PIPA5106340
SHOC2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5106340-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5106340 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
SHOC2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Shoc2
Gene Alias
AU017287; KIAA0862; Leucine-rich repeat protein SHOC-2; mKIAA0862; Protein soc-2 homolog; protein sur-8 homolog; Ras-binding protein SUR-8; RP11-348N5.2; Shoc2; SHOC2 leucine-rich repeat scaffold protein; SHOC2, leucine rich repeat scaffold protein; SIAA0862; SOC2; soc-2 (suppressor of clear) homolog; soc-2 (suppressor of clear) homolog (C. elegans); soc-2 suppressor of clear homolog; soc-2 suppressor of clear homolog (C. elegans); suppressor of clear, C. elegans, homolog of; SUR8
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
309548, 56392, 8036
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
O88520, Q6AYI5, Q9UQ13
Gene Symbols
Shoc2
Immunogen
A synthesized peptide derived from human SHOC2(Accession Q9UQ13), corresponding to amino acid residues S532-V582.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total Sur-8
- SHOC2 protein participates in protein binding / transferase activity in the fibroblast growth factor receptor signaling pathway and Ras protein signal transduction
- It is a widely expressed protein composed almost entirely of leucine-rich repeats (LRR), with a lysine-rich sequence at the amino terminus and cytoplasmically localized
- SHOC2 acts as a positive modulator of the RAS-MAPK signaling cascade, which is elicited by EGL-15 and LET-23 and mediated by LET-60
- SHOC2 together with protein phosphatase 1c (PP1c) forms a highly specific M-Ras effector complex and is essential for activation of the MAPK pathway by growth factors
- Furthermore, in tumor cells with Ras gene mutations, inhibition of SHOC2 expression inhibits MAPK, but not PI3K activity
- The SHOC2-PP1c holoenzyme provides an attractive therapeutic target for inhibition of the MAPK pathway in cancer
- Recent studies show that aberrantly acquired N-myristoylation of SHOC2 causes human disease Noonan-like syndrome with loose anagen hair.
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Antigen: SHOC2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Shoc2
Gene Alias: AU017287; KIAA0862; Leucine-rich repeat protein SHOC-2; mKIAA0862; Protein soc-2 homolog; protein sur-8 homolog; Ras-binding protein SUR-8; RP11-348N5.2; Shoc2; SHOC2 leucine-rich repeat scaffold protein; SHOC2, leucine rich repeat scaffold protein; SIAA0862; SOC2; soc-2 (suppressor of clear) homolog; soc-2 (suppressor of clear) homolog (C. elegans); soc-2 suppressor of clear homolog; soc-2 suppressor of clear homolog (C. elegans); suppressor of clear, C. elegans, homolog of; SUR8
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 309548, 56392, 8036
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: O88520, Q6AYI5, Q9UQ13
Gene Symbols: Shoc2
Immunogen: A synthesized peptide derived from human SHOC2(Accession Q9UQ13), corresponding to amino acid residues S532-V582.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
SHOC2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Shoc2
Gene Alias:
AU017287; KIAA0862; Leucine-rich repeat protein SHOC-2; mKIAA0862; Protein soc-2 homolog; protein sur-8 homolog; Ras-binding protein SUR-8; RP11-348N5.2; Shoc2; SHOC2 leucine-rich repeat scaffold protein; SHOC2, leucine rich repeat scaffold protein; SIAA0862; SOC2; soc-2 (suppressor of clear) homolog; soc-2 (suppressor of clear) homolog (C. elegans); soc-2 suppressor of clear homolog; soc-2 suppressor of clear homolog (C. elegans); suppressor of clear, C. elegans, homolog of; SUR8
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
309548, 56392, 8036
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
O88520, Q6AYI5, Q9UQ13
Gene Symbols:
Shoc2
Immunogen:
A synthesized peptide derived from human SHOC2(Accession Q9UQ13), corresponding to amino acid residues S532-V582.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: UQCRFS1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Uqcrfs1
Gene Alias: 4430402G14Rik; 8 kDa subunit 9; AI875505; Complex III subunit 5; Complex III subunit IX; Cytochrome b-c1 complex subunit 11; Cytochrome b-c1 complex subunit 5; Cytochrome b-c1 complex subunit 9; Cytochrome b-c1 complex subunit Rieske, mitochondrial; liver regeneration-related protein LRRGT00195; LRRGT00195; Rieske iron-sulfur protein; Rieske protein UQCRFS1; RIP1; RIS1; RISP; Su9; Ubiquinol-cytochrome c reductase 8 kDa protein; Ubiquinol-cytochrome c reductase iron-sulfur subunit; ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1; UQCR5; UQCRFS1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 291103, 66694, 7386
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P20788, P47985, Q9CR68
Gene Symbols: Uqcrfs1
Immunogen: A synthesized peptide derived from human UQCRFS1(Accession P47985), corresponding to amino acid residues V205-P255.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
UQCRFS1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Uqcrfs1
Gene Alias:
4430402G14Rik; 8 kDa subunit 9; AI875505; Complex III subunit 5; Complex III subunit IX; Cytochrome b-c1 complex subunit 11; Cytochrome b-c1 complex subunit 5; Cytochrome b-c1 complex subunit 9; Cytochrome b-c1 complex subunit Rieske, mitochondrial; liver regeneration-related protein LRRGT00195; LRRGT00195; Rieske iron-sulfur protein; Rieske protein UQCRFS1; RIP1; RIS1; RISP; Su9; Ubiquinol-cytochrome c reductase 8 kDa protein; Ubiquinol-cytochrome c reductase iron-sulfur subunit; ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1; UQCR5; UQCRFS1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
291103, 66694, 7386
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P20788, P47985, Q9CR68
Gene Symbols:
Uqcrfs1
Immunogen:
A synthesized peptide derived from human UQCRFS1(Accession P47985), corresponding to amino acid residues V205-P255.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Centrin 2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CETN2
Gene Alias: 1110034A02Rik; AI326150; CALT; Caltractin; caltractin (20kD calcium-binding protein); Caltractin isoform 1; caltractin, 20 kDa calcium binding protein; CEN2; centrin 2; centrin, EF-hand protein, 2; Centrin2; centrin-2; Cetn2; EF hand protein
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1069, 26370, 84593
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P41208, Q9R1K9
Gene Symbols: CETN2
Immunogen: A synthesized peptide derived from human CETN2(Accession P41208), corresponding to amino acid residues T45-Q95.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Centrin 2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CETN2
Gene Alias:
1110034A02Rik; AI326150; CALT; Caltractin; caltractin (20kD calcium-binding protein); Caltractin isoform 1; caltractin, 20 kDa calcium binding protein; CEN2; centrin 2; centrin, EF-hand protein, 2; Centrin2; centrin-2; Cetn2; EF hand protein
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1069, 26370, 84593
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P41208, Q9R1K9
Gene Symbols:
CETN2
Immunogen:
A synthesized peptide derived from human CETN2(Accession P41208), corresponding to amino acid residues T45-Q95.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: CEP164
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CEP164
Gene Alias: AI450905; BC027092; ce164; centrosomal protein 164; centrosomal protein 164kDa; centrosomal protein of 164 kDa; Cep 164; CEP164; D030051D21; KIAA1052; mKIAA1052; NPHP15; RGD1560988; RGD1561243
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22897, 363055, 489389
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q9UPV0
Gene Symbols: CEP164
Immunogen: A synthesized peptide derived from human CEP164(Accession Q9UPV0), corresponding to amino acid residues Q1333-G1383.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Canine, Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
CEP164
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CEP164
Gene Alias:
AI450905; BC027092; ce164; centrosomal protein 164; centrosomal protein 164kDa; centrosomal protein of 164 kDa; Cep 164; CEP164; D030051D21; KIAA1052; mKIAA1052; NPHP15; RGD1560988; RGD1561243
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22897, 363055, 489389
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q9UPV0
Gene Symbols:
CEP164
Immunogen:
A synthesized peptide derived from human CEP164(Accession Q9UPV0), corresponding to amino acid residues Q1333-G1383.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Canine, Human, Rat
Product Type:
Antibody
Isotype:
IgG