PIPA5110195

POLE2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5110195-Each-of-1 In Stock ₹ 44,705.10

PIPA5110195 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

POLE2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

POLE2

Gene Alias

DNA pol epsilon2; DNA pol epsilonB; DNA polymerase epsilon 2, accessory subunit; DNA polymerase epsilon small subunit; DNA polymerase epsilon subunit 2; DNA polymerase epsilon subunit B; DNA polymerase epsilon, subunit 2; DNA polymerase II subunit 2; DNApol epsilon2; DNApol epsilonB; DPE2; POLE2; polymerase (DNA directed), epsilon 2 (p59 subunit); polymerase (DNA directed), epsilon 2, accessory subunit; polymerase (DNA) epsilon 2, accessory subunit

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

18974, 5427

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.75 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.

O54956, P56282

Gene Symbols

POLE2

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human POLE2 (NP_002683.2).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: MAPERLRSRA LSAFKLRGLL LRGEAIKYLT EALQSISELE LEDKLEKIIN AVEKQPLSSN MIERSVVEAA VQECSQSVDE TIEHVFNIIG AFDIPRFVYN SERKKFLPLL MTNHPAPNLF GTPRDKAEMF RERYTILHQR THRHELFTPP VIGSHPDESG SKFQLKTIET LLGSTTKIGD AIVLGMITQL KEGKFFLEDP TGTVQLDLSK AQFHSGLYTE ACFVLAEGWF EDQVFHVNAF GFPPTEPSST TRAYYGNINF FGGPSNTSVK TSAKLKQLEE ENKDAMFVFL DNA replication, recombination and repair, all of which are necessary for genome stability, require the presence of exonucleases
  • In DNA replication, these enzymes are involved in the processing of Okazaki fragments, whereas in DNA repair, they function to excise damaged DNA fragments and correct recombinational mismatches
  • Exonucleases involved in these processes include DNA polymerases, including DNA pol delta and epsilon
  • DNA pol delta consists of two subunits-p125 which interacts directly with the sliding DNA clamp protein PCNA, and p50
  • DNA pol delta can be regulated by cell cycle proteins
  • DNA pol epsilon is a multiple subunit enzyme, the catalytic subunit of which is encoded by the POL2 gene
  • The exact reactions catalyzed by DNA pol delta and epsilon on leading and lagging strands have not yet been elucidated.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA5110195

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Antigen:
POLE2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
POLE2

Gene Alias:
DNA pol epsilon2; DNA pol epsilonB; DNA polymerase epsilon 2, accessory subunit; DNA polymerase epsilon small subunit; DNA polymerase epsilon subunit 2; DNA polymerase epsilon subunit B; DNA polymerase epsilon, subunit 2; DNA polymerase II subunit 2; DNApol epsilon2; DNApol epsilonB; DPE2; POLE2; polymerase (DNA directed), epsilon 2 (p59 subunit); polymerase (DNA directed), epsilon 2, accessory subunit; polymerase (DNA) epsilon 2, accessory subunit

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18974, 5427

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.75 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
O54956, P56282

Gene Symbols:
POLE2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human POLE2 (NP_002683.2).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA5110198

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Antigen:
POLR2F

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
POLR2F

Gene Alias:
1810060D16Rik; DNA-directed RNA polymerase II subunit F; DNA-directed RNA polymerases I, II, and III 14.4 kDa polypeptide; DNA-directed RNA polymerases I, II, and III subunit RPABC2; HRBP14.4; hsRPB6; Polr2f; POLRF; polymerase (RNA) II (DNA directed) polypeptide F; polymerase (RNA) II subunit F; polymerase II; RNA Pol II; RNA Polymerase II subunit 14.4 kD; RNA polymerase II subunit F; RNA polymerases I, II, and III subunit ABC2; RPABC14.4; RPABC2; RPB14.4; RPB6; RPB6 homolog; RPC15

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5435, 83503

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.25 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
O88828, P61218

Gene Symbols:
POLR2F

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-127 of human POLR2F (NP_068809.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5110199

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Antigen:
POLR2G

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
POLR2G

Gene Alias:
2410046K11Rik; A230108L04Rik; C76415; DNA directed RNA polymerase II 19 kda polypeptide; DNA-directed RNA polymerase II 19 kDa polypeptide; DNA-directed RNA polymerase II subunit G; DNA-directed RNA polymerase II subunit RPB7; h hsRPB7; hRPB19; hs; hsRPB7; MGC138367; MGC138369; POLR2G; polymerase (RNA) II (DNA directed) polypeptide G; polymerase (RNA) II subunit G; RBP7; RNA polymerase II 19 kDa subunit; RNA polymerase II seventh subunit; RNA polymerase II subunit B7; RNA polymerase II subunit G; RPB19; RPB7; Rpo2-7l

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
117017, 5436, 67710

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.53 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P62487, P62488, P62489

Gene Symbols:
POLR2G

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-172 of human POLR2G (NP_002687.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5110205

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Antigen:
PPP1CB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ppp1cb

Gene Alias:
1200010B19; epididymis secretory sperm binding protein Li 80p; HEL-S-80p; hypothetical protein LOC538829; MGC21657; PP1B; PP-1B; PP1beta; PP1-BETA; PP2CB; PP2CBETA; PP2C-beta-X; PPC2BETAX; PPP1CB; PPP1CD; protein phosphatase 1; protein phosphatase 1 catalytic subunit beta; protein phosphatase 1, catalytic subunit, beta isoform; protein phosphatase 1, catalytic subunit, beta isozyme; protein phosphatase 1, catalytic subunit, delta isoform; protein phosphatase 1-beta; protein phosphatase 1-delta; protein phosphatase-1a; serine/threonine protein phosphatase PP1-beta catalytic subunit; serine/threonine-protein phosphatase PP1-beta catalytic subunit

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19046, 25594, 5500

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.15 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
P62140, P62141, P62142

Gene Symbols:
Ppp1cb

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 227-327 of human PP1 beta (NP_0027001)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG