PIPA5110088

PDE6G Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5110088-Each-of-1 In Stock ₹ 44,705.10

PIPA5110088 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

PDE6G

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PDE6G

Gene Alias

GMP-PDE gamma; p3AT; PDE6G; PDEG; phosphodiesterase 6G; phosphodiesterase 6G, cGMP-specific, rod, gamma; phosphodiesterase, cyclic GMP (rod receptor), gamma polypeptide; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma; rod cG-PDE G; RP57; unnamed protein product

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

18588, 5148, 688297

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

4.5 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.

P09174, P18545

Gene Symbols

PDE6G

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-87 of human PDE6G (NP_002593.1).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: MNLEPPKAEF RSATRVAGGP VTPRKGPPKF KQRQTRQFKS KPPKKGVQGF GDDIPGMEGL GTDITVICPW EAFNHLELHE LAQYGII The second messengers cAMP and cGMP are key regulatory molecules that are involved in a wide variety of signal transduction pathways
  • Levels of cAMP and cGMP are regulated by their rate of synthesis by nucleotide cyclases and by their rate of hydrolysis by cyclic nucleotide phosphodiesterases (PDEs)
  • PDEs form a superfamily of enzymes that catalyze the conversion of 3-prime, 5-prime-cyclic nucleotides to the corresponding nucleoside 5-prime-monophosphates
  • PDE6 is the effector enzyme in the G protein-mediated signal transduction cascade in the visual system
  • There are five different subunits consisting of rod and cone specific catalytic subunits: alpha' (Cone), alpha (Rod), and beta (Rod), the inhibitory subunit gamma, and subunit delta of unknown function (which likely interacts with many other proteins besides the PDE6 family)
  • The catalytic core of the PDE6 system is comprised of alpha'/alpha' homodimers in the cone and alpha/beta heterodimers in the rod
  • The C-terminus of both the catalytic and inhibitory subunits is modified by methylation, myristyolation and prenylation which have been shown to be critical for proper complex assembly and membrane association.

Compare Similar Items

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Img

Thermo Scientific

PIPA5110088

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Antigen:
PDE6G

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PDE6G

Gene Alias:
GMP-PDE gamma; p3AT; PDE6G; PDEG; phosphodiesterase 6G; phosphodiesterase 6G, cGMP-specific, rod, gamma; phosphodiesterase, cyclic GMP (rod receptor), gamma polypeptide; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma; rod cG-PDE G; RP57; unnamed protein product

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18588, 5148, 688297

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
4.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
P09174, P18545

Gene Symbols:
PDE6G

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-87 of human PDE6G (NP_002593.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5110090

--


Antigen:
PDHA1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PDHA1

Gene Alias:
PDHA; PDHA1; Pdha-1; PDHAD; PDHCE1A; PDHE1-A type I; PHE1A; pyruvate dehydrogenase; pyruvate dehydrogenase (lipoamide) alpha 1; pyruvate dehydrogenase alpha 1; pyruvate dehydrogenase complex, E1-alpha polypeptide 1; pyruvate dehydrogenase E1 alpha 1; pyruvate dehydrogenase E1 alpha 1 subunit; pyruvate dehydrogenase E1 component alpha subunit; pyruvate dehydrogenase E1 component alpha subunit precursor; pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial; pyruvate dehydrogenase E1 subunit; pyruvate dehydrogenase E1 subunit alpha 1; pyruvate dehydrogenase E1alpha subunit

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18597, 29554, 5160

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
0.718 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
P08559, P26284, P35486

Gene Symbols:
PDHA1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 30-390 of human PDHA1 (NP_0002751)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5110091

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Antigen:
PDHX

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Pdhx

Gene Alias:
Ac1164; AI481367; component X; Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex; dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex (E3-binding protein) (proX); DLDBP; E3-binding protein; E3BP; GSF; IDX-1; IPF1; IPF-1; IUF-1; lipoyl-containin; lipoyl-containing pyruvate dehydrogenase complex component X; OPDX; Pdhx; PDX1; PDX-1; proX; pyruvate dehydrogenase; pyruvate dehydrogenase complex component X; pyruvate dehydrogenase complex, component X; pyruvate dehydrogenase complex, E3-binding protein subunit; pyruvate dehydrogenase complex, lipoyl-containing component X; pyruvate dehydrogenase protein X component, mitochondrial; STF-1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
27402, 311254, 8050

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
2.8 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O00330, Q8BKZ9

Gene Symbols:
Pdhx

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PDHX (NP_003468.2).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5110092

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Antigen:
PDK4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Pdk4

Gene Alias:
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial; [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial; AV005916; kinase isozyme 4; lipoamide; PDHK4; Pdk4; pyruvate dehydrogenase; pyruvate dehydrogenase kinase 4; Pyruvate dehydrogenase kinase isoform 4; pyruvate dehydrogenase kinase, isoenzyme 4; pyruvate dehydrogenase kinase, isozyme 4; pyruvate dehydrogenase, lipoamide, kinase isozyme 4, mitochondrial; pyruvate dehydrogenate kinase 4

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
27273, 5166, 89813

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
2.35 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
O54937, O70571, Q16654

Gene Symbols:
Pdk4

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 102-411 of human PDK4 (NP_0026031)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG