PIPA5109310
Nephrin Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5109310-Each-of-1 | In Stock | ₹ 44,277.30 |
PIPA5109310 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,277.30
GST (18%): ₹ 7,969.914
Total Price: ₹ 52,247.214
Antigen
Nephrin
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Nphs1
Gene Alias
CNF; Nephrin; nephrin 1; NephrinB; nephrosis 1 homolog, nephrin; nephrosis 1, congenital, Finnish type (nephrin); nephrosis 1, nephrin; NPHN; NPHS1; NPHS1 nephrin; NPHS1, nephrin; renal glomerulus-specific cell adhesion receptor
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
4868
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles, store in dark
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
O60500
Gene Symbols
Nphs1
Immunogen
Recombinant protein within Human Nephrin aa 1,042-1,241
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Control: Human kidney tissue, 293T, PANC-1, PC-12
- Primary steroid resistant nephrotic syndrome (SRNS) is characterized by childhood onset of proteinuria and progression to end stage renal disease
- Kidney podocytes and their slit diaphragms form the final barrier to urinary protein loss
- Congenital nephrotic syndrome (CNS) is caused by mutations in NPHS1 (nephrin) or NPHS2
- Nephrin, a recently identified protein is a member of a group of podocyte proteins that constitute major component of the slit diaphragm especially in the foot process
- Nephrin, a cell adhesion molecule, may play a crucial role in maintaining the glomerular filtration barrier
- Recent studies have suggested that mutations in the gene for Nephrin reportedly lead to congenital nephrosis
- Three novel podocyte proteins, Podocin, Nephrin and alpha Actinin 4 have been identified in congenital and experimental models of proteinuria
- The role of Nephrin in anti apoptotic activity in podocyte slit diaphragm is believed to be associated with vascular endothelial derived growth factors VEGF signaling
- Nephrin seems to play a role in the development or function of the kidney glomerular filtration barrier and it may anchor the podocyte slit diaphragm to the actin cytoskeleton.
Compare Similar Items
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Antigen: Nephrin
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Nphs1
Gene Alias: CNF; Nephrin; nephrin 1; NephrinB; nephrosis 1 homolog, nephrin; nephrosis 1, congenital, Finnish type (nephrin); nephrosis 1, nephrin; NPHN; NPHS1; NPHS1 nephrin; NPHS1, nephrin; renal glomerulus-specific cell adhesion receptor
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4868
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles, store in dark
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: O60500
Gene Symbols: Nphs1
Immunogen: Recombinant protein within Human Nephrin aa 1,042-1,241
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Nephrin
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Nphs1
Gene Alias:
CNF; Nephrin; nephrin 1; NephrinB; nephrosis 1 homolog, nephrin; nephrosis 1, congenital, Finnish type (nephrin); nephrosis 1, nephrin; NPHN; NPHS1; NPHS1 nephrin; NPHS1, nephrin; renal glomerulus-specific cell adhesion receptor
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4868
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles, store in dark
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
O60500
Gene Symbols:
Nphs1
Immunogen:
Recombinant protein within Human Nephrin aa 1,042-1,241
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: SEL1L
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SEL1L
Gene Alias: AW493766; fj60e07; IBD2; mKIAA4137; PRO1063; Protein sel-1 homolog 1; Sel1 (suppressor of lin-12) 1 homolog; sel-1 suppressor of lin-12-like; sel-1 suppressor of lin-12-like (C. elegans); sel-1 suppressor of lin-12-like 1; Sel1h; SEL1L; sel-1L; SEL1L adaptor subunit of ERAD E3 ubiquitin ligase; SEL1L ERAD E3 ligase adaptor subunit; SEL1L, ERAD E3 ligase adaptor subunit; SEL1L1; SEL1-LIKE; si:dkey-177p2.3; Suppressor of lin 12 (sel-1), C. elegans, homolog of; suppressor of lin-12-like protein 1; TSA305; UNQ128/PRO1063; wu:fj60e07; zgc:56075
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 568615
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles, store in dark
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: 0
Gene Symbols: SEL1L
Immunogen: Recombinant protein within zebrafish SEL1L aa 109-281
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Zebrafish
Product Type: Antibody
Isotype: IgG
Antigen:
SEL1L
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SEL1L
Gene Alias:
AW493766; fj60e07; IBD2; mKIAA4137; PRO1063; Protein sel-1 homolog 1; Sel1 (suppressor of lin-12) 1 homolog; sel-1 suppressor of lin-12-like; sel-1 suppressor of lin-12-like (C. elegans); sel-1 suppressor of lin-12-like 1; Sel1h; SEL1L; sel-1L; SEL1L adaptor subunit of ERAD E3 ubiquitin ligase; SEL1L ERAD E3 ligase adaptor subunit; SEL1L, ERAD E3 ligase adaptor subunit; SEL1L1; SEL1-LIKE; si:dkey-177p2.3; Suppressor of lin 12 (sel-1), C. elegans, homolog of; suppressor of lin-12-like protein 1; TSA305; UNQ128/PRO1063; wu:fj60e07; zgc:56075
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
568615
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles, store in dark
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
0
Gene Symbols:
SEL1L
Immunogen:
Recombinant protein within zebrafish SEL1L aa 109-281
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Zebrafish
Product Type:
Antibody
Isotype:
IgG
Antigen: CD13
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ANPEP
Gene Alias: alanyl (membrane) aminopeptidase; alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD13, p150); alanyl aminopeptidase; alanyl aminopeptidase, membrane; aminopeptidase; aminopeptidase Ey; Aminopeptidase M; aminopeptidase N; aminopeptidase N.; aminopeptidase N/CD13; Anpep; APDE; Apm; AP-M; APN; AP-N; bAPN; cAPN; Cd13; cluster of differentiation antigen 13 (CD13); fAPN; gp130; gp150; h AP-N; hAPN; kidney aminopeptidase M; kidney Zn peptidase; KZP; Lap1; Lap-1; leucine arylaminopeptidase 1; LOW QUALITY PROTEIN: aminopeptidase N; membrane alanine aminiopeptidase; membrane alanine aminopeptidase; membrane alanyl aminopeptidase; membrane protein p161; Microsomal aminopeptidase; myeloid plasma membrane glycoprotein CD13; p150; pAPN; PEPN; porcine aminopeptidase N; rAPN; rbAPN; Unknown (protein for MGC:126949)
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16790, 290
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles, store in dark
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: P15144, P97449
Gene Symbols: ANPEP
Immunogen: Recombinant protein within Human CD13 aa 273-448
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
CD13
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ANPEP
Gene Alias:
alanyl (membrane) aminopeptidase; alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD13, p150); alanyl aminopeptidase; alanyl aminopeptidase, membrane; aminopeptidase; aminopeptidase Ey; Aminopeptidase M; aminopeptidase N; aminopeptidase N.; aminopeptidase N/CD13; Anpep; APDE; Apm; AP-M; APN; AP-N; bAPN; cAPN; Cd13; cluster of differentiation antigen 13 (CD13); fAPN; gp130; gp150; h AP-N; hAPN; kidney aminopeptidase M; kidney Zn peptidase; KZP; Lap1; Lap-1; leucine arylaminopeptidase 1; LOW QUALITY PROTEIN: aminopeptidase N; membrane alanine aminiopeptidase; membrane alanine aminopeptidase; membrane alanyl aminopeptidase; membrane protein p161; Microsomal aminopeptidase; myeloid plasma membrane glycoprotein CD13; p150; pAPN; PEPN; porcine aminopeptidase N; rAPN; rbAPN; Unknown (protein for MGC:126949)
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16790, 290
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles, store in dark
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P15144, P97449
Gene Symbols:
ANPEP
Immunogen:
Recombinant protein within Human CD13 aa 273-448
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: Cytokeratin 7
Classification: Polyclonal
Conjugate: Unconjugated
Gene: KRT7
Gene Alias: CK7; CK-7; Cytokeratin 7; cytokeratin-7; D15Wsu77e; K2C7; K7; Kb7; keratin 7; keratin 7, type II; keratin associated protein 7.1; keratin complex 2, basic, gene 7; keratin, 55K type II cytoskeletal; keratin, simple epithelial type I, K7; keratin, type II cytoskeletal 7; Keratin-7; keratin-associated protein 7-1; keratin-associated protein 7-1-like protein; Krt2-7; KRT7; krt7 {ECO:0000250; LOC100755511; LOC100861181; NACHT, LRR and PYD domains-containing protein 3; sarcolectin; SCL; si:ch73-233m11.1; si:ch73-233m11.2; similar to keratin 7; type II keratin Kb7; type II mesothelial keratin K7; type-II keratin Kb7; UniProtKB:P08729}
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3855
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles, store in dark
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: P08729
Gene Symbols: KRT7
Immunogen: Recombinant protein within Human Cytokeratin 7 aa 292-431
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Cytokeratin 7
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
KRT7
Gene Alias:
CK7; CK-7; Cytokeratin 7; cytokeratin-7; D15Wsu77e; K2C7; K7; Kb7; keratin 7; keratin 7, type II; keratin associated protein 7.1; keratin complex 2, basic, gene 7; keratin, 55K type II cytoskeletal; keratin, simple epithelial type I, K7; keratin, type II cytoskeletal 7; Keratin-7; keratin-associated protein 7-1; keratin-associated protein 7-1-like protein; Krt2-7; KRT7; krt7 {ECO:0000250; LOC100755511; LOC100861181; NACHT, LRR and PYD domains-containing protein 3; sarcolectin; SCL; si:ch73-233m11.1; si:ch73-233m11.2; similar to keratin 7; type II keratin Kb7; type II mesothelial keratin K7; type-II keratin Kb7; UniProtKB:P08729}
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3855
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles, store in dark
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P08729
Gene Symbols:
KRT7
Immunogen:
Recombinant protein within Human Cytokeratin 7 aa 292-431
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG