PIPA5110049

NUDT16 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5110049-Each-of-1 In Stock ₹ 44,705.10

PIPA5110049 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

NUDT16

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NUDT16

Gene Alias

2310041H06Rik; 2810047L04Rik; 2900006H04Rik; AI851783; IDP phosphatase; IDPase; inosine diphosphate phosphatase; LOC100718706; m7GpppN-mRNA hydrolase; nucleoside diphosphate-linked moiety X motif 16; nudix; nudix (nucleoside diphosphate linked moiety X)-type motif 16; nudix hydrolase 16; Nudix motif 16; nudix-type motif 16; NUDT16; RGD1311387; testicular tissue protein Li 129; U8 snoRNA-binding protein H29K; U8 snoRNA-decapping enzyme

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

131870, 75686

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

1.56 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.

Q6P3D0, Q96DE0

Gene Symbols

NUDT16

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 60-130 of human NUDT16 (NP_689608.2).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: GFVDTQDRSL EDGLNRELRE ELGEAAAAFR VERTDYRSSH VGSGPRVVAH FYAKRLTLEE LLAVEAGATR A RNA-binding and decapping enzyme that catalyzes the cleavage of the cap structure of snoRNAs and mRNAs in a metal-dependent manner
  • Part of the U8 snoRNP complex that is required for the accumulation of mature 5.8S and 28S rRNA
  • Has diphosphatase activity and removes m7G and/or m227G caps from U8 snoRNA and leaves a 5'monophosphate on the RNA
  • Catalyzes also the cleavage of the cap structure on mRNAs
  • Does not hydrolyze cap analog structures like 7-methylguanosine nucleoside triphosphate (m7GpppG)
  • Also hydrolysis m7G- and m227G U3-capped RNAs but with less efficiencies
  • Has broad substrate specificity with manganese or cobalt as cofactor and can act on various RNA species
  • Binds to the U8 snoRNA; metal is not required for RNA-binding
  • May play a role in the regulation of snoRNAs and mRNAs degradation
  • Acts also as a phosphatase; hydrolyzes the non-canonical purine nucleotides inosine diphosphate (IDP) and deoxyinosine diphosphate (dITP) as well as guanosine diphosphate (GDP), deoxyguanosine diphosphate (dGDP), xanthine diphosphate (XDP), inosine triphosphate (ITP) and deoxyinosine triphosphate (ITP) to their respective monophosphate derivatives and does not distinguish between the deoxy- and ribose forms (PubMed:20385596, PubMed:26121039)
  • The order of activity with different substrates is IDP > dIDP >> GDP = dGDP > XDP = ITP = dITP (PubMed:20385596)
  • Binds strongly to GTP, ITP and XTP
  • Participates in the hydrolysis of dIDP/IDP and probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions (PubMed:20385596)
  • [UniProt]

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA5110049

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Antigen:
NUDT16

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NUDT16

Gene Alias:
2310041H06Rik; 2810047L04Rik; 2900006H04Rik; AI851783; IDP phosphatase; IDPase; inosine diphosphate phosphatase; LOC100718706; m7GpppN-mRNA hydrolase; nucleoside diphosphate-linked moiety X motif 16; nudix; nudix (nucleoside diphosphate linked moiety X)-type motif 16; nudix hydrolase 16; Nudix motif 16; nudix-type motif 16; NUDT16; RGD1311387; testicular tissue protein Li 129; U8 snoRNA-binding protein H29K; U8 snoRNA-decapping enzyme

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
131870, 75686

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.56 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
Q6P3D0, Q96DE0

Gene Symbols:
NUDT16

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 60-130 of human NUDT16 (NP_689608.2).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA5110050

--


Antigen:
NUFIP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Nufip2

Gene Alias:
1110001M19Rik; 182-FIP; 82 kDa FMRP-interacting protein; 82-FIP; 82-kD FMRP Interacting Protein; 9530056D24Rik; AI256692; AI461731; Cell proliferation-inducing gene 1 protein; FIP-82; FMRP-interacting protein 2; Fragile X Mental Retardation Protein; im:7136583; KIAA1321; LOW QUALITY PROTEIN: nuclear fragile X mental retardation-interacting protein 2; mKIAA1321; nuclear FMR1 interacting protein 2; nuclear FMR1 interacting protein 2; nuclear fragile X mental retardation-interacting protein 2; nuclear fragile X mental retardation protein interacting protein 2; nuclear fragile X mental retardation-interacting protein 2; NUFIP2; NUFIP2, FMR1 interacting protein 2; PIG1; proliferation-inducing gene 1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57532, 681371, 68564

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
3.76 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
Q5F2E7, Q7Z417

Gene Symbols:
Nufip2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 456-695 of human NUFIP2 (NP_065823.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5110051

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Antigen:
gp210

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NUP210

Gene Alias:
9830001L10; AI836801; FLJ22389; gp190; GP210; integral membrane nucleoporin gp210; Kiaa0906; Nuclear envelope pore membrane protein POM 210; nuclear pore membrane glycoprotein 210; nuclear pore membrane protein 210; nuclear pore protein gp210; nucleoporin 210; nucleoporin 210; nuclear pore membrane glycoprotein 210; nuclear pore membrane protein 210; nucleoporin 210kDa; nucleoporin 210kDa L homeolog; nucleoporin Nup210; NUP210; nup210.L; POM210; pore membrane protein of 210 kDa; PSEC0245; XELAEV_18001839mg

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23225, 54563, 58958

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.87 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
P11654, Q8TEM1, Q9QY81

Gene Symbols:
NUP210

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 680-880 of human NUP210 (NP_079199.2).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5110052

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Antigen:
NUP43

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NUP43

Gene Alias:
2610016K01Rik; 2610529I12Rik; AA409950; bA350J20.1; nucleoporin 43; nucleoporin 43kDa; nucleoporin Nup43; Nup107-160 subcomplex subunit Nup43; Nup43; p42

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
348995, 683983

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
2.1 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
Q8NFH3

Gene Symbols:
NUP43

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 150-260 of human NUP43 (NP_942590.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG