PIPA5106291

COMMD1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5106291-Each-of-1 In Stock ₹ 44,705.10

PIPA5106291 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

COMMD1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

COMMD1

Gene Alias

AI256843; C2orf5; COMM domain containing 1; COMM domain-containing protein 1; Commd1; copper metabolism (Murr1) domain containing 1; copper metabolism domain containing 1; copper metabolism gene MURR1; Murr1; Protein Murr1; U2/Mu; U2af1-rs1 region 1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

150684, 17846, 289831

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q8K4M5, Q8N668

Gene Symbols

COMMD1

Immunogen

A synthesized peptide derived from human COMMD1(Accession Q8N668), corresponding to amino acid residues S100-G150.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total COMMD1
  • Proposed scaffold protein that is implicated in diverse physiological processes and whose function may be in part linked to its ability to regulate ubiquitination of specific cellular proteins
  • Can modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes by displacing CAND1; in vitro promotes CRL E3 activiy and dissocoiates CAND1 from CUL1 and CUL2
  • Promotes ubiquitination of NF-kappa-B subunit RELA and its subsequent proteasomal degradation
  • Down-regulates NF-kappa-B activity
  • Involved in the regulation of membrane expression and ubiquitination of SLC12A2
  • Modulates Na(+) transport in epithelial cells by regulation of apical cell surface expression of amiloride-sensitive sodium channel (ENaC) subunits and by promoting their ubiquitination presumably involving NEDD4L
  • Promotes the localization of SCNN1D to recycling endosomes
  • Promotes CFTR cell surface expression through regulation of its ubiquitination
  • Down-regulates SOD1 activity by interfering with its homodimerization
  • Plays a role in copper ion homeostasis
  • Involved in copper-dependent ATP7A trafficking between the trans- Golgi network and vesicles in the cell periphery; the function is proposed to depend on its association within the CCC complex and cooperation with the WASH complex on early endosomes
  • Can bind one copper ion per monomer
  • May function to facilitate biliary copper excretion within hepatocytes
  • Binds to phosphatidylinositol 4,5- bisphosphate (PtdIns(4,5)P2)
  • Involved in the regulation of HIF1A-mediated transcription; competes with ARNT/Hif-1-beta for binding to HIF1A resulting in decreased DNA binding and impaired transcriptional activation by HIF-1.

Compare Similar Items

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Img

Thermo Scientific

PIPA5106291

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Antigen:
COMMD1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
COMMD1

Gene Alias:
AI256843; C2orf5; COMM domain containing 1; COMM domain-containing protein 1; Commd1; copper metabolism (Murr1) domain containing 1; copper metabolism domain containing 1; copper metabolism gene MURR1; Murr1; Protein Murr1; U2/Mu; U2af1-rs1 region 1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
150684, 17846, 289831

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q8K4M5, Q8N668

Gene Symbols:
COMMD1

Immunogen:
A synthesized peptide derived from human COMMD1(Accession Q8N668), corresponding to amino acid residues S100-G150.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5106292

--


Antigen:
DHRS3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Dhrs3

Gene Alias:
DD83.1; dehydrogenase/reductase (SDR family) member 3; dehydrogenase/reductase 3; dehydrogenase/reductase member 3; Dhrs3; RDH17; retinal dehydrogenase/reductase family member 3; retinal short-chain dehydrogenase/reductase 1; Retinol dehydrogenase 17; retSDR1; Rsdr1; SDR1; SDR16C1; Short chain dehydrogenase/reductase family 16C member 1; short chain dehydrogenase/reductase family 16C, member 1; short-chain dehydrogenase/reductase 1; short-chain dehydrogenase/reductase 3; UNQ2424/PRO4983

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20148, 313689, 9249

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O75911, O88876

Gene Symbols:
Dhrs3

Immunogen:
A synthesized peptide derived from human DHRS3(Accession O75911), corresponding to amino acid residues A59-A109.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5106293

--


Antigen:
FKBP10

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FKBP10

Gene Alias:
65 kDa FK506-binding protein; 65 kDa FKBP; AI325255; BRKS1; FK506 binding protein 10; FK506 binding protein 10, 65 kDa; FK506 binding protein 6 (65 kDa); FK506-binding protein 10; FKBP10; FKBP-10; Fkbp1-rs; Fkbp6; FKBP65; FKBP-65; Fkbprp; Fkbp-rs; Fkbp-rs1; hFKBP65; Immunophilin FKBP65; OI11; OI6; Peptidyl-prolyl cis-trans isomerase FKBP10; PPIASE; PPIase FKBP10; PSEC0056; Rotamase

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14230, 360627, 60681

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q61576, Q96AY3

Gene Symbols:
FKBP10

Immunogen:
A synthesized peptide derived from human FKBP10(Accession Q96AY3), corresponding to amino acid residues L218-V268.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5106294

--


Antigen:
IST1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IST1

Gene Alias:
2400003C14Rik; AW536298; fb16b04; hIST1; hypothetical protein LOC321460; hypothetical protein LOC508900; increased sodium tolerance 1 homolog; increased sodium tolerance 1 homolog (yeast); IST1; IST1 factor associated with ESCRT-III; IST1 homolog; IST1, endosomal sorting complex required for transport-III component; IST1, ESCRT-III associated factor; IST1-like protein; Kiaa0174; KIAA0174-like protein; MAPK activating protein PM28; MGC117220; mKIAA0174; OLC1; overexpressed in lung cancer 1; pm28; putative MAPK-activating protein PM28; RGD1307799; wu:fb16b04; wu:fi89e07; zgc:55671

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
71955, 9798

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P53990, Q9CX00

Gene Symbols:
IST1

Immunogen:
A synthesized peptide derived from human IST1(Accession P53990), corresponding to amino acid residues P246-Q296.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG