PIPA5109637

DLAT Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5109637-Each-of-1 In Stock ₹ 44,705.10

PIPA5109637 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

DLAT

Classification

Polyclonal

Conjugate

Unconjugated

Gene

DLAT

Gene Alias

6332404G05Rik; 70 kDa mitochondrial autoantigen of primary biliary cirrhosis; anti DLAT; Dihydrolipoamide; Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; dihydrolipoamide S-acetyltransferase; dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex); dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex mitochondrial; dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial; DLAT; DLTA; E2; E2 component of pyruvate dehydrogenase complex; EC 2.3.1.12; M2 antigen complex 70 kDa subunit; ODP2; PBC; PDC PDC-E2; PDCE2; PDC-E2; pyruvate dehydrogenase complex component E2

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1737, 235339, 81654

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

0.16 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

P08461, P10515, Q8BMF4

Gene Symbols

DLAT

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human DLAT (NP_001922.2).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: MWRVCARRAQ NVAPWAGLEA RWTALQEVPG TPRVTSRSGP APARRNSVTT GYGGVRALCG WTPSSGATPR NRLLLQLLGS PGRRYYSLPP HQKVPLPSLS PTMQAGTIAR WEKKEGDKIN EGDLIAEVET DKATVGFESL EECYMAKILV AEGTRDVPIG AIICITVGKP EDIEAFKNYT LDSSAAPTPQ AAPAPTPAAT ASPPTPSAQA PGSSYPPHMQ VLLPALSPTM TMGTVQRWEK KVGEKLSEGD LLAEIETDKA TIGFEVQEEG YLAKILVPEG TRDVPLGTPL DLAT encodes component E2 of the multi-enzyme pyruvate dehydrogenase complex (PDC)
  • PDC resides in the inner mitochondrial membrane and catalyzes the conversion of pyruvate to acetyl coenzyme A
  • The protein product of this gene, dihydrolipoamide acetyltransferase, accepts acetyl groups formed by the oxidative decarboxylation of pyruvate and transfers them to coenzyme A
  • Dihydrolipoamide acetyltransferase is the antigen for antimitochondrial antibodies
  • These autoantibodies are present in nearly 95% of patients with the autoimmune liver disease primary biliary cirrhosis (PBC)
  • In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed
  • PBC eventually leads to cirrhosis and liver failure.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA5109637

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Antigen:
DLAT

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DLAT

Gene Alias:
6332404G05Rik; 70 kDa mitochondrial autoantigen of primary biliary cirrhosis; anti DLAT; Dihydrolipoamide; Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; dihydrolipoamide S-acetyltransferase; dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex); dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex mitochondrial; dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial; DLAT; DLTA; E2; E2 component of pyruvate dehydrogenase complex; EC 2.3.1.12; M2 antigen complex 70 kDa subunit; ODP2; PBC; PDC PDC-E2; PDCE2; PDC-E2; pyruvate dehydrogenase complex component E2

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1737, 235339, 81654

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.16 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P08461, P10515, Q8BMF4

Gene Symbols:
DLAT

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human DLAT (NP_001922.2).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5109638

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Antigen:
DLST

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Dlst

Gene Alias:
1600017E01Rik; 2-oxoglutarate dehydrogenase complex component E2; 4632413C10Rik; 4930529O08Rik; dihydrolipoamide S-succinyltransferase; dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex); dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; Dihydrolipoyllysine-residue succinyltransferase; dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial; DLST; DLTS; E2; E2K; OGDC-E2

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1743, 299201, 78920

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.55 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P36957, Q01205, Q9D2G2

Gene Symbols:
Dlst

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 150-250 of human DLST (NP_001924.2).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5109639

--


Antigen:
DLST

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Dlst

Gene Alias:
1600017E01Rik; 2-oxoglutarate dehydrogenase complex component E2; 4632413C10Rik; 4930529O08Rik; dihydrolipoamide S-succinyltransferase; dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex); dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; Dihydrolipoyllysine-residue succinyltransferase; dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial; DLST; DLTS; E2; E2K; OGDC-E2

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1743, 299201, 78920

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.55 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P36957, Q01205, Q9D2G2

Gene Symbols:
Dlst

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human DLST (NP_001924.2).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5109640

--


Antigen:
DLX3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Dlx3

Gene Alias:
AI4; AV237891; DII C; distal-less homeobox 3; Dlx3; Dlx-3; Homeobox protein DLX-3; LOW QUALITY PROTEIN: homeobox protein DLX-3; TDO

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13393, 287638

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
3.92 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q64205

Gene Symbols:
Dlx3

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human DLX3 (NP_005211.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG