PIPA5107120
EXOSC6 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5107120-Each-of-1 | In Stock | ₹ 47,614.14 |
PIPA5107120 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,614.14
GST (18%): ₹ 8,570.545
Total Price: ₹ 56,184.685
Antigen
EXOSC6
Classification
Polyclonal
Conjugate
Unconjugated
Gene
EXOSC6
Gene Alias
2610510N21Rik; C76919; EAP4; Exosc6; Exosome complex component MTR3; exosome complex exonuclease MTR3; exosome component 6; hMtr3; hMtr3p; homolog of yeast mRNA transport regulator 3; mRNA transport regulator 3; mRNA transport regulator 3 homolog; MTR3; Mtr3 (mRNA transport regulator 3)-homolog; Mtr3p; p11
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
118460
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Western Blot
Concentration
0.5 mg/mL
Formulation
PBS with 2% sucrose and 0.09% sodium azide; pH 7.4
Gene Accession No.
Q5RKV6
Gene Symbols
EXOSC6
Immunogen
Synthetic peptide located within the following region: LYAADEEEAP GTRDPTRLRP VYARAGLLSQ AKGSAYLEAG GTKVLCAVSG
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Description Sequence homology: Cow: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%; Zebrafish: 86% Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events
- In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm
- The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates
- In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs
- It seems to be involved in degradation of histone mRNA
- The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes.
Compare Similar Items
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Antigen: EXOSC6
Classification: Polyclonal
Conjugate: Unconjugated
Gene: EXOSC6
Gene Alias: 2610510N21Rik; C76919; EAP4; Exosc6; Exosome complex component MTR3; exosome complex exonuclease MTR3; exosome component 6; hMtr3; hMtr3p; homolog of yeast mRNA transport regulator 3; mRNA transport regulator 3; mRNA transport regulator 3 homolog; MTR3; Mtr3 (mRNA transport regulator 3)-homolog; Mtr3p; p11
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 118460
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 2% sucrose and 0.09% sodium azide; pH 7.4
Gene Accession No.: Q5RKV6
Gene Symbols: EXOSC6
Immunogen: Synthetic peptide located within the following region: LYAADEEEAP GTRDPTRLRP VYARAGLLSQ AKGSAYLEAG GTKVLCAVSG
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
EXOSC6
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
EXOSC6
Gene Alias:
2610510N21Rik; C76919; EAP4; Exosc6; Exosome complex component MTR3; exosome complex exonuclease MTR3; exosome component 6; hMtr3; hMtr3p; homolog of yeast mRNA transport regulator 3; mRNA transport regulator 3; mRNA transport regulator 3 homolog; MTR3; Mtr3 (mRNA transport regulator 3)-homolog; Mtr3p; p11
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
118460
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 2% sucrose and 0.09% sodium azide; pH 7.4
Gene Accession No.:
Q5RKV6
Gene Symbols:
EXOSC6
Immunogen:
Synthetic peptide located within the following region: LYAADEEEAP GTRDPTRLRP VYARAGLLSQ AKGSAYLEAG GTKVLCAVSG
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: FAM49A
Classification: Polyclonal
Conjugate: Unconjugated
Gene: FAM49A
Gene Alias: 2410157M17Rik; 9630047E15; D12Ertd553e; FAM49A; family with sequence similarity 49 member A; family with sequence similarity 49, member A; family with sequence similarity 49, member B; protein FAM49A
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 81553
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 2% sucrose and 0.09% sodium azide; pH 7.4
Gene Accession No.: Q9H0Q0
Gene Symbols: FAM49A
Immunogen: Synthetic peptide located within the following region: GAFCKTSKID MKGCIKVLKE QAPDSVEGLL NALRFTTKHL NDESTSKQIR
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
FAM49A
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
FAM49A
Gene Alias:
2410157M17Rik; 9630047E15; D12Ertd553e; FAM49A; family with sequence similarity 49 member A; family with sequence similarity 49, member A; family with sequence similarity 49, member B; protein FAM49A
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
81553
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 2% sucrose and 0.09% sodium azide; pH 7.4
Gene Accession No.:
Q9H0Q0
Gene Symbols:
FAM49A
Immunogen:
Synthetic peptide located within the following region: GAFCKTSKID MKGCIKVLKE QAPDSVEGLL NALRFTTKHL NDESTSKQIR
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: FANCE
Classification: Polyclonal
Conjugate: Unconjugated
Gene: FANCE
Gene Alias: 2810451D06Rik; AI415634; AW209126; FACE; FAE; FANCE; Fanconi anemia complementation group E; Fanconi anemia group E protein; Fanconi anemia, complementation group E; Protein FACE; RGD1561045
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2178
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 2% sucrose and 0.09% sodium azide; pH 7.4
Gene Accession No.: Q9HB96
Gene Symbols: FANCE
Immunogen: Synthetic peptide located within the following region: SPQAPDPEEE ENRDSQQPGK RRKDSEEEAA SPEGKRVPKR LRCWEEEEDH
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
FANCE
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
FANCE
Gene Alias:
2810451D06Rik; AI415634; AW209126; FACE; FAE; FANCE; Fanconi anemia complementation group E; Fanconi anemia group E protein; Fanconi anemia, complementation group E; Protein FACE; RGD1561045
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2178
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 2% sucrose and 0.09% sodium azide; pH 7.4
Gene Accession No.:
Q9HB96
Gene Symbols:
FANCE
Immunogen:
Synthetic peptide located within the following region: SPQAPDPEEE ENRDSQQPGK RRKDSEEEAA SPEGKRVPKR LRCWEEEEDH
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: FBP2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: FBP2
Gene Alias: D-fructose-1,6-bisphosphate 1-phosphohydrolase 2; Fbp1; Fbp-1; FBP2; FBPase; FBPase 2; FBPase muscle; fructose bisphosphatase 2; fructose-1; fructose-1,6-bisphosphatase 2; fructose-1,6-bisphosphatase isozyme 2; fructose-bisphosphatase 2; hexosediphosphatase; muscle FBPase; muscle fructose-bisphosphatase; Rae-30
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 8789
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 2% sucrose and 0.09% sodium azide; pH 7.4
Gene Accession No.: O00757
Gene Symbols: FBP2
Immunogen: Synthetic peptide located within the following region: YAKYFDAATT EYVQKKKFPE DGSAPYGARY VGSMVADVHR TLVYGGIFLY
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
FBP2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
FBP2
Gene Alias:
D-fructose-1,6-bisphosphate 1-phosphohydrolase 2; Fbp1; Fbp-1; FBP2; FBPase; FBPase 2; FBPase muscle; fructose bisphosphatase 2; fructose-1; fructose-1,6-bisphosphatase 2; fructose-1,6-bisphosphatase isozyme 2; fructose-bisphosphatase 2; hexosediphosphatase; muscle FBPase; muscle fructose-bisphosphatase; Rae-30
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
8789
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 2% sucrose and 0.09% sodium azide; pH 7.4
Gene Accession No.:
O00757
Gene Symbols:
FBP2
Immunogen:
Synthetic peptide located within the following region: YAKYFDAATT EYVQKKKFPE DGSAPYGARY VGSMVADVHR TLVYGGIFLY
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG