; linker for activation of T cells, transmembrane adaptor 2; linker for activation of T-cells family member 2; Membrane-associated adapter molecule; non-T cell activation linker; non-T-cell activation linker; NTAL; WBS15; WBSCR15; WBSCR5; Williams-Beuren syndrome chromosomal region 15 protein; williams-Beuren syndrome chromosomal region 15 protein homolog; Williams-Beuren syndrome chromosomal region 5 protein; Williams-Beuren syndrome chromosome region 5 homolog; Williams-Beuren syndrome chromosome region 5-like protein; WSCR5
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 317676, 56743, 7462
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q8CGL2, Q9GZY6, Q9JHL0
Gene Symbols: LAT2
Immunogen: A synthesized peptide derived from human LAT2(Accession Q9GZY6), corresponding to amino acid residues around phosphorylated Tyr136.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-NTAL (Tyr136)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
LAT2
Gene Alias:
AW125574; HSPC046; LAB; Lat2; LAT-2 like; Linker for activation of B-cells; linker for activation of T cells family, member 2; linker for activation of T cells, transmembrane adaptor 2; linker for activation of T-cells family member 2; Membrane-associated adapter molecule; non-T cell activation linker; non-T-cell activation linker; NTAL; WBS15; WBSCR15; WBSCR5; Williams-Beuren syndrome chromosomal region 15 protein; williams-Beuren syndrome chromosomal region 15 protein homolog; Williams-Beuren syndrome chromosomal region 5 protein; Williams-Beuren syndrome chromosome region 5 homolog; Williams-Beuren syndrome chromosome region 5-like protein; WSCR5
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
317676, 56743, 7462
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q8CGL2, Q9GZY6, Q9JHL0
Gene Symbols:
LAT2
Immunogen:
A synthesized peptide derived from human LAT2(Accession Q9GZY6), corresponding to amino acid residues around phosphorylated Tyr136.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-MAP2 (Ser136)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Map2
Gene Alias: a730034c02; AC091465.1; DKFZp686I2148; G1-397-34; MAP 2; Map2; MAP-2; map2.S; map2a; map-2a; map2ab; MAP2B; MAP2C; MAP2R; microtubule associated protein 2; microtubule associated protein 2 S homeolog; microtubule associated protein 2; microtubule-associated protein 2; microtubule associated protein 2C; microtubule-associated protein 2; microtubule-associated protein-2; Mtap2; Mtap-2; OTTHUMP00000163916; OTTHUMP00000208143; repro4; XELAEV_18047318mg; xmap2
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17756, 25595, 4133
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P11137, P15146, P20357
Gene Symbols: Map2
Immunogen: A synthesized peptide derived from human MAP2(Accession P11137), corresponding to amino acid residues around phosphorylated Ser136.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-MAP2 (Ser136)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Map2
Gene Alias:
a730034c02; AC091465.1; DKFZp686I2148; G1-397-34; MAP 2; Map2; MAP-2; map2.S; map2a; map-2a; map2ab; MAP2B; MAP2C; MAP2R; microtubule associated protein 2; microtubule associated protein 2 S homeolog; microtubule associated protein 2; microtubule-associated protein 2; microtubule associated protein 2C; microtubule-associated protein 2; microtubule-associated protein-2; Mtap2; Mtap-2; OTTHUMP00000163916; OTTHUMP00000208143; repro4; XELAEV_18047318mg; xmap2
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17756, 25595, 4133
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P11137, P15146, P20357
Gene Symbols:
Map2
Immunogen:
A synthesized peptide derived from human MAP2(Accession P11137), corresponding to amino acid residues around phosphorylated Ser136.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG