PIPA5109631

DGUOK Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5109631-Each-of-1 In Stock ₹ 44,705.10

PIPA5109631 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

DGUOK

Classification

Polyclonal

Conjugate

Unconjugated

Gene

DGUOK

Gene Alias

deoxyguanosine kinase; deoxyguanosine kinase, mitochondrial; dGK; dGK1; dGK2; dGK3; DGUOK; MTDPS3

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1716, 27369, 297389

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.85 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q16854, Q9QX60

Gene Symbols

DGUOK

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 40-277 of human DGUOK (NP_550438.1).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: RLSIEGNIAV GKSTFVKLLT KTYPEWHVAT EPVATWQNIQ AAGTQKACTA QSLGNLLDMM YREPARWSYT FQTFSFLSRL KVQLEPFPEK LLQARKPVQI FERSVYSDRY IFAKNLFENG SLSDIEWHIY QDWHSFLLWE FASRITLHGF IYLQASPQVC LKRLYQRARE EEKGIELAYL EQLHGQHEAW LIHKTTKLHF EALMNIPVLV LDVNDDFSEE VTKQEDLMRE VNTFVKNL Mitochondrial deoxyguanosine kinase (DGUOK) is required for the phosphorylation of several deoxyribonucleosides and certain purine deoxykribonucleoside analogs widely employed as antiviral and chemotherapeutic agents
  • Purine deoxyribonucleoside analogs are extensively used in treatment of lymphoproliferative disorders
  • These compounds are administered as pro-drugs, and their efficiency is dependent on intracellular phosphorylation to the corresponding triphosphates
  • In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by 2 deoxyribonucleoside kinases: cytosolic deoxycytidine kinase (DCK) and mitochondrial deoxyguanosine kinase (DGUOK also known as DGK)
  • DGUOK expression is ubiquitous, with highest levels in muscle, brain, liver and lymphoid tissues
  • Defects in DGUOK are a cause of mitochondrial DNA depletion syndrome (MDS)
  • MDS is a clinically heterogeneous group of disorders characterized by a reduction in mitochondrial DNA (mtDNA) copy number
  • Primary mtDNA depletion is inherited as an autosomal recessive trait and may affect single organs, typically muscle or liver, or multiple tissues.

Compare Similar Items

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Thermo Scientific

PIPA5109631

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Antigen:
DGUOK

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DGUOK

Gene Alias:
deoxyguanosine kinase; deoxyguanosine kinase, mitochondrial; dGK; dGK1; dGK2; dGK3; DGUOK; MTDPS3

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1716, 27369, 297389

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.85 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q16854, Q9QX60

Gene Symbols:
DGUOK

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 40-277 of human DGUOK (NP_550438.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5109632

--


Antigen:
DHDH

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DHDH

Gene Alias:
1300018L09Rik; 2DD; 3-deoxyglucosone reductase; AA591799; CAN2DD; ch211-203b17.3; DDH; DHDH; dhdh.2; dhdh-like.1.L; dihydrodiol dehydrogenase; dihydrodiol dehydrogenase (dimeric); dihydrodiol dehydrogenase, tandem duplicate 2; dimeric dihydrodiol dehydrogenase; D-xylose 1-dehydrogenase; D-xylose-NADP dehydrogenase; Hum2DD; putative LOC617564 protein; SUS2DD; Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase L homeolog; XELAEV_18036112mg; Xld1; Xld-1; xylose dehydrogenase 1; zgc:101723

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
71755

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.94 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9DBB8

Gene Symbols:
DHDH

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-334 of human DHDH (NP_055290.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5109633

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Antigen:
DHH

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Dhh

Gene Alias:
C78960; desert hedgehog; desert hedgehog protein; Desert hedgehog protein C-product; Desert hedgehog protein N-product; Dhh; GDXYM; HHG-3; SRXY7

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13363, 50846, 84380

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
3.7 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
O43323, Q61488

Gene Symbols:
Dhh

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 199-396 of human DHH (NP_066382.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5109635

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Antigen:
LGP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DHX58

Gene Alias:
B430001I08Rik; D11LGP2; D11lgp2e; DEXH (Asp-Glu-X-His) box polypeptide 58; DEXH-box helicase 58; DHX58; Lgp2; LPG2; ortholog of mouse D11lgp2; probable ATP-dependent helicase LGP2; Probable ATP-dependent RNA helicase DHX58; protein D11Lgp2; Protein D11Lgp2 homolog; RGD1310093; RIG-I-like receptor 3; RIG-I-like receptor Lgp2; RLR; RLR-3; RNA helicase LGP2

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
303538, 79132, 80861

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
2.08 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q96C10, Q99J87

Gene Symbols:
DHX58

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 389-678 of human DHX58 (NP_077024.2).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG