PIPA5106333

OTUD7B Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5106333-Each-of-1 In Stock ₹ 44,705.10

PIPA5106333 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

OTUD7B

Classification

Polyclonal

Conjugate

Unconjugated

Gene

OTUD7B

Gene Alias

2900060B22Rik; 4930463P07Rik; AI462125; cellular zinc finger anti-NF-kappaB Cezanne; cellular zinc finger anti-NF-kappa-B protein; CEZANNE; OTU deubiquitinase 7B; OTU domain containing 7B; OTU domain-containing protein 7B; OTUD7B; RGD1308111; Trabid2; TRAF binding domain containing 2; Za20d1; Zinc finger A20 domain-containing protein 1; zinc finger protein Cezanne; zinc finger, A20 domain containing 1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

229603, 310677, 56957

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

B2RUR8, Q6GQQ9

Gene Symbols

OTUD7B

Immunogen

A synthesized peptide derived from human OTUD7B(Accession Q6GQQ9), corresponding to amino acid residues D757-C807.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA5102686

--

Img

Thermo Scientific

PIPA5104924

--

Img

Thermo Scientific

PA551031

--

Img

Thermo Scientific

PIPA5104678

--

Img

Thermo Scientific

PIPA5104754

--

Img

Thermo Scientific

PIPA5105492

--

Img

Thermo Scientific

PIPA5104986

--

Img

Thermo Scientific

PIPA5114645

--

Description

  • Antibody detects endogenous levels of total OTUD7B
  • Negative regulator of the non-canonical NF-kappa-B pathway that acts by mediating deubiquitination of TRAF3, an inhibitor of the NF-kappa-B pathway, thereby acting as a negative regulator of B-cell responses
  • In response to non-canonical NF-kappa-B stimuli, deubiquitinates 'Lys-48'-linked polyubiquitin chains of TRAF3, preventing TRAF3 proteolysis and over-activation of non-canonical NF-kappa-B
  • Negatively regulates mucosal immunity against infections
  • Deubiquitinates ZAP70, and thereby regulates T cell receptor (TCR) signaling that leads to the activation of NF-kappa-B (PubMed:26903241)
  • Plays a role in T cell homeostasis and is required for normal T cell responses, including production of IFNG and IL2
  • Mediates deubiquitination of EGFR (PubMed:22179831)
  • Has deubiquitinating activity toward 'Lys-11', 'Lys-48' and 'Lys-63'-linked polyubiquitin chains (PubMed:27732584)
  • Has a much higher catalytic rate with 'Lys-11'-linked polyubiquitin chains (in vitro); however the physiological significance of these data are unsure (PubMed:27732584)
  • Hydrolyzes both linear and branched forms of polyubiquitin
  • [UniProt]

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5106333

--


Antigen:
OTUD7B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
OTUD7B

Gene Alias:
2900060B22Rik; 4930463P07Rik; AI462125; cellular zinc finger anti-NF-kappaB Cezanne; cellular zinc finger anti-NF-kappa-B protein; CEZANNE; OTU deubiquitinase 7B; OTU domain containing 7B; OTU domain-containing protein 7B; OTUD7B; RGD1308111; Trabid2; TRAF binding domain containing 2; Za20d1; Zinc finger A20 domain-containing protein 1; zinc finger protein Cezanne; zinc finger, A20 domain containing 1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
229603, 310677, 56957

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
B2RUR8, Q6GQQ9

Gene Symbols:
OTUD7B

Immunogen:
A synthesized peptide derived from human OTUD7B(Accession Q6GQQ9), corresponding to amino acid residues D757-C807.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5106334

--


Antigen:
P4HA1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
P4HA1

Gene Alias:
4-PH alpha-1; AL022634; collagen prolyl 4-hydroxylase alpha(I); C-P4Halpha(I); P4ha; P4ha1; PHalphaI; procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide; procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide I; procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1; prolyl 4-hydroxylase alpha subunit; prolyl 4-hydroxylase subunit alpha 1; prolyl 4-hydroxylase subunit alpha-1; prolyl 4-hydroxylase, alpha polypeptide I

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18451, 5033, 64475

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P13674, P54001, Q60715

Gene Symbols:
P4HA1

Immunogen:
A synthesized peptide derived from human P4HA1(Accession P13674), corresponding to amino acid residues K52-V102.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5106335

--


Antigen:
PNAS4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DESI2

Gene Alias:
5830417C01Rik; C1orf121; cb238; CGI-146; DESI; DESI1; desi2; DeSI-2; desumoylating isopeptidase 1; desumoylating isopeptidase 2; Deubiquitinase DESI2; Fam152a; family with sequence similarity 152, member A; fi12d12; hypothetical protein LOC445138; pnas4; PNAS-4; PPPDE peptidase domain containing 1; PPPDE peptidase domain-containing protein 1; Pppde1; Protein FAM152A; sb:cb238; si:ch211-132e22.3; wu:fi12d12; zgc:100860

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
289277, 51029, 78825

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q5XIT6, Q9BSY9, Q9D291

Gene Symbols:
DESI2

Immunogen:
A synthesized peptide derived from human DESI2(Accession Q9BSY9), corresponding to amino acid residues T21-E71.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5106336

--


Antigen:
PRPH2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PRPH2

Gene Alias:
AOFMD; AVMD; CACD2; DS; MDBS1; Nmf193; peripherin 2; peripherin 2 (retinal degeneration, slow); peripherin 2, homolog of mouse; peripherin, photoreceptor type; peripherin-2; PRPH; PRPH2; Rd2; Rd-2; RDS; retinal degeneration 2; retinal degeneration slow protein; retinal degeneration, slow; retinal degeneration, slow (retinitis pigmentosa 7); retinal peripherin; RP7; RSRDS; tetraspanin-22; TSPAN22; Tspan-22

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19133, 25534, 5961

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P15499, P17438, P23942

Gene Symbols:
PRPH2

Immunogen:
A synthesized peptide derived from human PRPH2(Accession P23942), corresponding to amino acid residues P147-K197.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG