PIPA5106261
PDE6 gamma Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5106261-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5106261 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
PDE6 gamma
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PDE6G
Gene Alias
GMP-PDE gamma; p3AT; PDE6G; PDEG; phosphodiesterase 6G; phosphodiesterase 6G, cGMP-specific, rod, gamma; phosphodiesterase, cyclic GMP (rod receptor), gamma polypeptide; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma; rod cG-PDE G; RP57; unnamed protein product
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
18588, 5148, 688297
Content And Storage
-20°C
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P09174, P18545
Gene Symbols
PDE6G
Immunogen
A synthesized peptide derived from human PDE6G(Accession P18545), corresponding to amino acid residues M1-F50.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total PDE6G
- The second messengers cAMP and cGMP are key regulatory molecules that are involved in a wide variety of signal transduction pathways
- Levels of cAMP and cGMP are regulated by their rate of synthesis by nucleotide cyclases and by their rate of hydrolysis by cyclic nucleotide phosphodiesterases (PDEs)
- PDEs form a superfamily of enzymes that catalyze the conversion of 3-prime, 5-prime-cyclic nucleotides to the corresponding nucleoside 5-prime-monophosphates
- PDE6 is the effector enzyme in the G protein-mediated signal transduction cascade in the visual system
- There are five different subunits consisting of rod and cone specific catalytic subunits: alpha' (Cone), alpha (Rod), and beta (Rod), the inhibitory subunit gamma, and subunit delta of unknown function (which likely interacts with many other proteins besides the PDE6 family)
- The catalytic core of the PDE6 system is comprised of alpha'/alpha' homodimers in the cone and alpha/beta heterodimers in the rod
- The C-terminus of both the catalytic and inhibitory subunits is modified by methylation, myristyolation and prenylation which have been shown to be critical for proper complex assembly and membrane association.
Compare Similar Items
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Antigen: PDE6 gamma
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PDE6G
Gene Alias: GMP-PDE gamma; p3AT; PDE6G; PDEG; phosphodiesterase 6G; phosphodiesterase 6G, cGMP-specific, rod, gamma; phosphodiesterase, cyclic GMP (rod receptor), gamma polypeptide; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma; rod cG-PDE G; RP57; unnamed protein product
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18588, 5148, 688297
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P09174, P18545
Gene Symbols: PDE6G
Immunogen: A synthesized peptide derived from human PDE6G(Accession P18545), corresponding to amino acid residues M1-F50.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PDE6 gamma
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PDE6G
Gene Alias:
GMP-PDE gamma; p3AT; PDE6G; PDEG; phosphodiesterase 6G; phosphodiesterase 6G, cGMP-specific, rod, gamma; phosphodiesterase, cyclic GMP (rod receptor), gamma polypeptide; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma; rod cG-PDE G; RP57; unnamed protein product
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18588, 5148, 688297
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P09174, P18545
Gene Symbols:
PDE6G
Immunogen:
A synthesized peptide derived from human PDE6G(Accession P18545), corresponding to amino acid residues M1-F50.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: PRK1/PRK2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PKN2
Gene Alias: 6030436C20Rik; AI507382; cardiolipin-activated protein kinase Pak2; DBK; F730027O18Rik; p140 kinase; PAK1; PAK-1; PAK2; Pak-2; Pkn; PKN gamma; Pkn1; Pkn2; PKN-ALPHA; Prk1; Prk2; Prkcl1; PRKCL2; PRO2042; protease-activated kinase 1; protease-activated kinase 2; protein kinase C-like 1; Protein kinase C-like 2; protein kinase C-like PKN; protein kinase C-related kinase 1; protein kinase N1; protein kinase N2; protein kinase PKN; protein kinase PKN-alpha; Protein-kinase C-related kinase 1; protein-kinase C-related kinase 2; serine/threonine kinase 3; serine/threonine kinase 7; serine/threonine protein kinase N; serine/threonine-protein kinase N1; Serine/threonine-protein kinase N2; serine-threonine kinase N; serine-threonine protein kinase N; Stk3; Stk7
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 109333, 207122, 29355, 320795, 5585, 5586
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: O08874, P70268, Q16512, Q16513, Q63433, Q8BWW9
Gene Symbols: PKN1, PKN2
Immunogen: A synthesized peptide derived from human PKN1(Accession Q16512), corresponding to amino acid residues L748-W798.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PRK1/PRK2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PKN2
Gene Alias:
6030436C20Rik; AI507382; cardiolipin-activated protein kinase Pak2; DBK; F730027O18Rik; p140 kinase; PAK1; PAK-1; PAK2; Pak-2; Pkn; PKN gamma; Pkn1; Pkn2; PKN-ALPHA; Prk1; Prk2; Prkcl1; PRKCL2; PRO2042; protease-activated kinase 1; protease-activated kinase 2; protein kinase C-like 1; Protein kinase C-like 2; protein kinase C-like PKN; protein kinase C-related kinase 1; protein kinase N1; protein kinase N2; protein kinase PKN; protein kinase PKN-alpha; Protein-kinase C-related kinase 1; protein-kinase C-related kinase 2; serine/threonine kinase 3; serine/threonine kinase 7; serine/threonine protein kinase N; serine/threonine-protein kinase N1; Serine/threonine-protein kinase N2; serine-threonine kinase N; serine-threonine protein kinase N; Stk3; Stk7
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
109333, 207122, 29355, 320795, 5585, 5586
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
O08874, P70268, Q16512, Q16513, Q63433, Q8BWW9
Gene Symbols:
PKN1, PKN2
Immunogen:
A synthesized peptide derived from human PKN1(Accession Q16512), corresponding to amino acid residues L748-W798.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: MERTK
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Mertk
Gene Alias: c-Eyk; c-mer; c-mer proto-oncogene tyrosine kinase; Eyk; MER; MER proto-oncogene, tyrosine kinase; MER receptor tyrosine kinase; MERTK; MGC133349; nmf12; Nyk; Proto-oncogene c-Mer; proto-oncogene tyrosine-protein kinase MER; rdy; receptor tyrosine kinase MerTK; Receptor tyrosine tinase gene probably the gene for Rdy; retinal dystrophy; RP38; sMER; sMERTK; soluble MER; soluble MERTK; STK kinase; Tyro 12; Tyro12; Tyrosine-protein kinase Mer
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10461, 17289
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q12866, Q60805
Gene Symbols: Mertk
Immunogen: A synthesized peptide derived from human MERTK(Accession Q12866), corresponding to amino acid residues R727-Y777.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
MERTK
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Mertk
Gene Alias:
c-Eyk; c-mer; c-mer proto-oncogene tyrosine kinase; Eyk; MER; MER proto-oncogene, tyrosine kinase; MER receptor tyrosine kinase; MERTK; MGC133349; nmf12; Nyk; Proto-oncogene c-Mer; proto-oncogene tyrosine-protein kinase MER; rdy; receptor tyrosine kinase MerTK; Receptor tyrosine tinase gene probably the gene for Rdy; retinal dystrophy; RP38; sMER; sMERTK; soluble MER; soluble MERTK; STK kinase; Tyro 12; Tyro12; Tyrosine-protein kinase Mer
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10461, 17289
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q12866, Q60805
Gene Symbols:
Mertk
Immunogen:
A synthesized peptide derived from human MERTK(Accession Q12866), corresponding to amino acid residues R727-Y777.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: TOPBP1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TOPBP1
Gene Alias: 1110031N14Rik; 2810429C13Rik; AI256758; D430026L04Rik; DNA topoisomerase 2-binding protein 1; DNA topoisomerase II-beta-binding protein 1; DNA topoisomerase II-binding protein 1; KIAA0259; mKIAA0259; RGD1562949; TOP2BP1; TOPBP 1; Topbp1; topoisomerase (DNA) II beta binding protein; topoisomerase (DNA) II binding protein 1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11073, 235559
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q6ZQF0, Q92547
Gene Symbols: TOPBP1
Immunogen: A synthesized peptide derived from human TOPBP1(Accession Q92547), corresponding to amino acid residues V1133-S1183.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
TOPBP1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TOPBP1
Gene Alias:
1110031N14Rik; 2810429C13Rik; AI256758; D430026L04Rik; DNA topoisomerase 2-binding protein 1; DNA topoisomerase II-beta-binding protein 1; DNA topoisomerase II-binding protein 1; KIAA0259; mKIAA0259; RGD1562949; TOP2BP1; TOPBP 1; Topbp1; topoisomerase (DNA) II beta binding protein; topoisomerase (DNA) II binding protein 1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11073, 235559
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q6ZQF0, Q92547
Gene Symbols:
TOPBP1
Immunogen:
A synthesized peptide derived from human TOPBP1(Accession Q92547), corresponding to amino acid residues V1133-S1183.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG