PIPA5106095
Phospho-ITGB1 (Tyr783) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5106095-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5106095 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
Phospho-ITGB1 (Tyr783)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ITGB1
Gene Alias
4633401G24Rik; AA409975; AA960159; Beta OL; beta oligodendroglia; CD29; CSAT antigen; ENSMUSG00000051907; Fibronectin receptor subunit beta; FNRB; Glycoprotein IIa; Gm9863; gpIIa; integrin beta 1; integrin beta 1 (fibronectin receptor beta); integrin beta 1A precursor; Integrin beta1; integrin beta-1; integrin beta-1 subunit; integrin beta1D; integrin precursor; integrin subunit beta 1; integrin VLA-4 beta subunit; integrin VLA-4 subunit beta; integrin, beta 1; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); ITBG1D; ITGB1; JG22 antigen; MDF2; MSK12; RGD-receptor; very late activation protein, beta polypeptide; VLA-4 subunit beta; VLAB; VLA-BETA
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
16412, 24511, 3688
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P05556, P09055, P49134
Gene Symbols
ITGB1
Immunogen
A synthesized peptide derived from human ITGB1(Accession P05556), corresponding to amino acid residues around phosphorylated Tyr783.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of Integrin beta 1 only when phosphorylated at Tyr783
- ITGB1 (Integrin Subunit Beta 1, beta1 integrin subunit, GPIIa, CD29) is a 110 kDa cell surface glycoprotein that is widely expressed by a variety of cells including all leucocytes
- ITGB1 forms non-covalently linked heterodimers with at least 6 different alpha chains (alpha1-alpha6, CDa-f) determining the binding properties of beta1 (VLA) integrins
- ITGB1 is a cell adhesion molecule appearing on platelets, as the common Beta subunit of the very late activation antigen (VLA), and as a component of various protein complexes binding to extracellular matrix proteins
- Decreased expression of ITGB1 correlates with acquiring multidrug resistance of tumor cells in the presence of anti-tumor drug
- ITGB1 is up-regulated in leukocytes during emigration and extravascular migration and appear to be critically involved in regulating the immune cell trafficking from blood to tissue
- Further, ITGB1 also regulates tissue damage and disease symptoms related to inflammatory bowel disease
- Through an ITGB1-dependent mechanism, fibronectin and type I collagen enhance cytokine secretion of human airway smooth muscle in response to IL-1beta
- More than 8 beta subunits with numerous splice variant isoforms have been identified in mammals
- There are two major forms of integrin beta1: beta1A and beta1D, which differ in 13 amino acids
- The distribution pattern in adult tissues for integrin beta types are mutually exclusive
- Beta1A is present in all tissues, except cardiac and skeletal muscle which express the beta1D variant.
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Antigen: Phospho-ITGB1 (Tyr783)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ITGB1
Gene Alias: 4633401G24Rik; AA409975; AA960159; Beta OL; beta oligodendroglia; CD29; CSAT antigen; ENSMUSG00000051907; Fibronectin receptor subunit beta; FNRB; Glycoprotein IIa; Gm9863; gpIIa; integrin beta 1; integrin beta 1 (fibronectin receptor beta); integrin beta 1A precursor; Integrin beta1; integrin beta-1; integrin beta-1 subunit; integrin beta1D; integrin precursor; integrin subunit beta 1; integrin VLA-4 beta subunit; integrin VLA-4 subunit beta; integrin, beta 1; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); ITBG1D; ITGB1; JG22 antigen; MDF2; MSK12; RGD-receptor; very late activation protein, beta polypeptide; VLA-4 subunit beta; VLAB; VLA-BETA
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16412, 24511, 3688
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P05556, P09055, P49134
Gene Symbols: ITGB1
Immunogen: A synthesized peptide derived from human ITGB1(Accession P05556), corresponding to amino acid residues around phosphorylated Tyr783.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-ITGB1 (Tyr783)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ITGB1
Gene Alias:
4633401G24Rik; AA409975; AA960159; Beta OL; beta oligodendroglia; CD29; CSAT antigen; ENSMUSG00000051907; Fibronectin receptor subunit beta; FNRB; Glycoprotein IIa; Gm9863; gpIIa; integrin beta 1; integrin beta 1 (fibronectin receptor beta); integrin beta 1A precursor; Integrin beta1; integrin beta-1; integrin beta-1 subunit; integrin beta1D; integrin precursor; integrin subunit beta 1; integrin VLA-4 beta subunit; integrin VLA-4 subunit beta; integrin, beta 1; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); ITBG1D; ITGB1; JG22 antigen; MDF2; MSK12; RGD-receptor; very late activation protein, beta polypeptide; VLA-4 subunit beta; VLAB; VLA-BETA
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16412, 24511, 3688
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P05556, P09055, P49134
Gene Symbols:
ITGB1
Immunogen:
A synthesized peptide derived from human ITGB1(Accession P05556), corresponding to amino acid residues around phosphorylated Tyr783.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-Mdm2 (Tyr394)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MDM2
Gene Alias: 1700007J15Rik; AA415488; ACTFS; double minute 2; double minute 2 protein; double minute 2, human homolog of; p53-binding protein; E3 ubiquitin-protein ligase Mdm2; Hdm2; HDMX; HGNC:6973; human homolog of; MDM2; Mdm-2; MDM2 oncogene, E3 ubiquitin protein ligase; Mdm2 p53 binding protein homolog; MDM2 proto-oncogene; MDM2 proto-oncogene, E3 ubiquitin protein ligase; MDM2 variant FB28; Mdm2, p53 E3 ubiquitin protein ligase homolog; Mdm2, transformed 3T3 cell double minute 2, p53 binding protein; MGC5370; MGC71221; oncoprotein Mdm2; OTTHUMP00000183490; OTTHUMP00000183492; OTTHUMP00000183494; OTTHUMP00000183495; OTTHUMP00000183496; OTTHUMP00000183497; p53 E3 ubiquitin protein ligase; p53-binding protein Mdm2; RING-type E3 ubiquitin transferase Mdm2; transformed mouse 3T3 cell double minute 2
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17246, 4193
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P23804, Q00987
Gene Symbols: MDM2
Immunogen: A synthesized peptide derived from human MDM2(Accession Q00987), corresponding to amino acid residues around phosphorylated Tyr394.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-Mdm2 (Tyr394)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MDM2
Gene Alias:
1700007J15Rik; AA415488; ACTFS; double minute 2; double minute 2 protein; double minute 2, human homolog of; p53-binding protein; E3 ubiquitin-protein ligase Mdm2; Hdm2; HDMX; HGNC:6973; human homolog of; MDM2; Mdm-2; MDM2 oncogene, E3 ubiquitin protein ligase; Mdm2 p53 binding protein homolog; MDM2 proto-oncogene; MDM2 proto-oncogene, E3 ubiquitin protein ligase; MDM2 variant FB28; Mdm2, p53 E3 ubiquitin protein ligase homolog; Mdm2, transformed 3T3 cell double minute 2, p53 binding protein; MGC5370; MGC71221; oncoprotein Mdm2; OTTHUMP00000183490; OTTHUMP00000183492; OTTHUMP00000183494; OTTHUMP00000183495; OTTHUMP00000183496; OTTHUMP00000183497; p53 E3 ubiquitin protein ligase; p53-binding protein Mdm2; RING-type E3 ubiquitin transferase Mdm2; transformed mouse 3T3 cell double minute 2
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17246, 4193
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P23804, Q00987
Gene Symbols:
MDM2
Immunogen:
A synthesized peptide derived from human MDM2(Accession Q00987), corresponding to amino acid residues around phosphorylated Tyr394.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-MYLK (Tyr471)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MYLK
Gene Alias: 155 kda myosin light chain kinase homolog; 9530072E15Rik; A clone isolated from a chicken gizzard cDNA library which has high homology with the 3'-end sequence of the chicken gizzard myosin light chain kinase (MLCK) cDNA; The 5'-leader seqeuence derives from the intronic sequence of the MLCK gene.; A930019C19Rik; AAT7; AW489456; kinase related protein; kinase-related protein; KRP; KRP/Telokin; MLCK; MLCK1; MLCK108; MLCK210; MSTP083; mylk; MYLK1; myosin light chain kinase; myosin light chain kinase, smooth muscle; Myosin light chain kinase, smooth muscle, deglutamylated form; myosin, light polypeptide kinase; nmMlck; smMLCK; smooth muscle myosin light chain kinase; smooth muscle myosin light chain kinase (61-kDa active fragment); smooth muscle myosin light chain kinase precursor (EC 2.7.2.37); telokin; unnamed protein product
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4638
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q15746
Gene Symbols: MYLK
Immunogen: A synthesized peptide derived from human MYLK(Accession Q15746), corresponding to amino acid residues around phosphorylated Tyr471.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-MYLK (Tyr471)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MYLK
Gene Alias:
155 kda myosin light chain kinase homolog; 9530072E15Rik; A clone isolated from a chicken gizzard cDNA library which has high homology with the 3'-end sequence of the chicken gizzard myosin light chain kinase (MLCK) cDNA; The 5'-leader seqeuence derives from the intronic sequence of the MLCK gene.; A930019C19Rik; AAT7; AW489456; kinase related protein; kinase-related protein; KRP; KRP/Telokin; MLCK; MLCK1; MLCK108; MLCK210; MSTP083; mylk; MYLK1; myosin light chain kinase; myosin light chain kinase, smooth muscle; Myosin light chain kinase, smooth muscle, deglutamylated form; myosin, light polypeptide kinase; nmMlck; smMLCK; smooth muscle myosin light chain kinase; smooth muscle myosin light chain kinase (61-kDa active fragment); smooth muscle myosin light chain kinase precursor (EC 2.7.2.37); telokin; unnamed protein product
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4638
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q15746
Gene Symbols:
MYLK
Immunogen:
A synthesized peptide derived from human MYLK(Accession Q15746), corresponding to amino acid residues around phosphorylated Tyr471.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-PLCG1 (Ser1248)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PLCG1
Gene Alias: 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1; AI894140; Cded; cell differentiation and embryonic development; EC 3.1.4.11; inositoltrisphosphohydrolase; monophosphatidylinositol phosphodiesterase; NCKAP3; OTTHUMP00000178982; phosphatidylinositol phospholipase C; phosphoinositidase C; phosphoinositide phospholipase C; phosphoinositide phospholipase C-gamma-1; phospholipase C gamma 1; phospholipase C, gamma 1; phospholipase C, gamma 1 (formerly subtype 148); phospholipase C-1; phospholipase C-148; Phospholipase C2; phospholipase C-gamma-1; Phospholipase C-II; PLC gamma1; PLC1; Plc-1; PLC148; PLC-148; PLC2I; Plcg1; Plcg-1; PLCgamma1; Plc-gamma1; PLC-gamma-1; PLC-II; PPLCA; triphosphoinositide phosphodiesterase
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18803, 25738, 5335
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P10686, P19174, Q62077
Gene Symbols: PLCG1
Immunogen: A synthesized peptide derived from human PLCG1(Accession P19174), corresponding to amino acid residues around phosphorylated Ser1248.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-PLCG1 (Ser1248)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PLCG1
Gene Alias:
1-phosphatidyl-D-myo-inositol-4,5-bisphosphate; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1; AI894140; Cded; cell differentiation and embryonic development; EC 3.1.4.11; inositoltrisphosphohydrolase; monophosphatidylinositol phosphodiesterase; NCKAP3; OTTHUMP00000178982; phosphatidylinositol phospholipase C; phosphoinositidase C; phosphoinositide phospholipase C; phosphoinositide phospholipase C-gamma-1; phospholipase C gamma 1; phospholipase C, gamma 1; phospholipase C, gamma 1 (formerly subtype 148); phospholipase C-1; phospholipase C-148; Phospholipase C2; phospholipase C-gamma-1; Phospholipase C-II; PLC gamma1; PLC1; Plc-1; PLC148; PLC-148; PLC2I; Plcg1; Plcg-1; PLCgamma1; Plc-gamma1; PLC-gamma-1; PLC-II; PPLCA; triphosphoinositide phosphodiesterase
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18803, 25738, 5335
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P10686, P19174, Q62077
Gene Symbols:
PLCG1
Immunogen:
A synthesized peptide derived from human PLCG1(Accession P19174), corresponding to amino acid residues around phosphorylated Ser1248.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG