PIPA5109592

CRX Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5109592-Each-of-1 In Stock ₹ 44,705.10

PIPA5109592 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

CRX

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Crx

Gene Alias

Cone rod homeobox; cone-rod homeobox; cone-rod homeobox containing; cone-rod homeobox protein; CORD 2; CORD2; CRD; CRX; Crx1; LCA 7; LCA7; orthodenticle homeobox 3; OTX; OTX 3; OTX3

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12951

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1.08 mg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3

Gene Accession No.

O54751

Gene Symbols

Crx

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 100-200 of human CRX (NP_0005451)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: QQKQQQQPPG GQAKARPAKR KAGTSPRPST DVCPDPLGIS DSYSPPLPGP SGSPTTAVAT VSIWSPASES PLPEAQRAGL VASGPSLTSA PYAMTYAPAS A The cone-rod homeobox-containing gene (CRX) encodes a transcription factor that coordinates the expression of several photoreceptor genes in the developing retina, including opsin and rhodopsin
  • Specifically, CRX binds the OTX motif (TAATCC/A) upstream from photoreceptor genes
  • The CRX gene is also expressed in the pinealocytes of the pineal gland and may regulate pineal circadian activity by controling the expression of melatonin synthesis genes
  • Furthermore, CRX(-) mice exhibit disruption of circadian rhythms
  • The human CRX gene maps to chromosome 19q13.3 within the region of the cone-rod dystrophy-2 locus (CORD2)
  • Mutations in the CRX gene are implicated in the visual pathologies of CORD, Leber congenital amaurosis (LCA) and retinitis pigmentosa (RP)
  • All characterized CRX gene mutations produce disease in heterozygotes although there is no known correlation between the pathologic phenotype and genetic mutation
  • Missense mutations of the CRX gene affect the homeobox domain, whereas frameshift mutations affect the OTX domain.

Compare Similar Items

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Img

Thermo Scientific

PIPA5109592

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Antigen:
CRX

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Crx

Gene Alias:
Cone rod homeobox; cone-rod homeobox; cone-rod homeobox containing; cone-rod homeobox protein; CORD 2; CORD2; CRD; CRX; Crx1; LCA 7; LCA7; orthodenticle homeobox 3; OTX; OTX 3; OTX3

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12951

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1.08 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3

Gene Accession No.:
O54751

Gene Symbols:
Crx

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human CRX (NP_0005451)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5109593

--


Antigen:
CRY2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CRY2

Gene Alias:
AV006279; CRY2; cryptochrome 2 (photolyase-like); cryptochrome circadian clock 2; cryptochrome-2; D130054K12Rik; growth-inhibiting protein 37; HCRY2; Kiaa0658; PHLL2

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1408, 170917

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.56 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
Q49AN0, Q923I8

Gene Symbols:
CRY2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 200-300 of human CRY2 (NP_0669403)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5109594

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Antigen:
CRYBB2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Crybb2

Gene Alias:
Beta crystallin B2; Beta crystallin Bp; beta-B2 crystallin; Beta-crystallin B2; beta-crystallin Bp; CCA 2; CCA2; CRYB B2; CRYB2; Cryb-2; CRYB2A; CRYBB 2; CRYBB2; crystallin beta B2; crystallin, beta B2; CTA-221G9.7; CTRCT3; D22S665; eye lens structural protein; OTTHUMP00000198622; R.norvegicus CRYBB2 gene (crystallin, beta B2)

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12961, 1415, 25422

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.59 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P43320, P62696, P62697

Gene Symbols:
Crybb2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-205 of human CRYBB2 (NP_000487.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5109595

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Antigen:
CRYGB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CRYGB

Gene Alias:
Cryg2; Cryg-3; CRY-gamma-B; Crygb; crystallin gamma B; crystallin, gamma 1-2; crystallin, gamma B; crystallin, gamma polypeptide 2; CTRCT39; DGcry-3; Gamma-B-crystallin; gammaB-crystallin; gamma-crystallin 1-2; Gamma-crystallin 3; gamma-crystallin B; Len; Nop; nuclear opacity

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12965, 301468

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.06 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
P04344, P10066

Gene Symbols:
CRYGB

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 80-135 of human CRYGB (NP_005201.2).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG