PIPA5109788

GRK1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5109788-Each-of-1 In Stock ₹ 44,191.74

PIPA5109788 - Each of 1

₹ 44,191.74

In Stock

Quantity

1

Base Price: ₹ 44,191.74

GST (18%): ₹ 7,954.513

Total Price: ₹ 52,146.253

Antigen

GRK1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GRK1

Gene Alias

G protein-coupled receptor kinase 1; G protein-coupled receptpr kinase 1; GPRK1; G-protein coupled receptor kinase 1; G-protein receptor kinase 1; GRK 1a/b; GRK1; GRK1a; rhodopsin kinase; rhodopsin kinase GRK1; Rhok; RK

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

24013, 6011, 81760

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1.19 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q15835, Q63651, Q9WVL4

Gene Symbols

GRK1

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human GRK1 (NP_002920.1).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: MDFGSLETVV ANSAFIAARG SFDGSSSQPS RDKKYLAKLK LPPLSKCESL RDSLSLEFES VCLEQPIGKK LFQQFLQSAE KHLPALELWK DIEDYDTADN DLQPQKAQTI LAQYLDPQAK LFCSFLDEGI VAKFKEGPVE IQDGLFQPLL QATLAHLGQA GRK1 is a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinases
  • GRK1 mediates rapid desensitization of rod photoreceptors to light by catalyzing phosphorylation of the visual pigment rhodopsin which leads to its deactivation
  • Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2)
  • GRK1 can be phosphorylated by PKA and this reduces the ability of GRK1 to phosphorylate rhodopsin in vitro
  • It is speculated that phosphorylation of GRK1 by PKA in vivo occurs in the dark when cAMP levels in photoreceptor cells are elevated.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5109788

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Antigen:
GRK1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GRK1

Gene Alias:
G protein-coupled receptor kinase 1; G protein-coupled receptpr kinase 1; GPRK1; G-protein coupled receptor kinase 1; G-protein receptor kinase 1; GRK 1a/b; GRK1; GRK1a; rhodopsin kinase; rhodopsin kinase GRK1; Rhok; RK

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
24013, 6011, 81760

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.19 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q15835, Q63651, Q9WVL4

Gene Symbols:
GRK1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human GRK1 (NP_002920.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5109789

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Antigen:
GRPEL1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GRPEL1

Gene Alias:
AA408748; FLJ25609; GREPEL1; GrpE; GrpE like 1, mitochondrial; grpE protein homolog 1, mitochondrial; GrpE#1; GrpE1; GRPEL1; GrpE-like 1; GrpE-like 1, mitochondrial; GrpE-like protein cochaperone; HMGE; mt-GrpE#1; mt-Grpel1; stress-inducible chaperone mt-GrpE#1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17713, 79563, 80273

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1.37 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P97576, Q99LP6, Q9HAV7

Gene Symbols:
GRPEL1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-217 of human GRPEL1 (NP_079472.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5109791

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Antigen:
GSDMB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GSDMB

Gene Alias:
gasdermin B; gasdermin-B; Gasdermin-like protein; GSDMB; GSDML; PP4052; PRO2521

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
55876

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
3.52 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q8TAX9

Gene Symbols:
GSDMB

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human GSDMB (NP_001159431.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5109794

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Antigen:
GSTT2B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GSTT2B

Gene Alias:
glutathione S-transferase theta 2; glutathione S-transferase theta 2B (gene/pseudogene); glutathione S-transferase theta-2; Glutathione S-transferase theta-2B; GST class-theta-2; GSTT2; GSTT2B; GSTT2P

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
653689

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.98 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
P0CG30

Gene Symbols:
GSTT2B

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 115-244 of human GSTT2B (NP_001074312.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG